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Scientists validate oral vaccine delivery system to combat global health threats

Scientists validate oral vaccine delivery system to combat global health threats

Scientists at The Forsyth Institute and Tufts University have succeeded in describing and validating a unique system of oral vaccine delivery using a common bacteria found in the mouth. [More]
UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

UC Davis researchers uncover complex relationship between p53 and Rbm38 proteins

Scientists have long known the p53 protein suppresses tumors. However, a recent animal study by UC Davis researchers has uncovered a complicated relationship between p53 and another protein, Rbm38, highlighting how the body calibrates protein levels. Too much Rbm38 reduces p53 levels, increasing the risk of cancer. [More]
WSU researchers working on better bone-like materials used in hip and knee replacements

WSU researchers working on better bone-like materials used in hip and knee replacements

Washington State University researchers are working to improve materials used in hip and knee replacements so that they last longer and allow patients to quickly get back on their feet after surgery. [More]
Male hormone testosterone may increase risk of colon cancer

Male hormone testosterone may increase risk of colon cancer

Previous cancer research has revealed that women are less likely than men to suffer from non-sex specific cancers such as cancer of the colon, pancreas and stomach. Scientists theorized that perhaps this trend was due to a protecting effect created by female hormones, such as estrogen, that help prevent tumors from forming. Now, researchers at the University of Missouri have found evidence suggesting that the male hormone testosterone may actually be a contributing factor in the formation of colon cancer tumors. [More]
CUMC researchers devise way to replace torn knee meniscus

CUMC researchers devise way to replace torn knee meniscus

Columbia University Medical Center researchers have devised a way to replace the knee's protective lining, called the meniscus, using a personalized 3D-printed implant, or scaffold, infused with human growth factors that prompt the body to regenerate the lining on its own. [More]
Silvia Jurisson recognized as AAAS Fellow for contributions to cancer research

Silvia Jurisson recognized as AAAS Fellow for contributions to cancer research

Nuclear medicine is the branch of medicine that uses radioactive materials to provide diagnostics and treatments for cancer. Often, standard protocols involve using radioactive isotopes developed to image as well as weaken cancer cells in the body. With more than 30 years of research in radiopharmaceutical chemistry, Silvia Jurisson, a researcher at the University of Missouri, is a world-renowned scientist who continues to develop breakthrough materials used in the detection and treatment of cancer. [More]
Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer HealthCare and the Drugs for Neglected Diseases initiative (DNDi) have signed an agreement under which Bayer will provide the active ingredient emodepside to support DNDi in its effort to develop a new oral drug to treat river blindness (or onchocerciasis). The world's second leading infectious cause of blindness, river blindness is a neglected tropical disease caused by a filarial worm. [More]
MD Anderson study sheds light on miR569 gene

MD Anderson study sheds light on miR569 gene

A genetic misfire called the 3q26.2 amplicon can cause real havoc. In fact, it is among the most frequent chromosomal aberrations seen in many cancers, including ovarian and breast cancers. [More]
New fluorescence-imaging agent could improve diagnosis, guide surgeons during tumor removal

New fluorescence-imaging agent could improve diagnosis, guide surgeons during tumor removal

CEA-Leti and CLARA today announced the development of a new fluorescence-imaging agent that could significantly increase surgeons’ accuracy when removing cancerous tumors. [More]
World-renowned experts to discuss challenges of antibiotic resistance at Murdoch University symposium

World-renowned experts to discuss challenges of antibiotic resistance at Murdoch University symposium

World-renowned experts in the fields of antibiotic resistance will come together at a symposium at Murdoch University to talk about an issue which has the potential to become one of the world’s biggest public health challenges. [More]
Tobacco smoke toxin could increase pain in people with spinal cord injury

Tobacco smoke toxin could increase pain in people with spinal cord injury

A neurotoxin called acrolein found in tobacco smoke that is thought to increase pain in people with spinal cord injury has now been shown to accumulate in mice exposed to the equivalent of 12 cigarettes daily over a short time period. [More]
Study: Selenium compounds appear to have beneficial effect on cancer

Study: Selenium compounds appear to have beneficial effect on cancer

The immune system is designed to remove things not normally found in the body. Cells undergoing change, e.g. precursors of cancer cells, are therefore normally recognised and removed by the immune system. Unfortunately, the different cancer cells contain mechanisms that block the immune system's ability to recognise them, allowing them to freely continue cancer development. [More]
Authors review current progress in developing transgenic pig models for human diseases

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research. [More]
Surgery simulator app: an interview with Jean Nehme

Surgery simulator app: an interview with Jean Nehme

Touch Surgery is a mobile surgical simulation app that allows surgeons to learn and rehearse surgical procedures. It provides a cognitive map for operations on a virtual patient. [More]
Abaxis completes acquisition of QCR & Trio Diagnostics

Abaxis completes acquisition of QCR & Trio Diagnostics

Abaxis, Inc., a medical products company manufacturing point-of-care instruments and consumables for the medical, research, and veterinary markets worldwide and providing reference lab services to the veterinary and research markets in the United States, announced today the completion of a stock purchase agreement to acquire 100% of QCR & Trio Diagnostics Limited, a United Kingdom based distribution organization. [More]
Researchers discover a new way to combat influenza virus infection

Researchers discover a new way to combat influenza virus infection

The influenza virus, like all viruses, is a hijacker. It quietly slips its way inside cells, steals the machinery inside to make more copies of itself, and then -- having multiplied -- bursts out of the cell to find others to infect. [More]
Targeting bacterial motility to combat chronic respiratory disease

Targeting bacterial motility to combat chronic respiratory disease

Mycoplasma gallisepticum causes chronic respiratory disease in birds. The illness particularly affects domestic chicken and turkey flocks. The bacteria are especially life-threatening for the animals when they occur in combination with other infections. In order to control the spread of the disease, poultry farms in the EU must be proven free from Mycoplasma gallisepticum or face being closed. [More]
'Spillover' of henipaviruses into humans underway, study finds

'Spillover' of henipaviruses into humans underway, study finds

Another family of viruses, deadly in some cases, may have already jumped from fruit bats into humans in Africa, according to a study published today in the journal Nature Communications. The study provides the first, preliminary scientific evidence that "spillover" of henipaviruses into human populations is underway. [More]
Light-activated diabetes drug: an interview with Dr David Hodson

Light-activated diabetes drug: an interview with Dr David Hodson

We've known about chemicals that can be light-activated for about five to ten years now. They’ve mainly all been applied to neurons and, more specifically, the retina. Nobody has ever really looked at any tissues outside of the nervous system. [More]
CARLINA, GenBiotech to jointly develop prolonged-release protein formulation for cartilage repair

CARLINA, GenBiotech to jointly develop prolonged-release protein formulation for cartilage repair

CARLINA Technologies, a biotechnology company specialized in the development of nanomedicines, today announces the signing of a collaborative agreement with GenBiotech for the development of a prolonged-release pharmaceutical form of a protein. The resultant protein will be used in bone and cartilage repair. Financial details were not disclosed. [More]