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Fast decline in insulin sensitivity seen in pre-diabetic South Asians

Fast decline in insulin sensitivity seen in pre-diabetic South Asians

People of south Asian descent who have Type 2 diabetes show a more rapid decline in fasting glucose levels than White individuals even before they develop the disease, new findings from the Whitehall II study suggest. [More]
Reducing insomnia can decrease inflammation, lower risk for chronic disease in older adults

Reducing insomnia can decrease inflammation, lower risk for chronic disease in older adults

Lack of sleep can make you sick. And while everybody has the occasional restless night, for those who suffer from chronic insomnia — some 15 percent of older adults in the United States — that sleep loss can increase the risk for cardiovascular disease, hypertension, weight gain, type 2 diabetes, and even lead to an earlier death. [More]
New market research report on global and Chinese stem cell industry

New market research report on global and Chinese stem cell industry

Research and Markets has announced the addition of the "Global and Chinese Stem Cell Industry Report, 2014-2017" report to their offering. [More]
Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Study suggests potential treatment for cardiovascular disease in people with apoE4 gene variant

Researchers at UT-Southwestern Medical Center have found that the most common variant of the circulating protein apolipoprotein E, called apoE3, helps repair the lining of blood vessels. Individuals with another variant, called apoE4, do not get the benefit of this repair, putting them at higher risk for cardiovascular disease. [More]
Common type of hospital-associated infections can be prevented with vaccine

Common type of hospital-associated infections can be prevented with vaccine

The most common type of hospital-associated infection may be preventable with a vaccine, new research in mice suggests. [More]
Studies explore role of STXBP5 gene in development of cardiovascular disease

Studies explore role of STXBP5 gene in development of cardiovascular disease

Two independent groups of researchers led by Sidney (Wally) Whiteheart, PhD, of the University of Kentucky, and Charles Lowenstein, MD, of the University of Rochester, have published important studies exploring the role that a gene called STXBP5 plays in the development of cardiovascular disease. [More]
Scientists find 23 new genetic variants that increase risk for prostate cancer

Scientists find 23 new genetic variants that increase risk for prostate cancer

In an analysis of genetic information among more than 87,000 men, a global team of scientists says it has found 23 new genetic variants - common differences in the genetic code -- that increase a man's risk for prostate cancer. The so-called "meta-analysis," believed to be the largest of its kind, has revealed once hidden mutations among men in a broad array of ethnic groups comprising men of European, African, Japanese and Latino ancestry. [More]
Scientists develop first blood test to diagnose major adult depression

Scientists develop first blood test to diagnose major adult depression

The first blood test to diagnose major depression in adults has been developed by Northwestern Medicine- scientists, a breakthrough approach that provides the first objective, scientific diagnosis for depression. [More]
Ramucirumab effective second-line option for NSCLC

Ramucirumab effective second-line option for NSCLC

The monoclonal antibody ramucirumab, when added to second-line docetaxel, significantly improves the overall survival of patients with stage IV non-small-cell lung cancer, show the findings of the REVEL trial. [More]
Age confounds relationship between ambulatory and office BP

Age confounds relationship between ambulatory and office BP

The relationship between ambulatory and office blood pressure varies with age, with the likelihood of white-coat hypertension increasing as people get older, a study shows. [More]
‘Reassuring’ findings on microvascular risk in diabetic statin users

‘Reassuring’ findings on microvascular risk in diabetic statin users

Statin treatment prior to diabetes onset does not appear to increase the risk of microvascular disease and may even be protective against some forms, findings from a registry study suggest. [More]
APOC3 gene variant dramatically reduces triglyceride levels in the blood

APOC3 gene variant dramatically reduces triglyceride levels in the blood

Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project's cohort of samples from the general public and demonstrates the power of whole genome sequencing at scale. [More]
UCSD researchers launch phase 1 trial to assess novel monoclonal antibody for CLL patients

UCSD researchers launch phase 1 trial to assess novel monoclonal antibody for CLL patients

Researchers at the University of California, San Diego School of Medicine have launched a phase 1 human clinical trial to assess the safety and efficacy of a new monoclonal antibody for patients with chronic lymphocytic leukemia (CLL), the most common form of blood cancer in adults. [More]
New guidance can help physicians determine best oral blood thinners for patients

New guidance can help physicians determine best oral blood thinners for patients

Physicians around the world now have guidance that can help them determine the best oral blood thinners to use for their patients suffering from blood clots in their veins, thanks to a patient of The Ottawa Hospital who asked his physician a question he couldn't answer. [More]
Study provides empirical evidence of decline in stroke incidence, mortality rates in U.S.

Study provides empirical evidence of decline in stroke incidence, mortality rates in U.S.

Despite the significant reduction in the overall incidence and death rates from strokes in the United States over the past twenty years, more attention needs to be paid to specific age groups, a recent study found. [More]
New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

A recent guideline for using statins to reduce atherosclerotic cardiovascular disease has wavered too far from the simple cholesterol goals that have saved thousands of lives in the past decade, and doesn't adequately treat patients as individuals, experts said today in a national report. [More]
Warwick researchers discover novel drug target for treating postpartum haemorrhage

Warwick researchers discover novel drug target for treating postpartum haemorrhage

Researchers at the University of Warwick have discovered a new target for drugs that could prevent the deaths of thousands of women in the developing world due to heavy blood loss after childbirth. [More]
Milk consumption and dairy may lower blood pressure, CVD risk

Milk consumption and dairy may lower blood pressure, CVD risk

Globally, cardiovascular disease (CVD) claims 17 million lives each year, while complications from high blood pressure take an additional 9.4 million. New research presented by international scientists at the 12th Euro Fed Lipid Congress in Montpellier, France on September 15, 2014, suggests that milk consumption and dairy may play a beneficial role. [More]
Study: Marijuana users may attempt to manage negative moods by using drug

Study: Marijuana users may attempt to manage negative moods by using drug

Adolescents and young adults who smoke marijuana frequently may attempt to manage negative moods by using the drug, according to a study in September's Journal of Studies on Alcohol and Drugs. [More]
3SBio signs exclusive license agreement with JenKem for PEG-irinotecan

3SBio signs exclusive license agreement with JenKem for PEG-irinotecan

3SBio Inc., a leading biotechnology company based in China focusing on researching, developing, manufacturing and marketing biopharmaceutical products, announced today that it has entered into an exclusive license agreement with JenKem Technology Co., Ltd for the development, manufacturing and marketing in Mainland China of PEG-irinotecan, a long-acting polymer-drug conjugate which inhibits topoisomerase I (Topo-I). [More]