Biochemistry

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Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

A team led by Gang Han, PhD, has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging contrast that can be easily cleared by the body.

10 Jul 2017

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Chemists have long sought to develop new reactions for the direct conversion of simple hydrocarbon building blocks into valuable materials such as pharmaceuticals in a way that dependably creates the same chemical bonds and orientations.

7 Jul 2017

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

While much about Alzheimer's disease remains a mystery, scientists do know that part of the disease's progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons.

6 Jul 2017

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.

6 Jul 2017

Scientists develop new class of pain medication without dangerous side effects

Scientists from Freie Universität Berlin and Charité - Universitätsmedizin Berlin at Campus Benjamin Franklin have developed a new class of pain medication.

4 Jul 2017

Researchers develop new biocompatible materials for soft-tissue adhesion

Researchers at Okayama University describe in Acta Biomaterialia a new type of biocompatible adhesive material. The adhesive, made from nanoparticles of hydroxyapatite, glues both synthetic hydrogels and mouse soft tissue, providing a promising alternative to organic materials currently in use for clinical applications.

30 Jun 2017

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Mitochondria, best known for their role as powerhouses of eukaryotic cells, fulfill numerous vital functions. Knowledge about the precise protein composition as well as the functions of individual proteins is essential to understand fundamental processes of cell biology and diseases that are caused by cellular defects.

29 Jun 2017

Study sheds light on night work−cancer link

A new study has offered insights into the association between night shift work and increased cancer risk, as well as pointing towards a potential solution. For several years, scientists have thought that disruption to the body’s natural circadian rhythm is accountable for the increased cancer risk, but the mechanisms behind this have not yet been pinpointed.

27 Jun 2017

Researchers uncover three-dimensional structure of tetanus toxin protein

"Our discovery could be used to design new medicines", says Pål Stenmark, Associate Professor at the Department of Biochemistry and Biophysics, Stockholm University.

27 Jun 2017

Scientists develop novel enzyme technology that prevents formation of biofilms

Have you ever heard of biofilms? They are slimy, glue-like membranes that are produced by microbes, like bacteria and fungi, in order to colonize surfaces.

22 Jun 2017

CCNY scientists develop rapid method for preparing molecules with potential against HIV

As the HIV/AIDS epidemic approaches its fourth decade, each year brings promising news of pioneering research to alleviate the scourge.

20 Jun 2017

Uniqsis FlowSyn continuous flow reactor helps simplify scale-up of API batch processes

A leading Contract Research and Development Organisation – Arcinova has invested in a Uniqsis FlowSyn™ continuous flow reactor enabling them to develop and simplify the scale-up of a challenging API batch process.

19 Jun 2017

Automated rapid blood test provides accurate malaria diagnosis

Diagnosing malaria has been a very time-consuming and error-prone process up to now. Together with his Dutch colleague Jan van den Boogaart, Professor Oliver Hayden from the Technical University of Munich has now developed an automated rapid blood test that provides an accurate diagnosis in almost 100 percent of cases.

16 Jun 2017

Researchers find flavonoid levels and antioxidant activity to be higher in organic onions

Five years ago, a highly publicized meta-analysis of more than 200 studies concluded that organic food was no more nutritious than conventionally grown food.

15 Jun 2017

Altered virus could help more patients to become eligible for human gene therapy trials

For many patients, participating in gene therapy clinical trials isn't an option because their immune system recognizes and fights the helpful virus used for treatment.

13 Jun 2017

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.

13 Jun 2017

TSRI scientists solve cellular mystery that may have implications for fundamental biology

Scientists at The Scripps Research Institute have solved a cellular mystery that may have important implications for fundamental biology and diseases like ALS.

13 Jun 2017

Scientists find way to recover protein structure after chemical denaturation

Scientists from ITMO University in Saint Petersburg and Hebrew University in Jerusalem have found a way to recover a protein structure after its chemical denaturation.

9 Jun 2017

Biochemistry

Cellular antennae play key role in muscle-to-fat transformation

Targeting acid metabolite reduces size and spread of breast cancer

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Scientists develop new class of pain medication without dangerous side effects

Researchers develop new biocompatible materials for soft-tissue adhesion

Scientists discover, count and determine new mitochondrial proteome in baker's yeast

Study sheds light on night work−cancer link

Researchers uncover three-dimensional structure of tetanus toxin protein

Scientists develop novel enzyme technology that prevents formation of biofilms

CCNY scientists develop rapid method for preparing molecules with potential against HIV

Uniqsis FlowSyn continuous flow reactor helps simplify scale-up of API batch processes

Automated rapid blood test provides accurate malaria diagnosis

Researchers find flavonoid levels and antioxidant activity to be higher in organic onions

Altered virus could help more patients to become eligible for human gene therapy trials

Scientists create method for mapping genome-wide DNA damage caused by chemical carcinogen

TSRI scientists solve cellular mystery that may have implications for fundamental biology

Scientists find way to recover protein structure after chemical denaturation

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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