Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Performance Testing of CytoFLEX Flow Cytometer

This article talks about the performance testing of CytoFLEX Flow Cytometer.

From Beckman Coulter Life Sciences - Flow Cytometry 8 Apr 2015

Spectra of Lidocaine Using EFT NMR

Lidocaine is a widely used local anesthetic and anti-arrhythmic drug with an immediate onset of action.

From Anasazi Instruments, Inc. 31 Mar 2015

Using EFT NMR to Determine Spectra of Propyl benzoate

Propyl benzoate or benzoic acid propyl ester is a naturally occurring, organic chemical compound found in clove stems and sweet cherry.

From Anasazi Instruments, Inc. 31 Mar 2015

EFT-90 Spectra of Ibuprofen Organic Molecules

Ibuprofen (C13H18O2), previously named (RS)-2-(4-(2-methylpropyl)phenyl)propanoic acid, contains the molecular fragments propionic, iso-butyl and phenyl.

From Anasazi Instruments, Inc. 31 Mar 2015

Advantages of Using Eft NMR Spectrometer in Teaching Laboratories

Nuclear magnetic resonance (NMR) spectroscopy is a research technique that exploits the magnetic properties of atomic nuclei to determine the chemical and physical characteristics of the molecules or atoms containing them.

From Anasazi Instruments, Inc. 29 Mar 2015

3D Super-Resolution Microscopic Technique for Whole Cell Imaging

This article discusses using a 3D super-resolution microscopic technique for whole cell imaging.

From Andor Technology Ltd. 10 Mar 2015

SPIM for the Imaging of Biological Samples

Prototype systems used in developmental biology use a wide range of transgenic animals.of imaging apparatus.

From Andor Technology Ltd. 10 Mar 2015

Using Nuclear Magnetic Resonance for Complete Analysis of New Psychoactive Substances

Increasing amounts of new psychoactive substances (NPS) are being developed every year under non-regulated conditions. A major concern is that such substances can be bought legally by consumers, which not only poses unknown health risks, but also represents a significant challenge to both medical and law enforcement personnel.

From Bruker BioSpin - NMR, EPR and Imaging 10 Mar 2015

Combining NIR Spectroscopy and Machine Vision for Rapid Grain Inspection

Gluten, a protein composite found in wheat and related grains such as barley and rye, gives a chewy and elastic texture to dough. Gluten causes health problems in people suffering from celiac disease or gluten intolerance. In these individuals, even a small amount of gluten can cause bowel dysfunction, abdominal pain, debilitating bloating and fatigue, as well as many non-abdominal symptoms.

From Ocean Insight 25 Feb 2015

Measurement of Protein Molecular Weight and Size Using Viscotek SEC-MALS 20 Detector and Waters Empower® SEC System

Biopharmaceuticals are made from proteins and other biological molecules. The protein’s aggregation state and molecular weight often define how active it is. The technique of light scattering is becoming increasingly more common as a means of measuring a protein’s molecular weight, aggregates and oligomers. SEC-MALS testing is one of the more well-established light scattering methods for measuring proteins.

From Malvern Panalytical 28 Jan 2015

Using Differential Scanning Calorimetry to Expedite the Development of Optimized Therapeutic Protein Formulations

During the development of biopharmaceuticals, decision has to be made at the outset whether a biopharmaceutical will be delivered in powder or liquid form. To that end, both powder and liquid formulations have their own advantages and disadvantages. End user convenience is also another factor that has to be taken into account.

From Malvern Panalytical 27 Jan 2015

NMR in Biology: An Overview

Nuclear magnetic resonance spectroscopy (NMR) is a sophisticated research technique used to obtain detailed information about the structure, dynamics, reaction state, and chemical environment of molecules.

From Bruker BioSpin - NMR, EPR and Imaging 21 Jan 2015

Phenom Scanning Electron Microscope Accelerates Blood Clotting Research

Blood clotting or coagulation is a complex process. Researchers at the Maastricht University and Synapse spin-off are conducting fundamental studies and developing practical detection techniques for bleeding and thrombosis. A complete picture of the clotting process will enable scientists to gain a better insight into this unique phenomenon.

From Thermo Fisher Scientific Phenom-World BV 14 Jan 2015

Using DLS Deconvolution Algorithms to Acquire Intensity Weighted Particle Size Distribution from Measured Correlogram

Dynamic light scattering techniques are used to determine particle size distributions of protein therapeutic formulations. In DLS-based measurement, scattering intensity changes are associated across small time spans that produce a correlogram.

From Malvern Panalytical 21 Dec 2014

Overview of Key Principles of Dynamic Light Scattering

Dynamic light scattering (DLS) is generally utilized to determine the particle size distribution of protein therapeutic formulations and other similar bioformulations.

From Malvern Panalytical 18 Dec 2014

Influence of Concentration Effects and Particle Interactions on DLS Analysis of Bioformulations

Dynamic light scattering (DLS) is a technique used to determine particle size distributions of bioformulations. Traditionally, DLS measurements have been used for studying dilute solutions, but contemporary DLS instruments can help in measuring diffusion coefficient of samples at high concentrations and high turbidity.

From Malvern Panalytical 18 Dec 2014

Accurate Assessment of Solid Fat Content Using minispec Benchtop TD-NMR System

Unilever specializes in supplying fast-moving consumer goods and has a collection of over 20,000 patents and patent applications. However, the need for precise assessment of solid fat content and for fast and robust evaluation of safety and quality specifications, present significant challenges.

From Bruker BioSpin - NMR, EPR and Imaging 14 Dec 2014

10 Tips for Successful ChIP Result Using Chromatrap® Technology

In quantitative analyses, the quality of the chromatin prepared is an important factor that determines whether a ChIP assay is successful. The three main aspects of chromatin preparation are lysis, fixation and shearing, with each of these needing to be fully optimized.

From Chromatrap® - Porvair Sciences Ltd 4 Dec 2014

Isolation of High-Quality Chromatin Using Chromatrap® Enzymatic Shearing Kit

Chromatin immunoprecipitation or ChIP is a useful method for studying interactions between DNA and proteins, and therefore improves understanding of gene regulation mechanisms.

From Chromatrap® - Porvair Sciences Ltd 4 Dec 2014

Comparison of DNA Quantification and Characterization Techniques

The quantification and characterization of DNA is often regarded as a laborious process in bioscience laboratories. A number of companies are therefore offering a variety of off the-shelf products for quantifying DNA. This article outlines some of the basic products that are commonly used for the quantification and profiling of DNA.

From Chromatrap® - Porvair Sciences Ltd 4 Dec 2014