Ventricular Septal Defects News and Research

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Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model for guiding immunization and prophylactic treatment of one-year-old infants against RSV infections.

3 Mar 2023

People with congenital heart defect may have worse functional exercise capacity

A common congenital heart defect may reduce your ability to exercise especially as you grow older, regardless of whether it was corrected with surgery or previously deemed too small for treatment, according to research published today in the Journal of the American Heart Association, an open access journal of the American Heart Association.

23 Sep 2020

The impact of maternal diabetes on fetal heart development

Congenital heart disease is the most common birth defect. And even with remarkable advances in care, it remains the leading cause of non-infectious death in infants.

24 Dec 2018

Cardiac imaging during surgery may improve outcomes for children with congenital heart disease

Using cardiac imaging during heart surgery can detect serious residual holes in the heart that may occur when surgeons repair a child's heart defect, and offers surgeons the opportunity to close those holes during the same operation.

19 Dec 2016

Children born with CHD more likely to develop type 2 diabetes in adulthood

Children born with heart disease have an increased risk of developing type 2 diabetes after age 30, according to a new study.

19 Jul 2016

New pediatric heart-defect patches enhance electrical connections between cells

Carbon nanotubes serve as bridges that allow electrical signals to pass unhindered through new pediatric heart-defect patches invented at Rice University and Texas Children's Hospital.

24 Sep 2014

Protein known to promote cancer appears to give blood vessels strength and shape, researchers report

A protein known to promote cancer appears to give the blood vessels strength and shape, researchers report. When yes-associated protein, or YAP, is deleted from vascular smooth muscle cells during development, the protein makes thin-walled blood vessels that over-dilate in response to the usual pressure of blood flow, said Dr. Jiliang Zhou, vascular biologist at the Medical College of Georgia at Georgia Regents University.

25 Mar 2014

Study reveals that more than 14% of pregnant women are prescribed opioids for pain

More than 14 percent of pregnant women were prescribed opioids (narcotics) for pain at some time during their pregnancy, according to a study posted to the online version of Anesthesiology.

13 Feb 2014

Study identifies new potential genetic culprits in origins of congenital heart defects

Mitochondria are the power plants of cells, manufacturing chemical fuel so a cell can perform its many tasks. These cellular power plants also are well known for their role in ridding the body of old or damaged cells.

5 Oct 2013

Scientists now have clues to how GATA4 gene mutation leads to septal defects in babies with CHD

Scientists now have clues to how a gene mutation discovered in families affected with congenital heart disease leads to underdevelopment of the walls that separate the heart into four chambers.

27 Jun 2012

CHOP, Albert Einstein College of Medicine to study genetics of conotruncal defects

The Eunice Kennedy Shriver National Institute of Child Health & Human Development, part of the National Institutes of Health, has awarded researchers at Albert Einstein College of Medicine of Yeshiva University and collaborators at the Children's Hospital of Philadelphia (CHOP) a five-year, $6.7 million grant to study the genetics of both rare and common congenital heart abnormalities known as conotruncal defects.

12 Oct 2011

New insight into most common form of congenital heart disease

Repairing small, seemingly benign holes in a child's heart may be more clinically important than previously thought, as dysfunction could be lurking out of sight. These are the findings from a study conducted by doctors and researchers at Nationwide Children's Hospital and the Ohio State University Medical Center examining a subset of the most common form of congenital heart disease, ventricular septal defect.

14 Sep 2010

Psychotropic medications associated with pediatric ADRs in Denmark: Researchers

Between 1998 and 2007, psychotropic medications were associated with 429 adverse drug reactions in children under 17 in Denmark. Researchers writing in the open access journal BMC Research Notes found that more than half of these were serious and several were birth defects - suggesting that tighter controls on the prescription of psychotropic medications to pregnant women may be required.

23 Jun 2010

Landmark study provides new insight into congenital heart defects

Researchers from the UC San Diego, School of Medicine and colleagues have identified a new gene, ETS-1, that is linked to human congenital heart defects. The landmark study, recently published online in the journal of Human Molecular Genetics, provides important insights into some of the most prevalent forms of congenital heart defects in humans, including ventricular septal defects and potentially hypoplastic left heart syndrome, a uniformly fatal heart abnormality.

18 Dec 2009

By-products of water chlorination linked to birth defects

Drinking water disinfected by chlorine while pregnant may increase the risk of having children with heart problems, cleft palate or major brain defects, according to a study published today in BioMed Central's open access journal Environmental Health.

2 Jun 2008

Morgan Stanley Children's Hospital performs transcatheter pulmonary valve replacement

A breakthrough new procedure may improve quality of life for children and adults with a common type of congenital heart defect that interferes with the body's ability to oxygenate blood through the lungs.

24 Aug 2007

Novel catheter technique for patching holes in the heart

A novel catheter technique for patching holes in the heart may make it possible for many patients to avoid surgery altogether and others to regain enough strength to safely undergo surgical repair at a later date, according to a study reported at the 30th Annual Scientific Sessions of the Society for Cardiovascular Angiography and Interventions.

11 May 2007