Metabolomics News and Research

Latest Metabolomics News and Research

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Metabolomics and multi-omics perspective of cancer show promise for finding new treatments

While cancer is a genetic disease, the genetic component is just one piece of the puzzle -; and researchers need to consider environmental and metabolic factors as well, according to a research review by a leading expert at the University of Alberta.

22 Apr 2022

Consumption of healthy plant-based foods linked with lower risk of developing type 2 diabetes

New research published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]) finds that the consumption of healthy plant-based foods, including fruits, vegetables, nuts, coffee, and legumes, is associated with a lower risk of developing type 2 diabetes (T2D) in generally healthy people and support their role in diabetes prevention.

10 Apr 2022

Decisive role of PDK1 enzyme in acute myeloid leukemia revealed

Acute myeloid leukemia (AML) remains harder to treat therapeutically due to the high existing genetic heterogeneity not only between patients but also between the population of subclones of cancer cells within the same person.

30 Mar 2022

Tuberculosis perturbs epigenetic processes to promote premature cellular aging

Tuberculosis (TB) is a potentially serious infectious disease caused by a type of bacterium called Mycobacterium tuberculosis.

24 Mar 2022

Researchers identify microbial cooperation as one of the causes of drug tolerance

The treatment of fungal infections is often hampered by fungal pathogens that do not respond, or are tolerant, against anti-fungal drugs.

23 Mar 2022

Metabolomic profiling reveals adrenal suppression due to inhaled corticosteroid treatment for asthma

Inhaled cortical steroids (ICS) can help patients manage asthma symptoms, and recent updates to asthma treatment guidelines have expanded recommended, low-dose treatment.

21 Mar 2022

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Researchers investigate innate and adaptive immune responses at both the early and late stages of SARS-CoV-2 infection.

17 Mar 2022

Study reveals the oncometabolite role of progesterone in advanced prostate cancer

In a study published in Cell Reports Medicine, a group of Chinese scientists revealed the oncometabolite role of progesterone in advanced prostate cancer and strategies to eliminate its oncogenic effect as an aspect of prostate cancer treatment.

15 Mar 2022

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

Simultaneous measurement of dozens of types of fats in the blood ("lipidomics") can predict the risk of developing type 2 diabetes (T2D) and cardiovascular disease (CVD) years in the future, according to a new study publishing March 3rd in the open-access journal PLOS Biology from Chris Lauber of Lipotype, Germany, and colleagues.

3 Mar 2022

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

Researchers from different countries performed a meta-analysis of real-world cross-cohorts and provided an association of the gut microbiome with immune checkpoint inhibitors response in patients with advanced melanomas.

2 Mar 2022

AI and machine learning could improve cancer diagnosis through biomarker discovery

Artificial intelligence (AI), deep learning (DL), and machine learning (ML) have transformed many industries and areas of science.

1 Mar 2022

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

Determining the cause of death is one of the most crucial and challenging parts of a forensic investigation.

28 Feb 2022

Novel mechanism that connects circadian rhythm and muscle repair discovered

Northwestern Medicine investigators have discovered a novel mechanism that connects circadian rhythm-controlled cellular metabolism and regeneration with muscle repair after injury, according to recent findings published in the journal Genes and Development.

28 Feb 2022

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Melanoma, a type of skin cancer, is often curable when detected and treated in its early stages. However, the disease can rapidly spread to other organs in the body and become deadly. According to the American Cancer Society, more than 7,600 people die of the disease each year in the United States.

17 Feb 2022

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

A Ludwig Cancer Research preclinical study has demonstrated that a common weight-loss diet could enhance the efficacy of chemotherapy for pancreatic cancer.

12 Feb 2022

Study uncovers a class of microbial enzymes that drive ulcerative colitis

Ulcerative colitis, a subtype of inflammatory bowel disease, is a chronic ailment of the colon affecting nearly one million individuals in the United States. It is thought to be linked to disruptions in the gut microbiome -; the bacteria and other microbes that live inside us -; but no existing treatments actually target these microorganisms.

2 Feb 2022

NIH-funded study will use machine learning to predict individual responses to diet

A new federally funded study will use machine learning to predict how an individual responds to a given diet, allowing physicians to offer patients personalized nutrition prescriptions to improve health and treat chronic diseases.

20 Jan 2022

Mediterranean diet linked to lower mortality in adults over 65

A greater adherence to the Mediterranean diet which had been assessed through an index made with biomarkers during a 20-year scientific monitoring is associated with a lower mortality in adults over 65.

20 Jan 2022

NIH Common Fund supports Nutrition for Precision Health study

The National Institutes of Health is awarding $170 million over five years, pending the availability of funds, to clinics and centers across the country for a new study that will develop algorithms to predict individual responses to food and dietary routines.

20 Jan 2022

Metabolomics News and Research

Latest Metabolomics News and Research

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Metabolomics and multi-omics perspective of cancer show promise for finding new treatments

Consumption of healthy plant-based foods linked with lower risk of developing type 2 diabetes

Decisive role of PDK1 enzyme in acute myeloid leukemia revealed

Tuberculosis perturbs epigenetic processes to promote premature cellular aging

Researchers identify microbial cooperation as one of the causes of drug tolerance

Metabolomic profiling reveals adrenal suppression due to inhaled corticosteroid treatment for asthma

Immuno-metabolomic signatures that correlate with antigen-specific-T cell response during active COVID-19

Study reveals the oncometabolite role of progesterone in advanced prostate cancer

Lipidomic profiling may provide early prediction of type 2 diabetes and cardiovascular disease risk

Study explores signature gut microbiome connection with immune checkpoint inhibitor response in advanced melanomas

AI and machine learning could improve cancer diagnosis through biomarker discovery

Metabolites could be used as biomarkers for forensic diagnosis of diabetes mellitus

Novel mechanism that connects circadian rhythm and muscle repair discovered

Novel blood biomarkers can potentially predict melanoma patients' response to immunotherapy

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

Study uncovers a class of microbial enzymes that drive ulcerative colitis

NIH-funded study will use machine learning to predict individual responses to diet

Mediterranean diet linked to lower mortality in adults over 65

NIH Common Fund supports Nutrition for Precision Health study

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