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New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

New three-dimensional map of cystic fibrosis protein offers new insights to treating fatal disease

Rockefeller scientists have created the first three-dimensional map of the protein responsible for cystic fibrosis, an inherited disease for which there is no cure. [More]
Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells. [More]
Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Protective barrier inside chromosomes helps prevent errors during cell division, study finds

Fresh insights into the structures that contain our genetic material could explain how the body's cells stay healthy. [More]
New study finds genetic link between Parkinson's disease and cognitive decline

New study finds genetic link between Parkinson's disease and cognitive decline

Although the hallmark symptoms of Parkinson's disease (PD) - such as involuntary shaking, slowness of movement and muscle rigidity - are related to movement, recent evidence has suggested that memory impairment plays an outsized role in diminished quality of life and the burden placed on caregivers. [More]
Study suggests new approach to treat white blood cells of sepsis patients

Study suggests new approach to treat white blood cells of sepsis patients

New research findings published in the Journal of Leukocyte Biology, suggest that treating the white blood cells of sepsis patients with antibodies that block programmed cell death-1 (PD-1) and programmed cell death ligand (PD-L1) molecules may restore their function and ultimately their ability to eradicate deadly bacteria. [More]
OHSU scientists identify potential target for preventing and treating Alzheimer's disease

OHSU scientists identify potential target for preventing and treating Alzheimer's disease

A new scientific discovery may provide a future avenue for treatment and prevention of Alzheimer's disease. [More]
USP researchers develop new platform to detect 416 viruses from  tropical regions

USP researchers develop new platform to detect 416 viruses from tropical regions

Researchers from the University of São Paulo at Ribeirão Preto in Brazil have developed a platform that analyzes clinical samples from patients to diagnose infection by 416 viruses found in the world's tropical regions. [More]
Duke researchers modify popular drug-delivery technology to evade immune responses

Duke researchers modify popular drug-delivery technology to evade immune responses

Biomedical engineers at Duke University have reconfigured a popular drug-delivery technology to evade immune responses that have halted some clinical trials. [More]
Transcranial magnetic stimulation could bring back abandoned memories

Transcranial magnetic stimulation could bring back abandoned memories

It's clear that your working memory -- which holds attention on small things of short-term importance -- works, or you wouldn't be able to remember a new phone number long enough to dial it. [More]
Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Bone density could be one of early indicators of brain degeneration in Alzheimer's disease

Researchers at NEOMED have just identified a major connection between areas of the brainstem - the ancient area that controls mood, sleep and metabolism - and detrimental changes to bone in a preclinical model of Alzheimer's disease (AD). [More]
Researchers develop efficient computational method to create new drugs

Researchers develop efficient computational method to create new drugs

Researchers of the University of Barcelona have developed a more efficient computational method to identify new drugs. [More]
TSRI scientists discover potential drug candidate to suppress pain and itch

TSRI scientists discover potential drug candidate to suppress pain and itch

In a new study, scientists from the Florida campus of The Scripps Research Institute have identified a possible drug candidate that suppresses pain and itch in animal models. [More]
Researcher explores link between PTSD and repeated alcohol use

Researcher explores link between PTSD and repeated alcohol use

As families gather for the holidays this year, many will reminisce, sharing fond memories as they break bread and pass the cranberry sauce. [More]
Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread. [More]
Study identifies conditions required to further develop liver and pancreas cells

Study identifies conditions required to further develop liver and pancreas cells

AMSBIO reports on the recent publication in Nature Protocols1 by Dr Meritxell Huch** and co-workers which describes development of culture conditions that allow the long-term expansion of adult primary tissues from the liver and pancreas into self-assembling 3D organoid cultures. [More]
No link exists between maternal flu and increased child autism risk, says study

No link exists between maternal flu and increased child autism risk, says study

A study has found no association between a mother catching the flu during pregnancy and their child having an increased risk of autism spectrum disorder (ASD). [More]
How old is your heart?

How old is your heart?

There have been a number of ways to measure the biological health and age of your heart, which has been done conventionally in the past. Blood pressure is one indicator. Other risk indicators include family history of heart disease, level of cholesterol and exercise testing, where you can get heart rate... [More]
Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods publishes comparative study of leading Protein-Protein Interaction Networks

Nature Methods published (online) a comparative study of leading Protein-Protein Interaction (PPI) Networks. [More]
New mouse model provides key information for understanding cortical circuit development

New mouse model provides key information for understanding cortical circuit development

A day by day log of cortical electric activity in the mouse visual cortex was published in the Journal of Neuroscience by George Washington University researcher Matthew Colonnese, Ph.D. [More]
Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers uncover new prognostic marker and possible therapeutic target for Ewing's sarcoma

Researchers of the Sarcoma research group of the Bellvitge Biomedical Research Institute, led by Dr. Òscar Martínez-Tirado, have first described the methylation profile of Ewing's sarcoma, a cancer of bone and soft tissues that mainly affects children and teenagers. [More]
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