Cell Biology

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Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Scientists identify signaling pathway in liver cells linked to fibrosis

A healthy liver filters all the blood in your body, breaks down toxins and digests fats. It produces collagen to repair damaged cells when the liver is injured.

25 Apr 2024

New research lays foundation for targeted therapies to inhibit NF-κB activation

A new paper by Dana-Farber Cancer Institute scientists lays the foundation for targeted therapies to inhibit activation of nuclear factor kappa B (NF-κB), a transcription factor that plays a role in various autoimmune and inflammatory diseases and cancers.

25 Apr 2024

Genetically modified mice reveal key players in immune defense against viruses

Chemokines are signaling proteins that orchestrate the interaction of immune cells against pathogens and tumors.

25 Apr 2024

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Researchers at Karolinska Institutet have developed a web-based platform that offers an unprecedented view of the human body at the cellular level.

25 Apr 2024

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Whether human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) could heal luminal ulcers in Crohn’s disease.

25 Apr 2024

Prostaglandin E2: The culprit behind tumor immune evasion

Tumors actively prevent the formation of immune responses by so-called cytotoxic T cells, which are essential in combating cancer. Researchers at the Technical University of Munich (TUM) and the Ludwig-Maximilians-Universität München (LMU) Hospital have now uncovered for the first time how this exactly happens.

24 Apr 2024

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

In a breakthrough for cancer research, scientists at EPFL have created lab-grown mini-colons that can accurately mimic the development of colorectal tumors, offering a powerful new tool for studying and testing treatments for the disease.

24 Apr 2024

Giant virus takes down deadly brain parasite

The single-celled organism Naegleria fowleri ranks among the deadliest human parasites. Researchers around Matthias Horn and Patrick Arthofer from the Center for Microbiology and Environmental Systems Science at the University of Vienna, in an international collaboration, have discovered viruses that infect this harmful microbe.

24 Apr 2024

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

The beginning of life is shrouded in mystery. While the intricate dynamics of mitosis is well-studied in the so-called somatic cells – the cells that have a specialized function, like skin and muscle cells – they remain elusive in the first cells of our bodies, the embryonic cells.

24 Apr 2024

New technique allows scientists to study the fatty contents of cancer cells

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors.

23 Apr 2024

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

23 Apr 2024

Beyond biology: Creating dynamic synthetic cells with programmable DNA

In a new study published in Nature Chemistry, UNC-Chapel Hill researcher Ronit Freeman and her colleagues describe the steps they took to manipulate DNA and proteins -; essential building blocks of life -; to create cells that look and act like cells from the body.

23 Apr 2024

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

23 Apr 2024

Womb pressure shapes facial features, UCL study reveals

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

23 Apr 2024

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Researchers at the University of Arizona College of Medicine – Tucson were awarded a $1.8 million grant by the National Institute of General Medical Sciences, a division of the National Institutes of Health, to learn how human papillomavirus makes its way to a cell's nucleus.

22 Apr 2024

Cells use liquid droplets to regulate signaling pathways, study finds

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

22 Apr 2024

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

Cell Biology

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Scientists identify signaling pathway in liver cells linked to fibrosis

New research lays foundation for targeted therapies to inhibit NF-κB activation

Genetically modified mice reveal key players in immune defense against viruses

Multi-omics approach powers Karolinska Institutet's Single Cell Atlas

Therapeutic potential of human umbilical cord-derived mesenchymal stem cells in Crohn’s disease

Prostaglandin E2: The culprit behind tumor immune evasion

Novel lab-grown mini-colons can accurately mimic the development of colorectal tumors

Giant virus takes down deadly brain parasite

Timelapse breakthrough: Scientists capture secrets of early embryonic cell division

New technique allows scientists to study the fatty contents of cancer cells

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Beyond biology: Creating dynamic synthetic cells with programmable DNA

State-of-the art imaging reveals how lipid metabolism is changed in Alzheimer's disease

Womb pressure shapes facial features, UCL study reveals

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Cells use liquid droplets to regulate signaling pathways, study finds

Study explores the effects of ovulation inducing method on embryo quality

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Top pharmaceutical company evaluates Optimer for precision liver medicine

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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