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Research findings could offer ways of fighting treatment resistance in oesophageal cancer

Research findings could offer ways of fighting treatment resistance in oesophageal cancer

Researchers at Trinity College Dublin have made exciting new findings that could offer a means of fighting resistance to treatment for people with oesophageal cancer. [More]
Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

Synthesized steroid prevents lethal protein buildup in animal model of Parkinson's disease

A synthesized steroid mirroring one naturally made by the dogfish shark prevents the buildup of a lethal protein implicated in some neurodegenerative diseases, reports an international research team studying an animal model of Parkinson's disease. [More]
Functional deficits caused by mini-strokes can last longer than previously thought

Functional deficits caused by mini-strokes can last longer than previously thought

Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy. Not only do individuals with cerebrovascular diseases have a much higher incidence of cortical microinfarcts (mini-strokes), but post-mortem histological and in vivo radiological studies also find that the burden of microinfarcts is significantly greater among people with vascular cognitive impairment and dementia (VCID) than in age-matched, non-demented individuals. [More]
Could pathogen infection really lead to Alzheimer’s?

Could pathogen infection really lead to Alzheimer’s?

New concepts of infectious disease are evolving with the realization that pathogens are key players in the development of progressive chronic diseases that originally were not thought to be infectious. Infection is well-known to be associated with numerous neurological diseases for which... [More]
New research paves way for better strategies to diagnose and manage vascular graft infections

New research paves way for better strategies to diagnose and manage vascular graft infections

A rising prevalence of cardiovascular disease has generated substantial growth in the use of medical implants, such as vascular grafts. [More]
Scientists develop 3-D organoid to unravel immune response during infection

Scientists develop 3-D organoid to unravel immune response during infection

What if you could design an adaptable, biomaterials-based model of an organ to track its immune response to any number of maladies, including cancer, transplant rejection and the Zika virus? The lab of Ankur Singh, assistant professor in the Sibley School of Mechanical and Aerospace Engineering, has asked - and begun to answer - that very question. [More]
Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Molecular pharmacologist granted funding to unravel mechanisms of neuronal communication

Our ability to memorize our first kiss or the last day at school as most other functions of the brain relies on communication between nerve cells at special contacts called synapses, where chemical signals are conveyed from one nerve cells to the next. [More]
Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers have developed the first sensor capable of objectively identifying inflammatory bowel disease (IBD) and distinguishing between its two subtypes. [More]
How does the brain control appetite?

How does the brain control appetite?

Energy balance between energy intake and expenditure in our bodies is important for maintaining energy homeostasis to keep our bodies functioning properly. The appetite determines how much we eat, the energy intake, by communication between the brain and body. [More]
MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

An enzyme that plays an active role in inflammation could be a natural way to suppress tumors and ulcers in the colon that are found in colitis associated cancer (CAC), a type of colorectal cancer that is driven by chronic inflammation, according to a new study. [More]
Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry special issue highlights role of dopamine signaling in schizophrenia

Biological Psychiatry presents a special issue, "The Dopamine Hypothesis of Schizophrenia", dedicated to recent advances in understanding the role of dopamine signaling in schizophrenia. [More]
Two research studies on new molecules could potentially treat Alzheimer's disease

Two research studies on new molecules could potentially treat Alzheimer's disease

This year, results have been published of two significant research studies about molecules that could potentially treat Alzheimer's disease. [More]
Researchers identify mechanism that generates synchronous oscillation in the brain

Researchers identify mechanism that generates synchronous oscillation in the brain

Every time we learn something new, the memory does not only need to be acquired, it also needs to be stabilized in a process called memory consolidation. [More]
Scientists developing magnetic stem cells to fight cancer

Scientists developing magnetic stem cells to fight cancer

Scientists from the Tomsk Polytechnic University's Laboratory of Novel Dosage are developing a technology to control mesenchymal stem cells of patients. [More]
Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Scientists identify sugar molecule that reduces inflammatory response and COPD progression

Using a mouse model, scientists from the RIKEN-Max Planck Joint Research Center for Systems Chemical Biology and a number of other institutes have identified a sugar molecule that reduced the inflammatory response and progress of emphysema, a common component of chronic obstructive pulmonary disease (COPD). [More]
Generative AAE can be radically new way to discover drugs on demand

Generative AAE can be radically new way to discover drugs on demand

Scientists at the Pharmaceutical Artificial Intelligence group of Insilico Medicine, Inc, today announced the publication of a seminal paper demonstrating the application of generative adversarial autoencoders (AAEs) to generating new molecular fingerprints on demand. [More]
TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

TSRI scientists identify microbial natural products as abundant sources of potent anticancer drugs

Scientists from the Florida campus of The Scripps Research Institute have developed an efficient process to rapidly discover new “enediyne natural products” from soil microbes that could be further developed into extremely potent anticancer drugs. [More]
Scientists unravel novel role of signalling protein in common type of liver cancer

Scientists unravel novel role of signalling protein in common type of liver cancer

The most common type of liver cancer, called Hepatocellular carcinoma, is one of the most prevalent tumours worldwide. [More]
Rice bioengineers reveal how heart valves use different strategies to handle oxygen starvation

Rice bioengineers reveal how heart valves use different strategies to handle oxygen starvation

As the valves in a heart stretch with each beat, their cells take in life-giving oxygen. But if the supply is cut off, aortic and mitral valves use different strategies to compensate, according to Rice University scientists. [More]
AXT makes magnetic particle imaging technology available to researchers in Australia

AXT makes magnetic particle imaging technology available to researchers in Australia

AXT is proud to be able to bring another cutting-edge technology to Australia that will help our medical researchers accelerate the rate at which they bring new cures, remedies and therapies to clinical realities. [More]
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