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Scientists find 23 new genetic variants that increase risk for prostate cancer

Scientists find 23 new genetic variants that increase risk for prostate cancer

In an analysis of genetic information among more than 87,000 men, a global team of scientists says it has found 23 new genetic variants - common differences in the genetic code -- that increase a man's risk for prostate cancer. The so-called "meta-analysis," believed to be the largest of its kind, has revealed once hidden mutations among men in a broad array of ethnic groups comprising men of European, African, Japanese and Latino ancestry. [More]
Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Rosuvastatin promotes bone growth in mice with achondroplasia symptoms

Skeletal dysplasia is a group of rare diseases that afflict skeletal growth through abnormalities in bone and cartilage. Its onset hits at the fetal stage and is caused by genetic mutations. [More]
TSRI scientists devise new vancomycin-based antibiotic to rout resistant bacteria

TSRI scientists devise new vancomycin-based antibiotic to rout resistant bacteria

Scientists at The Scripps Research Institute have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria. [More]
Sigma-Aldrich enters into new gene editing partnership with U-M Medical School's Vector Core

Sigma-Aldrich enters into new gene editing partnership with U-M Medical School's Vector Core

Sigma-Aldrich Corporation announced today it has entered into a new gene editing partnership with the University of Michigan Medical School's Vector Core. Under the partnership, Sigma-Aldrich will provide the Vector Core with Sigma CRISPR technology, experimental design consultation, and dedicated gene editing bioinformaticians. [More]
Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Researchers discover new molecular mechanism that plays crucial role in age-dependent diabetes

Ageing of insulin-secreting cells is coupled to a progressive decline in signal transduction and insulin release, according to a recent study by researchers at Karolinska Institutet in Sweden. [More]
Jacobsen syndrome linked to autism, find UCSD and SDSU researchers

Jacobsen syndrome linked to autism, find UCSD and SDSU researchers

A rare genetic disorder known as Jacobsen syndrome has been linked with autism, according to a recent joint investigation by researchers at San Diego State University and the University of California, San Diego. In addition to suggesting better treatment options for people with Jacobsen syndrome, the finding also offers more clues into the genetic underpinnings of autism. [More]
Study uncovers new genetic risk factor for deadly skin cancer

Study uncovers new genetic risk factor for deadly skin cancer

Buffers that guard against damage to the ends of chromosomes could hold the key to a better understanding of malignant melanoma - the deadliest form of skin cancer - according to new research from the University of Leeds. [More]
ICO-IDIBELL researchers identify 5 genes differentially expressed in colorectal tumors

ICO-IDIBELL researchers identify 5 genes differentially expressed in colorectal tumors

Researchers at the Catalan Institute of Oncology-Bellvitge Biomedical Research Institute, led by David Garcia-Mollev- have identified 5 genes differentially expressed in normal accompanying cells in colorectal tumors. [More]
APOC3 gene variant dramatically reduces triglyceride levels in the blood

APOC3 gene variant dramatically reduces triglyceride levels in the blood

Research using data collected from around 4,000 healthy people in the UK has enabled scientists to identify a rare genetic variant that dramatically reduces levels of certain types of lipids in the blood. The study is the first to emerge from the UK10K Project's cohort of samples from the general public and demonstrates the power of whole genome sequencing at scale. [More]
Researchers gain new knowledge about complex processes that cause Parkinson's disease

Researchers gain new knowledge about complex processes that cause Parkinson's disease

Using advanced computer models, neuroscience researchers at the University of Copenhagen have gained new knowledge about the complex processes that cause Parkinson's disease. The findings have recently been published in the prestigious Journal of Neuroscience. [More]
NIH awards grant to scientist to link drugs, genes and diseases

NIH awards grant to scientist to link drugs, genes and diseases

The National Institutes of Health wants to make the process of finding new drugs faster and better. The effort will help all 27 of its research institutes and centers. So, the nation's medical research agency awarded Tudor Oprea, MD, PhD, a 2-year $4.9 million grant to develop a tool scientists can use to link information about drugs, diseases and genes. [More]
New study sheds light on relationship between schizophrenia and smoking stems

New study sheds light on relationship between schizophrenia and smoking stems

Schizophrenia is associated with increased rates and intensity of tobacco smoking. A growing body of research suggests that the relationship between schizophrenia and smoking stems, in part, from an effort by patients to use nicotine to self-medicate symptoms and cognitive impairment associated with the disease. [More]
Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University. [More]
Reproductive cell division has mechanical safeguard against chromosome sorting errors

Reproductive cell division has mechanical safeguard against chromosome sorting errors

Reproductive cell division has evolved a simple, mechanical solution to avoid chromosome sorting errors, researchers report in the Sept. 11 Science Express. [More]
Zebrafish may hold key to unlocking a leading cause of respiratory diseases

Zebrafish may hold key to unlocking a leading cause of respiratory diseases

A small freshwater fish found in many tropical aquariums may hold the key to unlocking one of the leading causes of respiratory diseases in humans. [More]
New method helps reveal secret dance of proteins

New method helps reveal secret dance of proteins

Staying clear of diseases requires that the proteins in our cells cooperate with one another. But, it has been a well-guarded secret how tens of thousands of different proteins find the correct dancing partners as they degrade and build up the human body, brain and nervous system. [More]
Novel genetic discovery identifies new avenues for prostate cancer treatment

Novel genetic discovery identifies new avenues for prostate cancer treatment

A genetic discovery out of the University of Pittsburgh School of Medicine is leading to a highly accurate test for aggressive prostate cancer and identifies new avenues for treatment. [More]
Research findings could help explain how some people stave off dementia

Research findings could help explain how some people stave off dementia

The human brain is capable of a neural workaround that compensates for the buildup of beta-amyloid, a destructive protein associated with Alzheimer's disease, according to a new study led by researchers at the University of California, Berkeley. [More]
Global study identifies another 23 new prostate cancer risk loci

Global study identifies another 23 new prostate cancer risk loci

Scientists could soon better predict a man's risk of getting prostate cancer after a worldwide team of researchers carried out the largest-ever analysis of the cancer's genetic biomarkers, reported in Nature Genetics today. [More]
Scientists develop new method to get clearer picture of how drug abuse affects the brain

Scientists develop new method to get clearer picture of how drug abuse affects the brain

One thing leads to another, especially in research. When Stony Brook University School of Medicine scientists developed a new method to measure how cocaine disrupts blood flow in the brains of mice, doctors and researchers got a way to form a clearer picture of how drug abuse affects the brain. [More]