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Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Tafenoquine, a prodrug that could fulfill the criteria for a mass eradication campaign.

23 Apr 2024

Womb pressure shapes facial features, UCL study reveals

Physical cues in the womb, and not just genetics, influence the normal development of neural crest cells, the embryonic stem cells that form facial features, finds a new study led by UCL researchers.

23 Apr 2024

Scientists map all yeast proteins across cell cycle for the first time

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle. This is the first time that all the proteins of an organism have been tracked across the cell cycle, which required a combination of deep learning and high-throughput microscopy.

23 Apr 2024

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Researchers at the University of Arizona College of Medicine – Tucson were awarded a $1.8 million grant by the National Institute of General Medical Sciences, a division of the National Institutes of Health, to learn how human papillomavirus makes its way to a cell's nucleus.

22 Apr 2024

Cells use liquid droplets to regulate signaling pathways, study finds

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

22 Apr 2024

Young mouse plasma found to reverse aging in older mice

Researchers demonstrate that small extracellular vesicles (sEVs) from young mice plasma can reverse aging effects in older mice by enhancing mitochondrial function and energy metabolism.

22 Apr 2024

Study explores the effects of ovulation inducing method on embryo quality

Low birth rates have become a serious problem in many developed countries throughout the world, with Japan being a prime example. In Japan particularly, aging and stress have led to a massive rise in infertility, which now affects one in every 4.4 couples.

22 Apr 2024

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Dysregulated R-loops can cause stalled replication forks and telomere instability. However, how R-loops are recognized and regulated, is still not well understood, particularly at telomeres.

22 Apr 2024

Top pharmaceutical company evaluates Optimer for precision liver medicine

Optimer delivery vehicle has been shipped to a pharma partner for external evaluation.

From Aptamer Group 22 Apr 2024

Study finds high microplastic levels in Mediterranean fish despite low chemical contaminants

Researchers in a recent study published in the journal Foods discovered high levels of microplastics in popular Mediterranean fish species, despite low levels of cadmium and antibiotics, highlighting ongoing environmental concerns.

19 Apr 2024

Study reveals key protein's role in balancing immune response to viral infections

Researchers have revealed the regulatory mechanism of a specific protein that plays a key role in balancing the immune response triggered by viral infections in mammal cells.

18 Apr 2024

Spatiotemporal transcriptomics reveals insights into primate ovarian aging

The ovary is an essential organ for female fertility, and its age-dependent decline in function is a major cause of infertility.

18 Apr 2024

Researchers receive NIH grant to help develop gene therapy for HIV

Researchers at Washington University School of Medicine in St. Louis have received a $6.2 million grant from the National Institutes of Health (NIH) to develop a gene therapy that would modify the immune system's B cells to spur them to produce broadly neutralizing antibodies against HIV.

18 Apr 2024

Familial environment key factor in metacognition and mentalizing abilities

Twin studies have proven invaluable for teasing out the effects of both genetics and the environment on human biology.

18 Apr 2024

Study explores tocotrienols' neuroprotective effects in obesity-related cognitive decline

Obesity has become a pressing worldwide health issue, with rates steadily rising over recent decades.

18 Apr 2024

New platform can deliver gene therapy precisely to specific areas of the brain

A novel approach to gene therapy is improving lives in ways once thought impossible. Researchers at The Ohio State University Wexner Medical Center and College of Medicine have developed a new platform to deliver the gene therapy precisely to specific areas of the brain.

18 Apr 2024

Life Science News

Innovative malaria prodrug targets liver, enhances efficacy while reducing toxicity, preclinical studies show

Womb pressure shapes facial features, UCL study reveals

Scientists map all yeast proteins across cell cycle for the first time

University of Arizona researchers awarded $1.8M grant to investigate HPV's cellular invasion

Cells use liquid droplets to regulate signaling pathways, study finds

Young mouse plasma found to reverse aging in older mice

Study explores the effects of ovulation inducing method on embryo quality

Protecting telomeres: ILF3 and the regulation of R-loop dynamics

Top pharmaceutical company evaluates Optimer for precision liver medicine

Study finds high microplastic levels in Mediterranean fish despite low chemical contaminants

Study reveals key protein's role in balancing immune response to viral infections

Spatiotemporal transcriptomics reveals insights into primate ovarian aging

Researchers receive NIH grant to help develop gene therapy for HIV

Familial environment key factor in metacognition and mentalizing abilities

Study explores tocotrienols' neuroprotective effects in obesity-related cognitive decline

New platform can deliver gene therapy precisely to specific areas of the brain

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

Discovery of new vascular cell type may pave way for novel strategies to treat cardiovascular diseases

The U.S. Pharmacopeia (USP) and Mestrelab Research, S.L. (Mestrelab)

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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