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VEGF is a substance made by cells that stimulates new blood vessel formation. Also called vascular endothelial growth factor.

Study reveals inflammation's role in long COVID's lingering effects

Large-scale study found that long COVID patients exhibit sustained inflammation and specific immune responses associated with varying symptoms, highlighting the importance of personalized treatment approaches.

9 Apr 2024

miR-205 knockout surprises with enhanced mammary development and cancer insights

New research unveils the paradoxical role of miR-205 in mammary gland development and its potential impact on breast cancer, highlighting the miRNA's complex involvement in stem cell regulation and tumor suppression.

2 Apr 2024

Study reveals new strategy to improve and accelerate recovery from muscle injuries

Muscle injuries are common in the active population, and they cause the majority of player leaves in the world of sport.

19 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Study unravels FOXO1's influence on blood vessel development

The human vascular system, a complex network of blood vessels, plays an essential role in maintaining health. Understanding the molecular mechanisms underlying vascular development is important for tackling age-related disorders.

9 Mar 2024

Exonate first-in-class eye drop Phase Ib/IIa trial data demonstrate safety and biological activity in treatment of diabetic retinopathy and diabetic macular oedema

EXN407 is the first topical SRPK1 inhibitor to demonstrate both safety and signals of biological response as monotherapy for these indications.

5 Mar 2024

New treatment targeting aging cells could offer lasting relief for diabetic macular edema

Targeting senescent cells in the retina with a BCL-xL inhibitor shows promise as a durable treatment for diabetic macular edema, potentially offering long-term visual function improvements.

8 Feb 2024

Pazopanib activity confirmed in EWSR1-NFATC2 bone sarcoma

A new case report was published in Oncoscience (Volume 10) on September 20, 2023, entitled, "Activity of pazopanib in EWSR1-NFATC2 translocation-associated bone sarcoma."

12 Jan 2024

Ginseng's hidden gems: Rare ginsenosides emerge as potent players in the future of medicine

Review in the Journal of Advanced Research summarizes the properties, applications, and production of rare ginsenosides (RGs), highlighting their potential in treating various diseases including cancer and cardiovascular ailments.

8 Jan 2024

Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Exonate announces successful completion of Phase Ib/IIa trial in diabetic macular oedema

Lead ophthalmology candidate EXN407 has potential to be the first topical treatment for diabetic retinopathy/diabetic macular oedema.

28 Nov 2023

Exploring the impact of soy isoflavones in prostate cancer therapy

The cellular mechanisms of soy isoflavones, genistein, daidzein, and equol.

23 Nov 2023

Falk Trust awards $1.35 million to Case Western Reserve researchers for cancer and diabetic retinopathy treatments

A combined $1.35 million from the Dr. Ralph and Marian Falk Medical Research Trust was awarded to two researchers from the Case Western Reserve University School of Medicine to advance their work on finding more effective treatments-;and better options-;for two debilitating diseases.

17 Nov 2023

Fecal microbiota transplantation boosts survival in metastatic colorectal cancer treatment

A recent study in eClinicalMedicine found that fecal microbiota transplantation, combined with fruquintinib and tislelizumab, significantly improved survival rates in patients with microsatellite stable metastatic colorectal cancer, showing manageable safety and notable increases in progression-free and overall survival.

15 Nov 2023

Children need to be screened for vision problems as often as adults with sickle cell disease, study suggests

Sickle cell disease is a rare, inherited disorder in which the red blood cells become hard, sticky, and change shape, resembling the farm tool.

6 Nov 2023

Low-cost anti-inflammatory hydrogel could help treat chronic skin lesions in people with diabetes

Researchers in São Paulo state, Brazil, have developed a low-cost anti-inflammatory hydrogel that in future could help treat chronic skin lesions such as those often seen in people with diabetes.

27 Oct 2023

New ERC-funded research project aims to develop targeted treatments for chronic wounds and cancer

the Freiburg University Medical Center and member of the Medical Faculty at the University of Freiburg, has received a European Research Council (ERC) Starting Grant from the European Commission.

27 Oct 2023

Red grape polyphenol, resveratrol: a multifaceted therapeutic powerhouse under review

The therapeutic potential of resveratrol, a red grape polyphenol.

25 Oct 2023

Dual-action drug produces shows promising results in neuroendocrine tumor trial

A drug that simultaneously strikes cancer cells' growth circuits and pipeline to the bloodstream produced encouraging results in a clinical trial involving patients with advanced neuroendocrine tumors, according to a study led by Dana-Farber Cancer Institute investigators.

22 Oct 2023

Cracking the code: recent discoveries transform our understanding of cancer-immunity cycle

In a recent review published in Immunity, researchers reviewed tumor-immunity cycle data.

13 Oct 2023