Arthritis & Rheumatology News and Research

Latest Arthritis & Rheumatology News and Research

The horrors of TMJ: Chronic pain, metal jaws, and futile treatments

A TMJ patient in Maine had six surgeries to replace part or all of the joints of her jaw.

4 Apr 2024

Systemic Inflammation Index: A new hope for autoimmune disease management

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases.

2 Apr 2024

Atomic-level structural models of enzymes provide disease insights

When nucleic acids like DNA or RNA build up in a cell's cytoplasm, it sets off an alarm call for the immune system.

2 Apr 2024

Researchers develop tool to identify osteoarthritis pain in horses

Morris Animal Foundation-funded researchers introduced a straightforward questionnaire to help horse owners identify and monitor signs of osteoarthritis pain in their equine companions.

2 Apr 2024

New insights into adrenal gland tumor formation

Researchers from Kyushu University's Faculty of Medical Sciences report on new insights into the mechanisms of how adrenal gland tumors are formed.

2 Apr 2024

Fasting's potential in fighting cognitive decline needs more human trials

Despite promising animal studies on fasting and caloric restrictions for neurodegenerative diseases, human clinical trials are scarce, underscoring the need for more research to validate these interventions for cognitive decline.

2 Apr 2024

New insights into the exacerbation of psoriasis through specific genetic defects

The inflammatory potential of tissue-resident regulatory T cells in a murine gain of function model.

27 Mar 2024

Columbia researchers secure $38.95 million ARPA-H contract to build a living knee replacement

A team of researchers from Columbia University Irving Medical Center and Columbia Engineering has been awarded up to a $38.95 million contract from the Advanced Research Projects Agency for Health (ARPA-H) to build a living knee replacement from biomaterials and human stem cells, including a patient's own cells.

26 Mar 2024

New project aims to engineer live joints for osteoarthritis treatment

About 32.5 million people in the United States and 500 million globally suffer from the degenerative joint disease known as osteoarthritis (OA), according to the Centers for Disease Control.

26 Mar 2024

ANU scientists uncover gene mutation driving psoriasis and psoriatic arthritis

Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis – a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body.

25 Mar 2024

Study highlights global fertility decline and its implications for the future

The world is approaching a low-fertility future. Although by 2100 more than 97% of countries and territories will have fertility rates below what is necessary to sustain population size over time, comparatively high fertility rates in numerous low-income countries, predominantly in western and eastern sub-Saharan Africa, will continue to drive population increases in these locations throughout the century.

21 Mar 2024

Investigational gene therapy shows promise for rare childhood neurodegenerative disease

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health.

20 Mar 2024

Risk factors for serious inflammatory conditions in IBD patients identified

Investigators at Cedars-Sinai have identified risk factors that make inflammatory bowel disease (IBD) patients susceptible to developing serious conditions in other parts of their bodies.

20 Mar 2024

Empowering women through self-care: A leap towards health equity

The potential of self-care interventions to improve the health and well-being of girls and women to promote equity, gender equality, and human rights.

20 Mar 2024

Genetic key to milder COVID: Certain genes slash severity and death risk in older men

Study found that certain genetic variants in the IL1RN gene significantly reduce COVID-19-related inflammation and mortality in patients, with notable improvements observed in older men carrying specific single-nucleotide variants.

19 Mar 2024

Discovering the on-switch for rare genetic inflammatory diseases

University of Queensland researchers have discovered how the 'on-switch' for the body's inflammation machinery can get stuck and cause rare genetic inflammatory diseases.

18 Mar 2024

Gout not just for Victorians: 1 in 40 Brits have this extremely painful disease

If you thought gout was an outdated condition affecting portly, red-faced Victorians, think again.1 in 40 Brits now have this extremely painful disease, making it the UK’s most common form of inflammatory arthritis. Cases among people in their 20s and 30s have increased by 30%, and faster monitoring and treatment is needed, says a leading expert.

18 Mar 2024

99mTc-maraciclatide holds potential as a non-invasive test for early-stage endometriosis

The presentation summarized the preliminary findings from patients with known or suspected endometriosis who were imaged with a SPECT-CT camera and subsequently underwent planned laparoscopic surgery, a key-hole surgical procedure to establish the presence, absence and location of endometriotic lesions.

15 Mar 2024

Anti-inflammatory gene variant shields men under 75 from severe COVID-19

A certain variant of a key anti-inflammatory gene protects men under age 75 from severe illness and death when hospitalized from COVID-19, a genetic analysis of their blood shows.

14 Mar 2024

LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024