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The News-Medical.Net "Thought Leaders" series is a selection of articles written by national and international experts and trusted advisers in health and medicine. All the articles are written by experts who have been invited as recognised leaders in their fields to provide a "state of the art" contribution.
Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Protein M: an interview with Rajesh Grover, PhD, senior staff scientist, Lerner laboratory, TSRI

Protein M is a cell surface protein from Mycoplasma Genitalium that binds to all human antibodies. [More]
Understanding autism: an interview with Roberto Fernández Galán, PhD, Assistant Professor, Case Western Reserve School of Medicine

Understanding autism: an interview with Roberto Fernández Galán, PhD, Assistant Professor, Case Western Reserve School of Medicine

Autism does not come in just one flavour. It is a spectrum of disorders that share several features: impaired social interactions; impaired verbal and non-verbal communication; and restricted, repetitive behaviours. [More]
How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

How do people become depressed? An interview with Anna Watters and Professor Lea Williams, University of Sydney

A clinical diagnosis of depression (i.e. major depressive disorder) is currently defined on the basis of reported symptoms. [More]
Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Valproic acid metabolism and obesity: an interview with Dr. Namandjé Bumpus, Johns Hopkins Medicine

Valproic acid is one of the most widely prescribed drugs for the treatment of epilepsy. It has also been shown to be effective for the treatment of mood disorders and migraine headaches. [More]
Prions and their shadow proteins: an interview with Dr Jiri Safar, Co-Director of the National Prion Disease Pathology Surveillance Center

Prions and their shadow proteins: an interview with Dr Jiri Safar, Co-Director of the National Prion Disease Pathology Surveillance Center

The prion diseases were originally discovered by Dr Gajdusek and Dr Gibbs. The first disease discovered was Kuru, which was affecting native tribes in the Papua New Guinea highlands in the 1950s. [More]
Communication for people with impaired speech: an interview with Professor Mark Hawley, Professor of Health Services Research, Director of CATCH and lead researcher for VIVOCA

Communication for people with impaired speech: an interview with Professor Mark Hawley, Professor of Health Services Research, Director of CATCH and lead researcher for VIVOCA

There are many different causes of speech impairment but the one we are particularly interested in is actually the most common cause of speech impediment, which is dysarthria. [More]
Psoriasis registry: an interview with Dr. Andrew D. Robertson, Chief Scientific and Medical Officer, National Psoriasis Foundation

Psoriasis registry: an interview with Dr. Andrew D. Robertson, Chief Scientific and Medical Officer, National Psoriasis Foundation

Psoriasis is the most common autoimmune disease in the US, affecting 2 to 3% of all Americans. What causes psoriasis in any one individual will stem from a mixture of their genetic background and their environment. [More]
Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Addressing antibiotic resistance: an interview with Professor Otto Cars, Uppsala University, Sweden

Antibiotic resistance is a consequence of antibiotic use. Bacteria adapt to the threat of antibiotics using mechanisms to overcome the drug. These bacteria, which we call resistant bacteria, then survive. [More]
REM sleep, memory and depression: an interview with Dr Penny Lewis, University of Manchester

REM sleep, memory and depression: an interview with Dr Penny Lewis, University of Manchester

Usually you don’t go into REM until you’ve passed through all the other stages of sleep. The stage immediately before REM is slow-wave sleep. [More]
Anxiety, depression and meditation: an interview with Dr Madhav Goyal, Johns Hopkins University School of Medicine

Anxiety, depression and meditation: an interview with Dr Madhav Goyal, Johns Hopkins University School of Medicine

We wanted to be broadly inclusive of any kind of meditation program, so we defined a meditation program to be any kind of structured meditation program that involved at a minimum 4 hours of training, with instructions to practice outside the classroom. [More]
Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Childhood brain cancer (ETMR/ETANTR): an interview with Dr. Nada Jabado, Department of Pediatrics at McGill University

Embryonal tumours with multilayered rosettes (ETMR) are rare, deadly brain tumours that affect mainly children below the age of 4 years. There are 300 cases reported but probably there are many more as this tumour is often misdiagnosed. [More]
Smoking and cancer: an interview with Dr. Lewis Foxhall, VP of Health Policy, University of Texas MD Anderson Cancer Center

Smoking and cancer: an interview with Dr. Lewis Foxhall, VP of Health Policy, University of Texas MD Anderson Cancer Center

The report Smoking and Health: Report of the Advisory Committee to the Surgeon General, identified tobacco as the predominant cause of lung cancer in men. This was the first widely disseminated report based on scientific studies showing the clear link between smoking tobacco and serious health conditions including cancer, chronic lung diseases and heart disease. [More]
Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass and cardiovascular disease risk: an interview with Dr. Brethauer, Cleveland Clinic

Gastric bypass surgery is a type of bariatric operation that results in weight loss and stimulates metabolic effects that treat diabetes and other cardiovascular risk factors such as diabetes, high cholesterol, and hypertension. [More]
C. parvum and cryptosporidiosis: an interview with Dr. Momar Ndao, McGill University

C. parvum and cryptosporidiosis: an interview with Dr. Momar Ndao, McGill University

Cryptosporidium parvum is one of the most common enteropathogens to affect humans in the world. The protozoan parasite causes a gut infection referred to as cryptosporidiosis. [More]
Crowdsourcing fungal metabolites with antitumor activity: an interview with Dr. Robert H. Cichewicz, University of Oklahoma

Crowdsourcing fungal metabolites with antitumor activity: an interview with Dr. Robert H. Cichewicz, University of Oklahoma

Fungi have played a large role in the development of many important drugs that are in wide use today. The most well-known of these are the penicillins. [More]
The fight against HIV/AIDS: an interview with Dr. Mit Philips, HIV/AIDS Policy Analyst, Médecins Sans Frontières (MSF)

The fight against HIV/AIDS: an interview with Dr. Mit Philips, HIV/AIDS Policy Analyst, Médecins Sans Frontières (MSF)

People mainly speak about the progress in HIV/AIDS. We at MSF know and are very conscious of the fact that there has been enormous progress, but the progress is very uneven. [More]
Chronic pain amongst different ethnic groups: an interview with Professor Martin Underwood, Warwick Medical School

Chronic pain amongst different ethnic groups: an interview with Professor Martin Underwood, Warwick Medical School

Conventionally chronic pain is defined as pain that lasts beyond the expected period of healing. Most experts consider a pain to be chronic after three months. [More]
HIV self-test screening strategy: an interview with Dr. Nitika Pant Pai, McGill University

HIV self-test screening strategy: an interview with Dr. Nitika Pant Pai, McGill University

Conventional health facility based HIV testing is plagued with poor rates of testing and has been around for the past 15+ years. Further, about 40-60% of individuals tested in facilities are lost to follow up. [More]
HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

HIV stigma: an interview with Dr. Vargas-Jackson, M.D. Howard University Hospital

Stigma has been defined as a social opportunistic disease that attaches to many illnesses and increases morbidity and mortality rates. Stigma is the shame or disgrace attached to illnesses and diseases regarded as socially unacceptable. [More]
Auditory processing disorder diagnosis: an interview with Dr Doris-Eva Bamiou, UCL Ear Institute

Auditory processing disorder diagnosis: an interview with Dr Doris-Eva Bamiou, UCL Ear Institute

It is a listening or hearing disorder, which is due to the brain’s defective analysis of sounds, so that individuals who are affected with this disorder cannot make sense of what they hear. [More]