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Researchers uncover a novel way platelets can suppress inflammation

Platelets are probably best known for their role in blood clotting, making scabs and related, if less salubrious, contributions to heart attacks and strokes. But these tiny, saucer-shaped blood cells have other physiological duties as well, including surveillance for viral or bacterial infections, the recruitment of immune cells to the site of a suspected incursion, and even the direct destruction of pathogens.

18 Aug 2025

Detecting diabetes risk by analyzing household data

New research to be presented at the 2025 Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (September 15-19, 2025) shows that early detection of individuals at risk for diabetes is possible by analyzing the electronic records of people living within the same household for risk factors. The study is led by Dr Tainayah Thomas, Stanford University, Palo Alto, CA, USA, and colleagues.

18 Aug 2025

New therapies for acute kidney injury show promise

Acute kidney injury (AKI) is a severe renal disorder affecting approximately 10%-15% of hospitalized patients and up to 50% in intensive care units (ICUs). Its pathogenesis involves complex inflammatory regulatory mechanisms. As core components of the cytokine network, interleukins (ILs) exert pleiotropic effects in AKI development, extensively participating in inflammation, fibrosis, tissue injury repair, and remote organ damage.

18 Aug 2025

Study links COVID-19 infection to accelerated blood vessel aging in women

A Covid infection, particularly in women, may lead to blood vessels aging around five years, according to research published in the European Heart Journal on 18th August, 2025.

18 Aug 2025

New AAV gene therapy reverses age-related macular degeneration

Neovascular age-related macular degeneration (nAMD) is a progressive eye disease characterized by choroidal neovascularization and subretinal hemorrhage and exudation, leading to vision impairment. Current first-line treatment for nAMD are anti-VEGF agents, which has shown promising therapeutics outcomes.

18 Aug 2025

Off-label ketamine use for chronic pain lacks scientific basis

The off-label use of ketamine to treat chronic pain is not supported by scientific evidence, a new Cochrane review has found.

18 Aug 2025

Can turmeric/curcumin help with weight control in diabetes?

Curcumin/turmeric supplements modestly reduced body weight, waist size, fat mass, and hip circumference in people with type 2 diabetes. Benefits were also seen in prediabetic individuals, especially with longer use and high-absorption formulations.

18 Aug 2025

Can ginger help diabetes? Major review says yes, it lowers blood sugar and inflammation effectively

A new systematic review of five meta-analyses confirms that ginger significantly reduces inflammation, lowers blood sugar and HbA1c in type 2 diabetes, and improves antioxidant status. It also effectively reduces nausea in pregnancy, though its impact on vomiting is less consistent.

17 Aug 2025

Amino acid metabolism shapes the tumor immune microenvironment and therapy response

The tumor microenvironment is not just a site of cancer growth—it is a high-stakes metabolic contest where tumor and immune cells vie for limited resources.

17 Aug 2025

Electrophysiology-based strategies enhance cancer immunotherapy

Tumor electrophysiological abnormalities, characterized by membrane potential dysregulation, ion channel network remodeling, and microenvironmental signaling interactions, are critical drivers of malignancy.

17 Aug 2025

Newly discovered biological pathway explains clotting risk in people with type 2 diabetes

New research from the Charles Perkins Centre at the University of Sydney has uncovered a new biological pathway that may help explain why people with type 2 diabetes are more prone to developing dangerous blood clots, potentially paving the way for future treatments that reduce their cardiovascular risk.

17 Aug 2025

Stem-like peripheral helper T cells found to sustain inflammation in rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease that affects millions worldwide and can have a devastating impact on patients' lives.

17 Aug 2025

RUNX1C isoform identified as driver of chemoresistance in acute myeloid leukemia

One of the biggest challenges in cancer treatment is that certain cancers reappear after chemotherapy-and an aggressive type of blood cancer called acute myeloid leukemia (AML) is notorious for this.

17 Aug 2025

Gut neurons drive immune responses through adrenomedullin 2

Neurons in the gut produce a molecule that plays a pivotal role in shaping the gut's immune response during and after inflammation, according to a new study by Weill Cornell Medicine investigators.

17 Aug 2025

Weill Cornell Medicine leads $14.9 million effort to develop personalized HIV cures

A multi-institutional team led by Weill Cornell Medicine has received a five-year, $14.9 million grant from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, to find ways to remove latent HIV from the cells of individuals with HIV.

17 Aug 2025

New insights into how multisensory integration happens in the brain

It has long been understood that experiencing two senses simultaneously, like seeing and hearing, can lead to improved responses relative to those seen when only one sensory input is experienced by itself.

17 Aug 2025

Alzheimer’s gene risks differ by ancestry, major study reveals 133 new variants

Researchers used whole-genome sequencing from diverse populations to identify 156 variants, including 133 novel ones, linked to Alzheimer’s disease and related dementias. The study highlights ancestry-specific genetic risk and protective factors, challenging one-size-fits-all approaches to dementia genetics.

17 Aug 2025

Study shows probiotics help preterm babies fight antibiotic-resistant bacteria

Researchers found that probiotics help reduce antibiotic-resistant bacteria in the guts of very-low-birth-weight preterm infants, but cannot fully prevent resistance genes from spreading. Antibiotic use still promotes gene swapping, highlighting the limits of probiotics alone in neonatal care.

17 Aug 2025

Community pop-up screenings uncover hidden cardiovascular risk factors

Pop-up screening for atherosclerotic cardiovascular disease (ASCVD) risk held at community pharmacies and large-scale sporting events can identify people with uncontrolled cardiovascular risk factors, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand.

17 Aug 2025

Genetically-engineered immune cells show promise for preventing organ rejection

A Medical University of South Carolina team reports in Frontiers in Immunology that it has engineered a new type of genetically modified immune cell that can precisely target and neutralize antibody-producing cells complicit in organ rejection.

17 Aug 2025