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Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Oregon State University scientists have developed a nanomedicine platform for cancer that can help doctors know which tissue to cut out as well as kill any malignant cells that can't be surgically removed.

21 Dec 2017

Study finds combination therapy as effective strategy to treat ovarian cancers

Researchers at The Wistar Institute have found that combining PARP inhibitors, recently approved for the treatment of BRCA-mutant ovarian cancer, with another small molecule inhibitor was effective to treat ovarian cancers without BRCA1 and BRCA2 gene mutations.

19 Dec 2017

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

The University of Kansas' Center for Molecular Analysis of Disease Pathways, a National Institutes of Health Center of Biomedical Research Excellence, recently earned a second phase of grant funding in the amount of $10.8 million for an additional five years.

19 Dec 2017

Researchers use genomics to advance understanding of Parkinson´s disease

It is widely known that genomics has already begun to influence medicine and that bioinformatics holds the key for developing new medical approaches, but how does medical genomics really work?

19 Dec 2017

Bruker Biospec MRI device installed at The Weizmann Institute of Science

The Weizmann Institute of Science in Rehovot, Israel, today announced the installation of the Biospec® 15.2 Tesla USR™ preclinical ultra-high field magnetic resonance imaging (MRI) instrument from Bruker. The new instrument is installed in the Daniel Wolf building of the Department of Chemical Research, and is used by the MRI Biosensors laboratory, led by Dr. Bar-Shir, and the laboratory of Professor Neeman, to open new frontiers in molecular and microscopic imaging, adding to the team's existing world-class MRI instruments.

From Bruker BioSpin - NMR, EPR and Imaging 19 Dec 2017

TSRI scientists uncover new insights into regulatory network behind axon termination

All things must come to an end. This is particularly true for neurons, especially the extensions called axons that transmit electrochemical signals to other nerve cells. Without controlled termination of individual neuron growth, the efficient and accurate construction of a nervous system is in serious jeopardy.

19 Dec 2017

New device uses fast-moving fluids to insert conductive carbon nanotube fibers into the brain

Rice University researchers have invented a device that uses fast-moving fluids to insert flexible, conductive carbon nanotube fibers into the brain, where they can help record the actions of neurons.

18 Dec 2017

EPFL scientists create gold nanoparticles to combat all viruses

HIV, dengue, papillomavirus, herpes and Ebola - these are just some of the many viruses that kill millions of people every year, mostly children in developing countries. While drugs can be used against some viruses, there is currently no broad-spectrum treatment that is effective against several at the same time, in the same way that broad-spectrum antibiotics fight a range of bacteria.

18 Dec 2017

Study reveals biology behind why muscle stem cells respond differently to aging or injury

A new study led by researchers at Sanford Burnham Prebys Medical Discovery Institute describes the biology behind why muscle stem cells respond differently to aging or injury.

15 Dec 2017

Study: Living Lyme disease bacteria found months after antibiotic treatment

Bay Area Lyme Foundation, a leading sponsor of Lyme disease research in the US, today announced results of two papers published in the peer-reviewed journals PLOS ONE and American Journal of Pathology, that seem to support claims of lingering symptoms reported by many patients who have already received antibiotic treatment for the disease.

14 Dec 2017

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

Caris Life Sciences, a leading innovator in molecular science focused on fulfilling the promise of precision medicine, today announced a data presentation, at the 59th American Society of Hematology Annual Meeting & Exposition in Atlanta, demonstrating the identification of a new mechanism of action to treat non-Hodgkin lymphoma (NHL).

13 Dec 2017

Radiation responsive molecules derived from horse chestnuts aid cancer imaging

Research at The City College of New York shows that cancer imaging can be simplified by a photonic process utilizing molecules derived from horse chestnuts.

12 Dec 2017

Study: Combination targeted therapy has high response rates in AML patients

Initial findings from a multi-national open-label phase Ib study of inhibitory drug therapy for relapsed or refractory acute myeloid leukemia (AML) have demonstrated a complete response in up to 50 percent patients say researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2017

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

An international research team headed by the University of Bern and the Netherlands Cancer Institute has developed 3D cell cultures in which genes can be specifically modified. They allow the study of genes that may cause therapy resistance in breast cancer.

11 Dec 2017

MILabs’ versatile Hybrid OI/CT system installed at Guangdong University of Technology

The Institute of Biomedical and Pharmaceutical Sciences at Guangdong University of Technology in Guangzhou – China, has successfully installed a VECTor5 Hybrid OI/CT system from MILabs.

5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Cancer therapies are designed to kill tumor cells, but produce tumor cell debris in the process. In a study published in The Journal of Experimental Medicine, researchers from Brigham and Women's Hospital and colleagues show that leftover debris can stimulate inflammation and tumor growth, but that molecules called resolvins can block that unwanted inflammatory response.

5 Dec 2017

Malvern Panalytical Announce Efforts Towards a Platform For Protein Aggregation Profiling

Malvern Panalytical announces the launch of a collaborative project which aims to support the development of existing and next generation biopharmaceutical products.

From Malvern Panalytical 4 Dec 2017

Researchers refine method to improve early detection of ovarian cancer

Researchers at Rice University and the University of Texas MD Anderson Cancer Center have refined and, for the first time, run in vivo tests of a method that may allow nanotube-based probes to locate specific tumors in the body.

1 Dec 2017

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Postnova Analytics reports that the Department of Molecular Biology & Biotechnology at the University of Sheffield is using their AF2000 Field Flow Fractionation system to investigate the mechanism of amyloid formation, a protein mis-folding process implicated to be the cause of Alzheimer’s and other neurodegenerative diseases.

From Postnova Analytics 1 Dec 2017

in vivo News and Research

Nanomedicine platform can guide doctors to remove tumors and kill malignant cells

Study finds combination therapy as effective strategy to treat ovarian cancers

KU researchers win $10.8 NIH grant to study cancer, neurological disorders, lung and heart diseases

Researchers use genomics to advance understanding of Parkinson´s disease

Bruker Biospec MRI device installed at The Weizmann Institute of Science

TSRI scientists uncover new insights into regulatory network behind axon termination

New device uses fast-moving fluids to insert conductive carbon nanotube fibers into the brain

EPFL scientists create gold nanoparticles to combat all viruses

Study reveals biology behind why muscle stem cells respond differently to aging or injury

Study: Living Lyme disease bacteria found months after antibiotic treatment

Caris Life Sciences reveals identification of new mechanism of action to treat NHL

Radiation responsive molecules derived from horse chestnuts aid cancer imaging

Study: Combination targeted therapy has high response rates in AML patients

Researchers generate 3D cell cultures to investigate mechanisms of drug resistance in breast cancer

MILabs’ versatile Hybrid OI/CT system installed at Guangdong University of Technology

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

Clearance of cancer cell debris via pro-resolving mediators can prevent tumor recurrence

Malvern Panalytical Announce Efforts Towards a Platform For Protein Aggregation Profiling

Researchers refine method to improve early detection of ovarian cancer

Postnova’s AF2000 FFF system used to unlock mystery of neurodegenerative diseases

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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