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UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

UTHealth scientists identify inhibitory switch to prevent peripheral vascular disease

Millions of people in the United States have a circulatory problem of the legs called peripheral vascular disease. It can be painful and may even require surgery in serious cases. This disease can lead to severe skeletal muscle wasting and, in turn, limb amputation. [More]
Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Phase 3 trial: NEXAVAR tablets fail to meet primary endpoint in HER2-negative breast cancer patients

Bayer HealthCare and Onyx Pharmaceuticals Inc., an Amgen subsidiary, today announced that an investigational Phase 3 trial of NEXAVAR (sorafenib) tablets in patients with advanced breast cancer did not meet its primary endpoint of improving progression-free survival (PFS). [More]
Incisionless TAVR surgery cuts length of hospital stay by 30%

Incisionless TAVR surgery cuts length of hospital stay by 30%

New research from Penn Medicine shows that incisionless transcatheter aortic valve replacement (TAVR) surgery cuts length of hospital stay by 30 percent and has no impact on post-operative vascular complication rates when compared with conventional transfemoral TAVR, which requires an incision in the groin. [More]
Blacks with depression and diabetes receive inadequate mental health treatment

Blacks with depression and diabetes receive inadequate mental health treatment

A new study in General Hospital Psychiatry confirms that Blacks with depression plus another chronic medical condition, such as Type 2 diabetes or high blood pressure, do not receive adequate mental health treatment. [More]
Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

Researchers recommend low carbohydrate diet for Type 1 and Type 2 diabetes

A new study involving researchers from the University of Alabama at Birmingham and other institutions says patients with Type 1 and Type 2 diabetes should eat a diet low in carbohydrates. [More]
Children who experience stress early in life have emotional, physical health problems

Children who experience stress early in life have emotional, physical health problems

Children who have been abused or neglected early in life are at risk for developing both emotional and physical health problems. [More]
$1,000-a-pill hepatitis C drug boosts Gilead's fortunes

$1,000-a-pill hepatitis C drug boosts Gilead's fortunes

Sales of the new hepatitis C drug Sovaldi reached $3.5 billion in the second quarter, putting it on track to become one of the world's best-selling medicines and intensifying concerns about its costs. [More]
Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Protein once seen as promising anti-cancer compound helps to stabilize neural circuits

Researchers at UC San Francisco (UCSF) have discovered that endostatin, a protein that once aroused intense interest as a possible cancer treatment, plays a key role in the stable functioning of the nervous system. [More]
Researchers examine association between ritual circumcision procedure and HSV-1 in infants

Researchers examine association between ritual circumcision procedure and HSV-1 in infants

A rare procedure occasionally performed during Jewish circumcisions that involves direct oral suction is a likely source of herpes simplex virus type 1 (HSV-1) transmissions documented in infants between 1988 and 2012, a literature review conducted by Penn Medicine researchers and published online in the Journal of the Pediatric Infectious Disease Society found. [More]
Researchers working to develop new drugs for treating chronic inflammatory diseases

Researchers working to develop new drugs for treating chronic inflammatory diseases

Science and industry are collaborating to develop future pharmaceuticals for treating chronic inflammatory diseases. The medicines will combat immunological processes that have gone wrong. [More]
Immune system play role in memory impairment associated with chronic epilepsy

Immune system play role in memory impairment associated with chronic epilepsy

Could the body's own immune system play a role in memory impairment and cognitive dysfunction associated with conditions like chronic epilepsy, Alzheimer's dementia and concussions? Cleveland Clinic researchers believe so, based on a study published online by PLOS ONE. [More]
Newcomer among arboviruses: The zika virus

Newcomer among arboviruses: The zika virus

In the group of viruses that includes dengue and chikungunya, a newcomer now has people talking about it. Also originating in Africa, zika was isolated in humans in the 1970s. Several years earlier, only a few human cases had been reported. [More]
Neurosurgeons develop new technologies to perform highly complex brain surgery

Neurosurgeons develop new technologies to perform highly complex brain surgery

In a milestone procedure, neurosurgeons at UC San Diego Health System have integrated advanced 3D imaging, computer simulation and next-generation surgical tools to perform a highly complex brain surgery through a small incision to remove deep-seated tumors. [More]
Study provides insights into interplay among bacteria, viruses and immune system during HIV infection

Study provides insights into interplay among bacteria, viruses and immune system during HIV infection

A new study led by the Translational Genomics Research Institute provides insights into the interplay among bacteria, viruses and the immune system during HIV infection. [More]
New therapeutic interventions that target brain regions can prevent obesity

New therapeutic interventions that target brain regions can prevent obesity

Unlocking the secrets to better treating the pernicious disorders of obesity and dementia reside in the brain, according to a paper from American University's Center for Behavioral Neuroscience. [More]
Oregano and rosemary help lower glucose in blood

Oregano and rosemary help lower glucose in blood

The popular culinary herbs oregano and rosemary are packed with healthful compounds, and now lab tests show they could work in much the same way as prescription anti-diabetic medication, scientists report. [More]
Researchers receive inaugural funding from AHA to prevent heart disease and stroke

Researchers receive inaugural funding from AHA to prevent heart disease and stroke

Researchers and clinicians at UT Southwestern Medical Center are among a small, select group at U.S. universities to receive inaugural funding from the American Heart Association (AHA) for work that takes aim at heart disease and stroke. [More]
Obese people have low endurance, experience excess fatigue in workplace

Obese people have low endurance, experience excess fatigue in workplace

Workplaces may need to consider innovative meethods to prevent fatigue from developing in employees who are obese. Based on results from a new study published in the Journal of Occupational and Environmental Hygiene, workers who are obese may have significantly shorter endurance times when perfroming workplace tasks, compared with non-obese counterparts. [More]
Brown recluse spider bites increases this summer, say toxicologists

Brown recluse spider bites increases this summer, say toxicologists

Vanderbilt medical toxicologists are reporting an increase in patients seen with brown recluse spider bites this summer. [More]
Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

Researchers uncover how malaria parasite becomes resistant to fosmidomycin drug

Researchers have uncovered a way the malaria parasite becomes resistant to an investigational drug. The discovery, at Washington University School of Medicine in St. Louis, also is relevant for other infectious diseases including bacterial infections and tuberculosis. [More]