Vasculature News and Research

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How have human organoids been used in research to study SARS-CoV-2?

In a recent review published in the journal Organoids, scientists have presented an overview on the use of human stem cell-derived organoids in understanding functionality and cellular tropism of severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), a deadly beta-coronavirus responsible for the ongoing coronavirus disease 2019 (COVID-19) pandemic.

7 Mar 2022

New 3D model of living brain cancer overcomes a major challenge in tissue engineering

As a potential alternative for drug testing without lab animals, researchers at KTH Royal Institute of Technology developed and successfully tested a 3D model of living brain cancer that surmounts one of the biggest challenges in tissue engineering.

4 Mar 2022

Researchers identify genetic link between lymphatic disorder and stillbirth

In a world first discovery, South Australian researchers have identified a genetic mutation responsible for a lymphatic disorder that may cause stillbirth or severe, chronic disease in affected children.

4 Mar 2022

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

In a recent study an immunoPET technique that the authors were using to analyze SIV was adapted to evaluate the spatiotemporal dynamics of SARS-CoV-2 infection in a rhesus macaque model.

2 Mar 2022

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Johns Hopkins Medicine researchers have developed and tested a new imaging approach they say will accelerate imaging-based research in the lab by allowing investigators to capture images of blood vessels at different spatial scales.

28 Feb 2022

Mapping cells to understand vascular disease

In this interview, we speak to Dr. Ethan Winkler and Dr. Tomasz Nowakowski about their latest research which illustrated the interplay between vascular and immune cells that contributes to brain hemorrhage.

25 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

3D model of living brain cancer developed as a potential alternative for drug testing without animals

23 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

In a recent study posted to the medRxiv* preprint server, an interdisciplinary team of researchers from Toronto, Canada, characterized the markers of endothelial function and developed micro ribonucleic acid (miRNA) expression atlas in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive and -negative patients admitted to the intensive care unit (ICU).

15 Feb 2022

New atlas characterizes immune cells that play a role in hemorrhagic stroke

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.

28 Jan 2022

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Hyaluronic acid, or HA, is a known presence in pancreatic tumors, but a new study from researchers at the University of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.

28 Jan 2022

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

In a new study, researchers discuss the role of calcium signaling pathways as targets of inhibition in potential new antiviral therapeutic pathways for SARS-CoV-2.

20 Jan 2022

Study uncovers new details behind inflammation that promotes cardiovascular disease

High cholesterol and inflammation are key drivers of heart disease, and an inflamed buildup of lipids can cut off the blood supply through a coronary artery to cause a heart attack.

24 Dec 2021

Study measures arterial stiffness in women from wide age range

A study conducted at the University of Jyväskylä in the Faculty of Sport and Health Sciences measured arterial stiffness in women from wide age range.

10 Dec 2021

New therapeutic targets for the treatment and prevention of hypertension, cardiovascular diseases

Cardiovascular diseases are the leading cause of death worldwide. Although the development of these disorders is most commonly associated with lifestyle factors like obesity, increasing evidence suggests that events much earlier in one's life can also play a role.

6 Dec 2021

Vasculature News and Research

How have human organoids been used in research to study SARS-CoV-2?

New 3D model of living brain cancer overcomes a major challenge in tissue engineering

Researchers identify genetic link between lymphatic disorder and stillbirth

Potential of a SARS-CoV-2 immunoPET approach to study COVID-19 dynamics in total body in rhesus macaques

New imaging approach provides a clearer ‘picture’ of blood vessels in health and disease

Mapping cells to understand vascular disease

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

3D model of living brain cancer developed as a potential alternative for drug testing without animals

Researchers create a comprehensive atlas of cerebrovascular cell types

Cardiovascular markers for predicting clinical outcomes in SARS-CoV-2 infection

New atlas characterizes immune cells that play a role in hemorrhagic stroke

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Exploring the potential utility of calcium channel inhibitors in SARS-CoV-2 infection

Study uncovers new details behind inflammation that promotes cardiovascular disease

Study measures arterial stiffness in women from wide age range

New therapeutic targets for the treatment and prevention of hypertension, cardiovascular diseases

New mechanism involved in early melanoma metastasis discovered

Johns Hopkins scientists create a stunning 3D map of blood vessels and stem cells in mouse skull

Inhaled prostacyclin improves oxygenation in acute respiratory distress syndrome patients

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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