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Study shows how transcription factor p73 promotes process of producing fertile sperm

Study shows how transcription factor p73 promotes process of producing fertile sperm

The process of producing high-quality, fertile sperm requires many steps. A study in The Journal of Cell Biology shows how the transcription factor p73 promotes this process by regulating the adhesions between developing sperm and their support cells. [More]

Measuring circulating tumor cells may help better predict prostate cancer survival

New research by USC Norris Comprehensive Cancer Center scientists demonstrates that measuring circulating tumor cells (CTCs) - the cells that spread cancer through the body - may be a better predictor of patient survival than the prostate specific antigen (PSA). [More]
Clinical trials of new drugs to treat most aggressive form of prostate cancer

Clinical trials of new drugs to treat most aggressive form of prostate cancer

Clinical trials of new drugs to treat the most aggressive form of prostate cancer are expected to be underway in Brisbane within three years, thanks to Movember Revolutionary Team Award grant that is fast-tracking global research into the disease. [More]
Obesity: fat mass in cells expands with disuse

Obesity: fat mass in cells expands with disuse

Over 35 percent of American adults and 17 percent of American children are considered obese, according to the latest survey conducted by the Centers for Disease Control and Prevention. Associated with diabetes, heart disease, stroke, and even certain types of cancer, obesity places a major burden on the health care system and economy. It's usually treated through a combination of diet, nutrition, exercise, and other techniques. [More]
Consuming alcohol several times a week 'ups' risk of stroke mortality

Consuming alcohol several times a week 'ups' risk of stroke mortality

Consuming alcohol more frequently than twice a week increases the risk of stroke mortality in men, according to a study carried out at the University of Eastern Finland. The results show that the effects of alcohol are not limited to the amount consumed, but also the frequency of drinking matters. The results were published in Acta Neurologica Scandinavica on 8 March. [More]

UL researcher receives €250,000 to investigate Benign Prostatic Hyperplasia

University of Limerick researcher, Dr Niall Kelly was recently awarded in the region of €250,000 by the Health Research Board to investigate a condition called Benign Prostatic Hyperplasia (BPH) which affects 50% of men over the age of 50. [More]

Datamonitor Healthcare: Over half a million prostate cancer incident cases to be diagnosed this year

Over half a million cases of prostate cancer will be diagnosed worldwide in 2014, according to new research from global independent analyst firm Datamonitor Healthcare. [More]
Primary ADT proves ineffective in early stage prostate cancer patients

Primary ADT proves ineffective in early stage prostate cancer patients

A study of more than 15,000 men with early stage prostate cancer finds that those who received androgen deprivation as their primary treatment instead of surgery or radiation did not live any longer than those who received no treatment. [More]
Australians it's time to consider a flu vaccination

Australians it's time to consider a flu vaccination

Although it is still early in the season, NPS MedicineWise is joining other health experts in recommending that people at risk of complications of the flu (influenza) get vaccinated against the illness. [More]
A diet rich in animal protein may protect against age-related decline

A diet rich in animal protein may protect against age-related decline

Elderly individuals who consume higher levels of animal protein may be reducing their risk of physical, social and intellectual decline in the future, show study findings. [More]
Risk-based approach for screening men at increased risk of prostate cancer

Risk-based approach for screening men at increased risk of prostate cancer

The UK needs to invest in testing for those men most at risk of prostate cancer rather than follow a cast-the-net-wide approach targeting the whole population, a leading scientist from The University of Manchester - part of Manchester Cancer Research Centre - has argued at an international conference this week. [More]

Mortality in prostate cancer lower in areas with frequent use of PSA testing

Mortality in prostate cancer is lower in areas with frequent use of PSA testing compared with areas with little testing shows a study published online today in Journal of the National Cancer Institute by researchers from Umeå University, Sweden and Memorial Sloan Kettering Cancer Center, New York, NY, USA. [More]
Men who have poorer cardiovascular fitness at 18 years more often suffer from dementia before 60

Men who have poorer cardiovascular fitness at 18 years more often suffer from dementia before 60

Men who at the age of 18 years have poorer cardiovascular fitness and/or a lower IQ more often suffer from dementia before the age of 60. This is shown in a recent study encompassing more than one million Swedish men. [More]

Biomarkers for bone resorption predict outcomes for men with prostate cancer

Biomarkers for bone formation and resorption predict outcomes for men with castration-resistant prostate cancer, a team of researchers from UC Davis and their collaborators have found. [More]

Scientists identify important step toward shutting down growth of prostate cancer cells

Scientists at UT Southwestern Medical Center have identified an important step toward potentially shutting down the growth of prostate cancer cells. [More]

Study finds long-term reduction in mortality for young men who undergo radical prostatectomy

More than 230,000 men will be diagnosed with prostate cancer this year in the United States, but determining their course of treatment remains a source of considerable debate. A new study by researchers from Uppsala University Hospital, Sweden, Harvard School of Public Health and colleagues—which draws from one of the few randomized trials conducted to directly address this issue—finds a substantial long-term reduction in mortality for men with localized cancer who undergo a radical prostatectomy. [More]
Levels of bisphenol A in men's urine could be marker of prostate cancer

Levels of bisphenol A in men's urine could be marker of prostate cancer

Findings by Cincinnati Cancer Center researchers show that levels of bisphenol A (BPA) in men's urine could be a marker of prostate cancer and that low levels of BPA exposure can cause cellular changes in both non-malignant and malignant prostate cells. [More]

Dendreon plans to make PROVENGE available in Europe

Dendreon Corporation today announced that it plans to make PROVENGE (autologous peripheral blood mononuclear cells activated with PAP-GM-CSF or sipuleucel-T) available in Europe, beginning with Germany and the United Kingdom. [More]

UH scientists working to develop next generation of prostate cancer therapies

A University of Houston scientist and his team are working to develop the next generation of prostate cancer therapies, which are targeted at metabolism. [More]
New prostate cancer screening method combines existing tests to increase accuracy

New prostate cancer screening method combines existing tests to increase accuracy

Northwestern Medicine- is the first health care provider in the country to offer a new non-invasive blood test for prostate cancer that is nearly three times more accurate than the current standard prostate-specific antigen (PSA) blood test. Known as the Prostate Health Index (phi), the new test's accuracy will effectively remove the need for many men who test positive for elevated PSA levels to undergo a biopsy to achieve a reliable diagnosis. [More]