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New stem-cell discovery may lead to more streamlined process for tissue regeneration

New stem-cell discovery may lead to more streamlined process for tissue regeneration

A new stem-cell discovery might one day lead to a more streamlined process for obtaining stem cells, which in turn could be used in the development of replacement tissue for failing body parts, according to UC San Francisco scientists who reported the findings in the current edition of Cell. [More]
Computational biologists develop program for diagnosing hereditary illnesses easily

Computational biologists develop program for diagnosing hereditary illnesses easily

In the case of a cough or a sore throat, the doctor can usually diagnose a common cold immediately. However, the diagnosis of hereditary illnesses like cystic fibrosis, which affects the metabolism, or Huntington's disease, which leads to cognitive decline, is much more complex. [More]
Researchers find molecule that irreversibly interferes with activity of mutated cancer gene

Researchers find molecule that irreversibly interferes with activity of mutated cancer gene

UT Southwestern Medical Center cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors. [More]
Researchers confirm for the first time that achalasia is autoimmune in origin

Researchers confirm for the first time that achalasia is autoimmune in origin

Achalasia is a rare disease - it affects 1 in 100,000 people - characterized by a loss of nerve cells in the esophageal wall. [More]
Biochemists report advance in production of functional mirror-image proteins

Biochemists report advance in production of functional mirror-image proteins

University of Utah biochemists have reported an advance in the production of functional mirror-image proteins. [More]
Researcher examines how motivated older adults maintain focus on cognitive tasks

Researcher examines how motivated older adults maintain focus on cognitive tasks

A psychology researcher at North Carolina State University is proposing a new theory to explain why older adults show declining cognitive ability with age, but don't necessarily show declines in the workplace or daily life. [More]
Little-known supportive cells in brain may play major role in cognitive function

Little-known supportive cells in brain may play major role in cognitive function

When you're expecting something-like the meal you've ordered at a restaurant-or when something captures your interest, unique electrical rhythms sweep through your brain. [More]
Researchers examine role of dairy products in preserving bone and skeletal muscle

Researchers examine role of dairy products in preserving bone and skeletal muscle

Understanding that diets are often built around food groups rather than specific nutrients, researchers from Switzerland, France, and North America decided to examine interactions between four nutrients found in dairy products and their role in preserving bone and skeletal muscle. [More]
Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

Researchers one step closer to finding treatment for Alzheimer's, other forms of dementia

There is no cure for Alzheimer's disease and other forms of dementia, but the research community is one step closer to finding treatment. [More]
Cancer researchers find molecule that irreversibly interferes with KRAS gene

Cancer researchers find molecule that irreversibly interferes with KRAS gene

UT Southwestern Medical Center cancer researchers have found a molecule that selectively and irreversibly interferes with the activity of a mutated cancer gene common in 30 percent of tumors. [More]
Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Research conducted at the Florida campus of The Scripps Research Institute has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer's underlying genetic causes. [More]
PLXNA4 gene may increase risk of developing Alzheimer's disease

PLXNA4 gene may increase risk of developing Alzheimer's disease

Researchers from Boston University School of Medicine report variants in a new gene, PLXNA4, which may increase the risk of developing Alzheimer's disease (AD). The discovery of this novel genetic association may lead to new drug treatment options that target PLXNA4 specifically. [More]
Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

Nicotine, cotinine can potentially inhibit DNA damage caused by NNK in tobacco smoke

A new in vitro study has revealed that nicotine and cotinine, a metabolite of nicotine, can potentially inhibit DNA damage caused by a certain carcinogen in smoke. [More]
Antifungal drug resistance evoked through RNAi-dependent epimutations

Antifungal drug resistance evoked through RNAi-dependent epimutations

Microorganisms like bacteria and fungi can evade treatment by acquiring mutations in the genes targeted by antibiotics or antifungal drugs. [More]
Parallel brain circuits associated with opposing emotional reactions

Parallel brain circuits associated with opposing emotional reactions

People choosing between two or more equally positive outcomes experience paradoxical feelings of pleasure and anxiety, feelings associated with activity in different regions of the brain, according to research led by Amitai Shenhav, an associate research scholar at the Princeton Neuroscience Institute at Princeton University. [More]
Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Melatonin has protective effects on traumatic brain injury-induced cerebral cortex

Traumatic brain injury can cause post-traumatic neurodegenerations with an increase in reactive oxygen species and reactive oxygen species-mediated lipid peroxidation. Melatonin, a non-enzymatic antioxidant and neuroprotective agent, has been shown to counteract oxidative stress-induced pathophysiologic conditions like cerebral ischemia/reperfusion injury, neuronal excitotoxicity and chronic inflammation. [More]
Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Study provides potential drug targets for transient cerebral ischemia-reperfusion injury

Mitochondria play an important role in neuronal apoptosis caused by cerebral ischemia. Researchers at the Affiliated Hospital of Qingdao University, China discovered transient ischemia led to cell apoptosis in the hippocampus and changes in memory and cognition of aged rats. [More]
Neuroscientists shed new light on how the brain works

Neuroscientists shed new light on how the brain works

Neuroscientists in Bonn and Heidelberg have succeeded in providing new insights into how the brain works. Researchers at the DZNE and the German Cancer Research Center analyzed tissue samples from mice to identify how two specific proteins, ‘CKAMP44’ and ‘TARP Gamma-8’, act upon the brain’s memory center. [More]
Xbp1s protein plays key role in brain regions to regulate metabolism

Xbp1s protein plays key role in brain regions to regulate metabolism

A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found. [More]
Trials show immunizations are effective in adults

Trials show immunizations are effective in adults

As kids prepare to head back to school, required immunizations are typically on the to-do list, but getting potentially lifesaving vaccines should not end when adulthood begins, says one University of Alabama at Birmingham infectious diseases expert. [More]