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Generation of neoantigenic epitopes after posttranslational modification of Type II collagen by factors present within the inflamed joint

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the joints, which gradually erodes the cartilage and bone.

7 Dec 2005

Physicians slow to prescribe newer heart drugs

An analysis of the treatment received by more than 100,000 heart patients has shown that physicians' prescription practices for drugs proven effective for treating heart disease has shown steady improvement over the past three years, cardiologists at the Duke Clinical Research Institute (DCRI) have concluded.

7 Dec 2005

Getting old? Slowing down? Blame inefficient mitochondria

In mitochondria, the fuel is oxidised and builds up a pressure of hydrogen ions (protons). These force through molecular turbines and enable the cell to generate ATP, an energy unit that can be used throughout the cell.

6 Dec 2005

Australian breast cancer study seeks participants

RMIT University researchers are seeking healthy, postmenopausal women to participate in a study to determine if diet and lifestyle can reduce the risk breast cancer.

6 Dec 2005

Its true - marriage can be bad for your health!

U.S. researchers have yet more proof that an unhappy marriage is bad for your health.

6 Dec 2005

A tipple or two a day will keep you trim

A new study suggests that people who have an alcoholic drink or two a day may have a lower risk of becoming obese than either teetotalers or heavy drinkers.

5 Dec 2005

Caffeine and alcohol addiction similar

According to a new study caffeine loving women with a family history of alcohol abuse will have a hard time kicking the coffee habit when they are pregnant.

5 Dec 2005

That glass of wine or two may not be so good for you!

New research from New Zealand suggests that the health benefits of alcohol are dubious.

5 Dec 2005

Cerebrospinal fluid analysis combined with brain scan predicts Alzheimer's

A combination of brain scanning with a new imaging agent and cerebrospinal fluid (CSF) analysis has left neuroscientists encouraged that they may finally be moving toward techniques for diagnosing Alzheimer's disease before its clinical symptoms become apparent.

5 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Unexpected link between muscular dystrophy and muscle wasting associated with cancer

A new study provides important insight into the mechanisms of a muscle wasting disorder that interferes with treatment for cancer and has a negative impact on patient survival.

5 Dec 2005

Disruption of normal gene interaction linked to schizophrenia

Disruption of the normal interaction between the genes PRODH and COMT contributes directly to major symptoms of schizophrenia by upsetting the balance of the brain chemicals glutamate and dopamine, according to a group of investigators that includes a scientist now at St. Jude Children's Research Hospital.

2 Dec 2005

Schizotypy, creativity and mating success in humans

The more creative a person is, the more sexual partners they are likely to have, according to a pioneering study which could explain the behaviour of notorious womanisers such as poets Lord Byron and Dylan Thomas.

2 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

Childbirth not linked to urinary incontinence

Postmenopausal women who have given birth vaginally do not appear to suffer from urinary incontinence at higher rates than their sisters who have never given birth, according to a University of Rochester Medical Center study published in the December Obstetrics and Gynecology journal.

2 Dec 2005

Bisphenol A (BPA) has been linked to damage in developing brain tissue

The chemical bisphenol A (BPA), widely used in products such as food cans, milk container linings, water pipes and even dental sealants, has now been found to disrupt important effects of estrogen in the developing brain.

2 Dec 2005

Protein target for Parkinson's disease

Researchers at Johns Hopkins' Institute for Cell Engineering (ICE) have discovered a protein that could be the best new target in the fight against Parkinson's disease since the brain-damaging condition was first tied to loss of the brain chemical dopamine.

2 Dec 2005