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‘Neuroprotective’ effects of smoking disputed

‘Neuroprotective’ effects of smoking disputed

The apparent neuroprotective effect of smoking may simply be because ease of quitting smoking is a marker of prodromal Parkinson’s disease, say researchers. [More]
Vascular receptor autoantibodies implicated in SSc-PAH

Vascular receptor autoantibodies implicated in SSc-PAH

medwireNews: Autoantibodies to endothelin receptor type A and angiotensin receptor type-1 predict the development of, and mortality from, systemic sclerosis-associated pulmonary arterial hypertension, research suggests. [More]
HRQoL goals may improve outcome in PAH

HRQoL goals may improve outcome in PAH

Health-related quality of life before and during treatment for pulmonary arterial hypertension is significantly associated with survival, Brazilian researchers report. [More]
Changing placebo response dilutes antipsychotic trial power

Changing placebo response dilutes antipsychotic trial power

Factors including patients’ expectations may underlie an increased placebo response in antipsychotic randomised controlled trials published since 1960, say researchers. [More]
Verbal abuse worsens bipolar disease outcome

Verbal abuse worsens bipolar disease outcome

Experiencing verbal abuse in childhood has a lasting negative effect on the course of bipolar disorder, researchers have found. [More]
Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

Study identifies new signaling pathway that leads to inflammatory bone erosion in RA patients

A new study by researchers at Hospital for Special Surgery identifies a new signaling pathway that contributes to the development and progression of inflammatory bone erosion, which occurs in patients with rheumatoid arthritis (RA). Rheumatoid arthritis is a systemic inflammatory autoimmune disease that affects millions of adults worldwide. [More]
Rutgers scientists are developing new medical imaging method for early detection of cancer

Rutgers scientists are developing new medical imaging method for early detection of cancer

A new medical imaging method being developed at Rutgers University could help physicians detect cancer and other diseases earlier than before, speeding treatment and reducing the need for invasive, time-consuming biopsies. [More]
Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Novel 'designer' nanodevice could improve cancer diagnostics, treatment

Cancer diagnostics and treatment options could be drastically improved with the creation of a 'designer' nanodevice being developed by researchers from the UK, Italy, the US and Argentina. [More]
Walnuts may help prevent Alzheimer's disease, study finds

Walnuts may help prevent Alzheimer's disease, study finds

A new animal study published in the Journal of Alzheimer's Disease indicates that a diet including walnuts may have a beneficial effect in reducing the risk, delaying the onset, slowing the progression of, or preventing Alzheimer's disease. [More]
Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Analgesics, anti-inflammatory drugs have beneficial effect on treatment of depression

Ordinary over the counter painkillers and anti-inflammatory drugs purchased from pharmacies may also be effective in the treatment of people suffering of depression. [More]
Novel way for treating non-cardiac chest pain due to esophageal hypersensitivity

Novel way for treating non-cardiac chest pain due to esophageal hypersensitivity

Chest pain doesn't necessarily come from the heart. An estimated 200,000 Americans each year experience non-cardiac chest pain, which in addition to pain can involve painful swallowing, discomfort and anxiety. Non-cardiac chest pain can be frightening for patients and result in visits to the emergency room because the painful symptoms, while often originating in the esophagus, can mimic a heart attack. [More]
Marital hostility, history of depression can increase obesity risk in adults

Marital hostility, history of depression can increase obesity risk in adults

The double-whammy of marital hostility and a history of depression can increase the risk for obesity in adults by altering how the body processes high-fat foods, according to new research. [More]
Innovative treatment option for children with plastic bronchitis

Innovative treatment option for children with plastic bronchitis

A case study published recently in the journal Pediatrics describes an innovative, minimally invasive procedure that treated plastic bronchitis, a potentially life-threatening disease, in a six-year-old boy with a heart condition. Using new lymphatic imaging tools and catheterization techniques, physician-researchers eliminated bronchial casts, which are an accumulation of lymphatic material that clogged the child's airway. [More]
Research: MHCI protein moonlights in nervous system to regulate synapses

Research: MHCI protein moonlights in nervous system to regulate synapses

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function. [More]
The Jackson Laboratory gets $10M to build new center for genomics and computational biology

The Jackson Laboratory gets $10M to build new center for genomics and computational biology

The Jackson Laboratory announced today that technology investor David Roux and his wife Barbara have gifted $10 million to support research and find cures for genetically based diseases. [More]
Maternal nutrition before conception important to improve offspring’s health, say researchers

Maternal nutrition before conception important to improve offspring’s health, say researchers

Researchers from the Medical Research Council Lifecourse Epidemiology Unit, University of Southampton, believe the key to making future generations healthier could lie before the mother becomes pregnant. [More]
Higher level of vocabulary can help combat cognitive impairment

Higher level of vocabulary can help combat cognitive impairment

Some people suffer incipient dementia as they get older. To make up for this loss, the brain's cognitive reserve is put to the test. [More]
Cypher researchers identify new genetic cause of severe epileptic encephalopathy

Cypher researchers identify new genetic cause of severe epileptic encephalopathy

Cypher Genomics, Inc., the genome informatics company, announced today the identification of de novo KCNB1 missense mutations as a novel genetic cause of severe epileptic encephalopathy. Cypher’s co-founder and Chief Scientific Officer Ali Torkamani, Ph.D. reviewed the data today at a platform presentation at the ASHG 2014 meeting being held October 18 to 22 in San Diego. [More]
Scientists identify potent inhibitors to combat common obesity gene

Scientists identify potent inhibitors to combat common obesity gene

Individuals who are genetically predisposed to obesity may soon have a therapeutic solution to combat their condition. A research team led by scientists from the National University of Singapore (NUS) has identified several potent inhibitors that selectively target FTO, the common fat mass and obesity-associated gene. [More]
Researchers find frequency, severity of medication errors among young children

Researchers find frequency, severity of medication errors among young children

According to Nationwide Children's Hospital researchers, 63,000 children under the age of six experienced out-of-hospital medication errors annually between 2002 and 2012. One child is affected every eight minutes, usually by a well-meaning parent or caregiver unintentionally committing a medication error. [More]