Biochemistry

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Lactate plays a critical role in helping neural stem cells develop into specialized neurons

Scientists at Tohoku University have discovered the critical role that lactate plays in helping neural stem cells develop into specialized neurons, a process dubbed neuronal differentiation.

24 Jul 2023

New $7 million grant supports research on how environmental chemicals impact gut microbiome

Worldwide, high rates of obesity and other inflammatory conditions are associated with increased risk for cancer, cardiovascular disease and type 2 diabetes.

21 Jul 2023

New compound shows promise in stopping breast cancer metastasis

Researchers from the University of Liverpool have created a biomedical compound that has the potential to stop the spread of breast cancer. A recently published paper details these early findings.

21 Jul 2023

Using single-cell mass spectrometry to study antimicrobial treatment failure

Laura-Isobel McCall, Ph.D., and Zhibo Yang, Ph.D., co-principal investigators and associate professors of chemistry and biochemistry in the Dodge Family College of Arts and Sciences at the University of Oklahoma, have been awarded a prestigious R01 grant from the National Institutes of Health for their project, "Novel single-cell mass spectrometry to assess the role of intracellular drug concentration and metabolism in antimicrobial treatment failure."

19 Jul 2023

Researchers achieve first-ever gram-scale synthesis of tanzawaic acid B

The discovery of antibiotics in 1928 was a major turning point in the history of medicine. For the first time since the dawn of human civilization, doctors had gained access to an extremely powerful and effective tool to fight against a wide variety of bacterial infections.

19 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Scientists discover new mechanism for kidney cell renewal

University of Texas at Dallas scientists have discovered a previously unknown "housekeeping" process in kidney cells that ejects unwanted content, resulting in cells that rejuvenate themselves and remain functioning and healthy.

14 Jul 2023

Plant cell study reveals new role for enzyme in lipid metabolism

A new study by Rice University bioscientists explains how basic cellular structures common to most life forms collaborate to fuel growth in a model plant organism. The findings could shed light on corresponding mechanisms in human cells.

12 Jul 2023

Biomimetic nanocarriers fuse with cell membranes to deliver drugs

In drug delivery, the therapeutic behavior of the nanocarriers is limited by the "foreign" character of their surface.

12 Jul 2023

Novel protein modifies the cellular machinery responsible for producing cellulose in plant cells

Cellulose -; an integral component of plant cell walls -; is an important source of food, paper, textiles and biofuels, but how its creation is regulated within plant cells has remained unclear.

11 Jul 2023

Lollipop-based saliva collection system shows promise for more enjoyable, accurate diagnostic testing

A lollipop might be a sweet reward for a kid who's endured a trip to the doctor's office, but now, this candy could make diagnostic testing during a visit less invasive and more enjoyable.

10 Jul 2023

New insights into the growth dynamics of mineral dendrites

An international research team involving scientists from the University of Vienna, the Faculty of Physics of the University of Warsaw and Univeristy of Edinburgh has described the process of growing three-dimensional manganese dendrites.

10 Jul 2023

Scientists develop breakthrough approach to create artificial allosteric sites in protein complexes

According to a recently published research paper by a team of scientists, a groundbreaking approach has been developed to create artificial allosteric sites (where by binding an effector molecule, activity at the distal active site is regulated) in protein complexes.

6 Jul 2023

Purecap method offers hope for purer and safer mRNA vaccines

A research group from Japan has developed a method to produce highly active mRNA vaccines at high purity using a unique cap to easily separate the desired capped mRNA.

5 Jul 2023

Omega-3 rich oil can prevent damage to honey bee mitochondria caused by pesticides

New research suggests that the use of an omega-3 rich oil called "ahiflower oil" can prevent damage to honey bee mitochondria caused by neonicotinoid pesticides.

4 Jul 2023

High-res insights into key bacterial enzyme could lead to development of new antibiotics

A team of scientists from around the globe, including those from Trinity College Dublin, has gained high-res structural insights into a key bacterial enzyme, which may help chemists design new drugs to inhibit it and thus suppress disease-causing bacteria.

30 Jun 2023

Study reviews the status of microbial succinic acid production

The current status and future perspectives on the successful industrialization of biobased succinic acid are discussed in a comprehensive review article in the peer-reviewed journal Industrial Biotechnology.

30 Jun 2023

Scientists use designer tubulins to crack the tubulin code

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it its shape, and act as tracks for moving molecular cargo around inside the cell.

29 Jun 2023

Researchers develop light-controlled drug delivery system using liposomes

Artificial lipid bilayer vesicle liposomes, also called proteoliposomes, are specialized systems capable of incorporating various molecules, such as chemicals and drugs.

28 Jun 2023

New method could revolutionize the delivery of antioxidants to stem cells

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which presents an issue when trying to maintain cell cultures for therapeutic use.

27 Jun 2023