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Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers develop mouse model to improve basic research on Ebola treatments, vaccines

Researchers at the University of North Carolina at Chapel Hill and colleagues have developed the first genetic strain of mice that can be infected with Ebola and display symptoms similar to those that humans experience. [More]
University of Adelaide-led project develops new test to eradicate H5N1 bird flu

University of Adelaide-led project develops new test to eradicate H5N1 bird flu

A University of Adelaide-led project has developed a new test that can distinguish between birds that have been vaccinated against the H5N1 strain of avian influenza virus or "bird flu" with those that have been naturally infected. [More]
Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

Profectus BioSciences gets funding to develop VesiculoVax Zaire-Ebola virus vaccine

Profectus BioSciences, Inc., a clinical-stage vaccine company developing novel vaccines for the treatment and prevention of infectious diseases, announced today that the Department of Defense through the Medical Countermeasure Systems-Joint Vaccine Acquisition Program, a subordinate command of the Joint Program Executive Office for Chemical and Biological Defense, Edgewood, MD, has contracted the manufacture and IND-enabling preclinical testing of the Profectus trivalent Ebola/Marburg vaccine. [More]
Dosing of antiretroviral medication to prevent HIV infection differs by sex

Dosing of antiretroviral medication to prevent HIV infection differs by sex

A mathematical model developed by NIH grantees predicts that women must take the antiretroviral medication Truvada daily to prevent HIV infection via vaginal sex, whereas just two doses per week can protect men from HIV infection via anal sex. [More]
Google search data can provide more accurate real time picture of flu

Google search data can provide more accurate real time picture of flu

Researchers have found that Google search data really can provide a more accurate real time picture of current flu infections. [More]
Specific complex carbohydrates in human milk protect against Norovirus

Specific complex carbohydrates in human milk protect against Norovirus

Norovirus is the most common cause of viral epidemic gastroenteritis. About 18% of all gastroenteritis infections are caused by Norovirus affecting 267 million people worldwide every year. According to information of the Robert Koch-Institute more than 200.000 Norovirus-infections were registered in Germany during 2012 and 2013. The Centers for Disease Control and Prevention report up to 21 million Norovirus-infections per year in the USA. [More]
Research shows that copper could help to prevent Ebola spread

Research shows that copper could help to prevent Ebola spread

Research from the University of Southampton has indicated that copper could help to prevent the spread of Ebola. [More]
Illicit drug use, tourism contribute to elevated HIV/AIDS risk in the Dominican Republic

Illicit drug use, tourism contribute to elevated HIV/AIDS risk in the Dominican Republic

The Caribbean has the second highest global human immunodeficiency virus (HIV) prevalence in the world outside of Sub-Saharan Africa, with HIV/AIDS as leading cause of death among people aged 20–59 years within the region. Particularly hard-hit are the Dominican Republic (DR) and Haiti, on the island of Hispaniola, accounting for approximately 70% of all people living with HIV in the Caribbean region. [More]

Researchers examine accuracy of GenoType MTBDRslassay for detection of drug-resistant TB

Researchers from the Cochrane Infectious Diseases Group, hosted at LSTM, have conducted an independent review to examine the diagnostic accuracy of the GenoType MTBDRslassay for the detection of resistance to second-line anti-tuberculosis drugs. [More]
NCI supports further clinical development of next-generation HPV vaccine

NCI supports further clinical development of next-generation HPV vaccine

The National Cancer Institute in the USA is supporting the new vaccine developed at the MedUni Vienna against the human papillomavirus (HPV) with at least US$ 3.5 million. This is a major success for the developers and means that the foundations can now be laid for the clinical trials needed for licensing as a vaccine. [More]
Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year. [More]
CHOP, Temple University to jointly investigate new methods for eradicating HIV

CHOP, Temple University to jointly investigate new methods for eradicating HIV

The Children's Hospital of Philadelphia and Temple University have received a joint $4.3 million, four-year grant from the National Institute of Mental Health to investigate new methods to eradicate HIV that lurks in brain cells despite conventional antiviral treatments. [More]

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, economically viable, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options. [More]
ETEC vaccine candidate provides significant protection against bacterial diarrhea

ETEC vaccine candidate provides significant protection against bacterial diarrhea

New results from a safety and immunogenicity study, which included a challenge phase to test efficacy, indicate that a live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine candidate, given in combination with a novel adjuvant, provided significant protection against disease. [More]
Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

Pulmocide uses INTEGRA's VIAFLO Assist pipetting assistant to improve screening of novel compounds

INTEGRA reports on how respiratory drug discovery and development specialists - Pulmocide Ltd. (London, UK) are using a VIAFLO Assist pipetting assistant to enhance the productivity and reproducibility of their screening of novel compounds in a range of biological assays. [More]

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

Positive new clinical data were released today on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute. [More]
Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Imaxio awarded ANR funding to improve efficacy of vaccines for seasonal influenza

Imaxio, a biopharmaceutical company specialized in vaccines, today announces that it has been awarded funding of EUR 600,000 (USD 772,000) by the French National Research Agency (Agence Nationale de la Recherche, ANR) for the OPTIVAC project 'leveraging On t-cell immune resPonse To Improve influenza VACcines'. [More]
Cleaver Scientific helps in UK fight against Ebola

Cleaver Scientific helps in UK fight against Ebola

Cleaver Scientific reports that its horizontal electrophoresis equipment is being used on the frontline of the UK fight against Ebola. [More]

IBM launches initiatives to help curb spread of Ebola in West Africa

IBM has launched several initiatives to help curb the spread of Ebola in West Africa. [More]
Researchers identify compounds that could lead to discovery of new drugs for African sleeping sickness

Researchers identify compounds that could lead to discovery of new drugs for African sleeping sickness

In early drug discovery, you need a starting point, says North­eastern Uni­ver­sity asso­ciate pro­fessor of chem­istry and chemical biology Michael Pollastri. [More]