The Esprit is designed for high throughput SPR experiments. The automation allows reproducible measurements with the possibility to analyze up to 192 samples without user intervention. The double channel reference measurement can be used to correct for systematic experimental errors and/or modified surfaces matrix effects.
Robotics
The Autosampler is controlled by the liquid handling tools in the data acquisition software. Samples are taken from the microwell plate and directly injected into the cuvette. The automatic control allows the user to run measurements continuously with controllable flow in the cuvette. There are two types of cuvettes, one for lifescience and diagnostics and another for biosensors and chemistry applications.
Cuvette
The cuvette makes recovery of samples part of the advantages of the design. It enables easy flow control and fixed sample volumes for every measurement time scale.
Key Features
| Measuring principle |
Scanning angle SPR |
| Sampling rate |
76 Hz |
| Angle range |
4,000 m° |
| Wavelength |
670 nm |
| Angle resolution |
<0.02 m° |
| RI range |
1.26-1.38 |
| Throughput |
Double channel |
| Detection limit |
180D |
| Ka |
103-107 M-1s-1 |
| Kd |
10-5-10-1 s-1 |
| KD |
104-1010 M-1 |
| Concentration range |
10-11-10-3 M |
| Sample recovery |
by design |
| Sensor disk |
gold coated |