Vasculature News and Research

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MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Pericytes are the primary locus of matrix-mellaproteinase-9-dependent (MMP-9) capillary damage and blood leakage during ischemia, according to preclinical findings reported by Medical University of South Carolina investigators in an article published online on November 14, 2016 by The Journal of Neuroscience.

5 Dec 2016

New hydrogel-based vascular embolization may offer great advantage for treating clotting disorders

Small blood clots called emboli are mostly known for traveling through the vasculature before they lodge and obstruct vessels, impeding blood and oxygen supply to organs like the lung.

16 Nov 2016

Preconsumption of red wine can prevent short-term vascular injury caused by smoking

Drinking red wine is widely regarded as protective against cardiovascular disease. A new report in The American Journal of Medicine found that a glass or two of red wine before lighting up a cigarette can counteract some of the short-term negative effects of smoking on blood vessels.

15 Nov 2016

TSRI study suggests new approach to limit tumor growth by targeting immune system cells

A new study led by scientists at The Scripps Research Institute suggests there may be a way to limit tumor growth by targeting immune system cells called macrophages.

11 Nov 2016

UNC scientists find clue that may help explain why people differ in ability to survive arterial blockages

Researchers at the University of North Carolina School of Medicine have found a major clue that may explain why some people sustain relatively little damage from strokes or heart attacks despite severe arterial blockages.

7 Nov 2016

Improved skin graft process shows promise for treating severe burn wounds

Full thickness skin grafts are the golden standard for treating burn wounds. But most skin grafts for severe burns require a donor, and for large or complicated injury sites, a full thickness skin graft is hard to come by.

31 Oct 2016

Are migraines genetic? An interview with Nick Furlotte

There's a big debate right now in the migraine community around the underlying cause of the disease. The question is whether it is vascular, and has something to do with our vessels, or whether it has to do with our neurons not functioning correctly or misfiring.

26 Sep 2016

ENDRA introduces Nexus 128+ with twice the photoacoustic sensitivity

ENDRA Life Sciences today announced the launch of the Nexus 128+, adding to their preclinical photoacoustic computed tomography (CT) systems that leverage ENDRA’s proprietary 3D imaging technology.

From AXT Pty Ltd 8 Sep 2016

New computer program can predict underlying genomics of ER+ breast cancer

The number of tubules in tumors may predict which women with estrogen receptor positive (ER+) breast cancer will benefit from hormone therapy alone and which require chemotherapy, researchers at Case Western Reserve University have found.

7 Sep 2016

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

6 Sep 2016

Could a light-listening photonics device detect skin disease? An interview with Prof. Vasilis Ntziachristos

Detection of malignant skin alterations is currently aided by optical microscopes such as dermoscopes or optical microscopes. While the latter offers high resolution, it comes with a major disadvantage, just like any other purely microscopic method: it only provides a partial view of the skin due to the low penetration depth.

29 Aug 2016

Research findings point to potential drug targets to improve angiogenesis in diabetes patients

Diabetes heightens the risk of vascular damage to heart and limbs, and impairs the ability to repair damage with new growth of blood vessels, called angiogenesis.

26 Aug 2016

Could nanotechnology turn the cancer cell suicide switch back on? An interview with Professor Dipanjan Pan

Before I explain the discovery, I would take a step back and explain an interesting event that takes place in the cancer cells. Normal cells follow a rapid and irreversible process to efficiently eradicate dysfunctional cells. This is a natural process by which damaged cells commit ‘suicide’. This process is known as apoptosis or programmed cell death.

15 Aug 2016

New bioinspired device could diagnose formation of blood clots

When in dysfunction, the vascular endothelium -- the tissue that lines the blood vessels throughout our body's entire circulatory system -- plays a big role in the development of many human diseases, including diabetes, stroke, heart disease, viral infections and cancer.

9 Aug 2016

BP effects on vasculature begin below hypertensive threshold

Higher systolic blood pressure is associated with increased carotid intima-media thickness even within the normotensive range, research shows.

1 Jul 2016

Researchers engineer revolutionary new approach to combat cancer treatment resistance

Math, biology and nanotechnology are becoming strange, yet effective bed-fellows in the fight against cancer treatment resistance. Researchers at the University of Waterloo and Harvard Medical School have engineered a revolutionary new approach to cancer treatment that pits a lethal combination of drugs together into a single nanoparticle.

24 Jun 2016

Age no barrier to vorapaxar use in ACS

The protease-activated receptor 1 inhibitor vorapaxar offers the same benefits to older and younger patients with non-ST segment elevation acute coronary syndromes, shows further analysis of the TRACER trial.

14 Jun 2016

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that a plant-virus-based carrier successfully delivers a drug in vivo.

9 Jun 2016

Neutral atherosclerosis trial highlights effectiveness of optimal medical therapy

Salsalate has no greater effect than placebo on the progression of coronary artery plaque, show the findings of the randomised TINSAL-CVD trial.

3 Jun 2016

$Sostdc1 gene may play vital role in fracture healing process$

Sostdc1 gene may play vital role in fracture healing process

New identification of a gene involved in the fracture healing process could lead to the development of new therapeutic treatments for difficult-to-heal injuries.

2 Jun 2016