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Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

23 Jun 2022

Buy and bust: When private equity comes for rural hospitals

When the new corporate owners of two rural hospitals suddenly announced they would stop admitting patients one Friday in March, Kayla Schudel, a nurse, stood resolute in the nearly empty lobby of Audrain Community Hospital: "You'll be seen; the ER is open."

15 Jun 2022

Study sheds light on inhibition of awn elongation in sorghum

Over the years, the domestication of grasses like wheat, rice, barley, and sorghum for consumption has resulted in certain modifications to their morphology. One such modification is the partial or complete elimination of the 'awns', which are the bristle- or needle-like appendages extending from the tip of the lemma in grass spikelets.

15 Jun 2022

Genome research explains why oats could be suitable for most people with celiac disease

Ground-breaking new research published in Nature has decoded the genome of oats and explained why the popular cereal could be suitable for most people with coeliac disease and gluten intolerance.

18 May 2022

What impact are ultra-processed diets having on our planet?

In this interview, we speak to Fernanda Marrocos about her latest research that investigated the impacts ultra-processed diets are having on our planet.

21 Apr 2022

Crucial blood tests for celiac disease could help shrink the gap to diagnosis and improve care

The Canadian Celiac Association (CCA) hopes that an Ontario Ministry of Health pilot program which includes providing funding for crucial blood tests for celiac disease will be made permanent, to ensure ongoing screening of the 1 in 117 Ontarians at risk for the autoimmune disorder.

11 Apr 2022

Ultra-processed foods in diets are damaging human and planetary health

A global diet that increasingly includes ultra-processed foods is having a negative impact on the diversity of plant species available for human consumption while also damaging human and planetary health, according to a commentary published in the journal BMJ Global Health.

29 Mar 2022

Uptake of SARS-CoV-2 spike protein in human cerebrovascular cells

A recent study assessed the uptake of SARS-CoV-2 spike protein in human cerebrovascular cells via the lipid raft ganglioside.

24 Mar 2022

Cells self-organize to generate forces that model the shapes of tissues

A team from the UNIGE has demonstrated that cells self-organise to generate forces that model the shapes of our tissues.

12 Feb 2022

Study reveals a widening gender gap in the field of family medicine due to COVID-19

As people transitioned to working from home at the onset of the coronavirus pandemic, journal submissions from academics increased across the board. But a new study from Northwestern University found as men's scholarly productivity increased, women physicians were submitting less.

25 Jan 2022

Specification of fictitious added benefit upon market access of orphan drugs not confirmed

In order to promote the development of drugs for rare diseases (orphan drugs) despite market risks, in Germany they are exempt from the regular benefit assessment procedure introduced in 2011 with the Act on the Reform of the Market for Medicinal Products (AMNOG).

13 Jan 2022

UOC project aims to develop a tool for identifying the best apps that help tackle depression

The latest report of the PAHO (Pan American Health Organization) estimated the prevalence of depression in Spain to be 5.2%, and there is every indication that mental health disorders will increase significantly in the wake of the COVID-19 pandemic.

12 Jan 2022

Texas toughens ban on medication-by-mail abortions with jail time and hefty fine

Texas already had the most restrictive abortion laws in the U.S. — and they just got tougher. On Wednesday, a new law took effect that adds penalties of jail time and a fine of up to $10,000 for anyone who prescribes pills for medication abortions through telehealth or the mail.

6 Dec 2021

Study reveals distinct gut microbial 'signatures' highly responsive to dietary therapy for IBS

People who respond well to the recommended dietary therapy of restricting intake of fermentable carbs for irritable bowel syndrome, or IBS for short, have an abundance of particular types of bacteria in their gut, reveals research published online in the journal Gut.

23 Nov 2021

SARS-CoV-2 protease suppresses host immune response by cleaving NEMO

A recent study conducted by a team of US-based scientists has highlighted a novel function of 3C-like protease of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The protease has been found to cleave a human immune signaling protein called NF-kB Essential Modulator (NEMO) and disrupt the host immune response.

16 Nov 2021

New nutrient profiling system assesses the healthfulness of foods

A scientific team at the Friedman School of Nutrition Science and Policy at Tufts has developed a new tool to help consumers, food companies, restaurants, and cafeterias choose and produce healthier foods and officials to make sound public nutrition policy.

14 Oct 2021

Eating whole grain rye products results in more weight loss than refined wheat diet

Eating whole grain rye products instead of refined wheat alternatives can offer worthwhile health benefits.

12 Oct 2021

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

A new paper shows that human TLR3, TLR7, and TLR8 receptors are activated with naturally occurring RNA, but this is eliminated once modified nucleosides such as m5C, m6A, m5U s2U, or pseudouridine are incorporated.

12 Oct 2021

Antiviral activity of wheat germ Agglutinin against SARS-CoV-2

A new study reports the antiviral activity of WGA against SARS-CoV-2 and its two Variants of Concern - Alpha and Beta.

4 Oct 2021

UVA researchers identify 14 genes that cause obesity

Promising news in the effort to develop drugs to treat obesity: University of Virginia scientists have identified 14 genes that can cause and three that can prevent weight gain. The findings pave the way for treatments to combat a health problem that affects more than 40% of American adults.

1 Oct 2021