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Artificial intelligence unlocks new frontiers in RNA drug design

In the realm of modern medicine, RNA-based therapies have emerged as a promising avenue, with significant advancements in metabolic diseases, oncology, and preventive vaccines. A recent article published in Engineering titled "The Future of AI-Driven RNA Drug Development" by Yilin Yan, Tianyu Wu, Honglin Li, Yang Tang, and Feng Qian, explores how artificial intelligence (AI) can revolutionize RNA drug development, addressing current limitations and offering new opportunities for innovation.

31 Dec 2025

Viruses on plastic waste pose new antibiotic resistance risks

Plastic pollution does more than litter landscapes and oceans. According to a new perspective article published in Biocontaminant, viruses living on plastic surfaces may play an underrecognized role in spreading antibiotic resistance, raising concerns for environmental and public health worldwide.

31 Dec 2025

Novel method can generate functional organoids from human adult adipose tissue

A recent study published in Engineering has unveiled a novel approach to generating functional organoids from human adult adipose tissue.

30 Dec 2025

Study sheds new light on the role of NSUN2 protein in cardiac hypertrophy and heart failure

A recent study published in Engineering has shed new light on the role of the protein NSUN2 in the development of cardiac hypertrophy and heart failure.

30 Dec 2025

New computational method reconstructs how cells decide their fate

Researchers from Kyushu University have developed an innovative computational method, called ddHodge, that can reconstruct the complex dynamics of how cells decide their fate.

30 Dec 2025

Silica nanomatrix enhances immunotherapy for solid tumors

Cancer has long remained a leading cause of death worldwide and in Hong Kong, accounting for 30% of all disease-related deaths in the city in 2025. While chemotherapy remains a major treatment modality, its side effects and the risk of relapse challenges for patients.

30 Dec 2025

Targeting CSE enzyme may offer new pathways for Alzheimer’s treatment

Scientists at Johns Hopkins Medicine say results of a new National Institutes of Health-funded study are advancing efforts to exploit a new target for Alzheimer's disease: a protein that manufactures an important gas in the brain.

30 Dec 2025

Epigenetic clocks accurately predict age from human skeletal muscle

A new research paper was published in Volume 17, Issue 11 of Aging-US on November 26, 2025, titled "Epigenetic aging signatures and age prediction in human skeletal muscle."

30 Dec 2025

Dihydrotanshinone I induces autophagic cell death in ovarian cancer

A recent study published in Engineering has shed light on the potential therapeutic effects of dihydrotanshinone I (DHT), a compound derived from the traditional Chinese herb Salvia miltiorrhiza, on ovarian cancer.

30 Dec 2025

Euphorbia neriifolia L. extract protects against cardiomyocyte injury and heart failure

Announcing a new publication for Acta Materia Medica journal. Heart failure (HF) remains a major global health challenge with limited therapeutic options, thus prompting the search for novel cardioprotective agents among traditional Chinese medicines.

30 Dec 2025

Biomimetic brain modeling mirrors animal learning and neural dynamics

A new computational model of the brain based closely on its biology and physiology not only learned a simple visual category learning task exactly as well as lab animals, but even enabled the discovery of counterintuitive activity by a group of neurons that researchers working with animals to perform the same task had not noticed in their data before, said a team of scientists at Dartmouth College, MIT, and the State University of New York at Stony Brook.

30 Dec 2025

Periodontal bacterial load associated with disease severity in multiple sclerosis

Increasing evidence suggests that the severe gum disease, periodontitis, may contribute to central nervous system disorders through chronic inflammation.

30 Dec 2025

Minimal residual disease monitoring can transform breast cancer care

Despite major therapeutic advances, breast cancer remains prone to recurrence, particularly in patients with early-stage disease who appear disease-free after treatment.

30 Dec 2025

Immune cell energy metabolism shapes the progression of atherosclerosis

Two complementary studies reveal how an insufficient supply of energy in macrophages, key immune cells in artery walls, drives the progression of atherosclerosis - and how this knowledge could lead to better diagnostics and future therapies.

30 Dec 2025

Advancing stem cell regeneration through animal-free culture systems

Intestinal Stem Cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for treating intractable intestinal diseases due to their low risk of rejection.

30 Dec 2025

Epigenetic plasticity in germinal center B cells may help explain lymphoma origins

Immune cells called B cells make antibodies that fight off invading bacteria, viruses and other foreign substances. During their preparation for this battle, B cells transiently revert to a more flexible, or plastic, stem-cell-like state in the lymph nodes, according to a new preclinical study from Weill Cornell Medicine investigators.

30 Dec 2025