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Research findings offer potential explanation for opioid-induced itching

Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming.

27 Mar 2017

Scientists crack crystal structure of entire ZIKV NS5 protein

Zika virus (ZIKV), which causes Zika virus disease, is spread to people primarily through the bite of an infected Aedes aegypti or Aedes albopictus mosquito. An infected pregnant woman can pass ZIKV to her fetus during pregnancy or around the time of birth. Sex is yet another way for infected persons to transmit ZIKV to others.

27 Mar 2017

Researchers create new approach to reduce risk of dental implant failure

According to the American Academy of Implant Dentistry, 15 million Americans have crown or bridge replacements and three million have dental implants -- with this latter number rising by 500,000 a year.

24 Mar 2017

Research suggests way to reverse age-related and radiation-induced DNA damage

DNA repair is essential for cell vitality, cell survival and cancer prevention, yet cells' ability to patch up damaged DNA declines with age for reasons not fully understood.

24 Mar 2017

Micron Oxford advance their cellular imaging techniques using the super-resolution Nanoimager

Micron Oxford is a collaborative, multidisciplinary bioimaging unit working with biomedical researchers in the Oxford area and beyond, to apply advanced light microscopy imaging techniques to address key biological questions.

24 Mar 2017

Researchers develop robust technique for efficient manufacture of red blood cells

Researchers have generated the first immortalised cell lines which allow more efficient manufacture of red blood cells.

23 Mar 2017

New review addresses mysteries behind ‘good’ HDL cholesterol metabolism

A new review addresses the mysteries behind "good" HDL cholesterol and why boosting its levels does not necessarily provide protection from cardiovascular risk for patients. It appears that augmenting the function of HDL cholesterol, rather than its concentration, is key.

22 Mar 2017

Researchers uncover gene mutation that may provide answers to unexplained female infertility

Researchers at Baylor College of Medicine, Texas Children's Hospital and Rice University have uncovered a gene mutation that may provide answers to unexplained female infertility. The study appears in Scientific Reports, a member of the Nature family of journals.

22 Mar 2017

New Danish research provides structural knowledge of DNA repair complex

New Danish research provides mechanistic insight into how DNA is monitored and repaired if damage occurs. The results may eventually help to improve the treatment of certain types of cancer, as the DNA repair complex provides a mechanism for cancer cells to resist chemotherapy.

21 Mar 2017

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

A research project conducted at the University of São Paulo in Brazil in collaboration with other Brazilian research institutions and abroad has revealed new aspects of the action mechanism of organic hydroperoxide resistance (Ohr) enzyme, which enables several species of bacteria to neutralize oxidizing substances released by the defense system of the host organism, be it a plant or an animal.

21 Mar 2017

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Chemists from Russia and Switzerland created biosafe luminescent nanoparticles for imaging tumors and blood vessels damaged by heart attack or stroke.

21 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

Led by professor Ludo Van Den Bosch, scientists from Belgium, the UK and the US have identified new processes that form protein "clumps" that are characteristic of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD).

17 Mar 2017

TSRI researchers develop novel drug delivery method for treating cancers

Scientists from the Florida campus of The Scripps Research Institute have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors.

16 Mar 2017

University of Liverpool to establish new research centre to accelerate development of novel antibiotics

A state-of-the-art research centre to help accelerate the development of new antibiotics is set to be established by the University of Liverpool.

16 Mar 2017

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Scientists at the IDIBAPS Biomedical Research Institute and at the Institute for Research in Biomedicine lead a study in which they have designed a new strategy to get genetically modified viruses to selectively attack tumor cells without affecting healthy tissues.

16 Mar 2017

Study reveals mechanisms behind increased risk of thrombosis in patients with malignant brain tumours

Patients with malignant brain tumours have an increased risk of thrombosis. Up until now we did not understand the mechanisms behind this.

16 Mar 2017

Novel nanoengineered retinal prosthesis may help restore eyesight

A team of engineers at the University of California San Diego and La Jolla-based startup Nanovision Biosciences Inc. have developed the nanotechnology and wireless electronics for a new type of retinal prosthesis that brings research a step closer to restoring the ability of neurons in the retina to respond to light.

14 Mar 2017

Mayo Clinic researchers discover three new senolytic drugs

Mayo Clinic researchers have uncovered three new agents to add to the emerging repertoire of drugs that aim to delay the onset of aging by targeting senescent cells - cells that contribute to frailty and other age-related conditions.

9 Mar 2017

New computer models could help researchers to better predict side-effects of drugs

New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome

8 Mar 2017

in vitro News and Research

Research findings offer potential explanation for opioid-induced itching

Scientists crack crystal structure of entire ZIKV NS5 protein

Researchers create new approach to reduce risk of dental implant failure

Research suggests way to reverse age-related and radiation-induced DNA damage

Micron Oxford advance their cellular imaging techniques using the super-resolution Nanoimager

Researchers develop robust technique for efficient manufacture of red blood cells

New review addresses mysteries behind ‘good’ HDL cholesterol metabolism

Researchers uncover gene mutation that may provide answers to unexplained female infertility

New Danish research provides structural knowledge of DNA repair complex

Research shows how Ohr enzyme plays central role in bacterial anti-oxidant defense

Chemists develop biosafe luminescent nanoparticles for imaging tumors and blood vessels

Circadian misalignments may favor diabetes development

Scientists identify new toxic pathway for protein aggregates in ALS and FTLD

TSRI researchers develop novel drug delivery method for treating cancers

University of Liverpool to establish new research centre to accelerate development of novel antibiotics

Innovative strategy uses genetically modified viruses to selectively attack tumor cells

Study reveals mechanisms behind increased risk of thrombosis in patients with malignant brain tumours

Novel nanoengineered retinal prosthesis may help restore eyesight

Mayo Clinic researchers discover three new senolytic drugs

New computer models could help researchers to better predict side-effects of drugs

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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