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Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Brains of people with autism share similar pattern of abnormal gene activity, UCLA study shows

Autism spectrum disorder is caused by a variety of factors, both genetic and environmental. [More]
UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass researchers develop new class of photodynamic molecules for treating deep-tissue tumors

UMass Medical School scientist Gang Han, PhD, and his team have designed a new class of molecules used in photodynamic therapy that are able to direct lamp light deep into tissue to kill cancer tumors. [More]
Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

Scientists identify potential dual-acting therapeutic strategy for aggressive form of breast cancer

A promising new combination therapy for a particularly aggressive form of breast cancer has been identified by Weizmann Institute scientists, as was recently reported in Cancer Research. [More]
Gut microbes may play important role in exacerbated post-dieting weight gain

Gut microbes may play important role in exacerbated post-dieting weight gain

Following a successful diet, many people are dismayed to find their weight rebounding - an all-too-common phenomenon termed "recurrent" or "yo-yo" obesity. [More]
Starvation may shorten lifespans of children and male descendants, study suggests

Starvation may shorten lifespans of children and male descendants, study suggests

New Tel Aviv University research suggests that periods of fasting or starvation may significantly shorten the lifespans of both children and their male descendants. [More]
Baby's first words most likely to depend upon visual experience, IU research finds

Baby's first words most likely to depend upon visual experience, IU research finds

Indiana University psychologists have shown that a baby's most likely first words are based upon their visual experience, laying the foundation for a new theory of infant language learning. [More]
MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

MUSC researchers harness cutting-edge technology to uncover new role for pericytes during stroke

Pericytes are the primary locus of matrix-mellaproteinase-9-dependent (MMP-9) capillary damage and blood leakage during ischemia, according to preclinical findings reported by Medical University of South Carolina investigators in an article published online on November 14, 2016 by The Journal of Neuroscience. [More]
UC Riverside scientists identify mechanism that creates immunity to influenza A virus

UC Riverside scientists identify mechanism that creates immunity to influenza A virus

A team of researchers, co-led by a University of California, Riverside professor, has found a long-sought-after mechanism in human cells that creates immunity to influenza A virus, which causes annual seasonal epidemics and occasional pandemics. [More]
BUSM researchers discover role of hippocampus in future thinking

BUSM researchers discover role of hippocampus in future thinking

Over the past decade, researchers have learned that the hippocampus--historically known for its role in forming memories--is involved in much more than just remembering the past; it plays an important role in imagining events in the future. [More]
Research unlocks potential new therapies for inflammatory diseases

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue. [More]
Milk from genetically-altered goats may trigger less severe allergic reactions, study finds

Milk from genetically-altered goats may trigger less severe allergic reactions, study finds

The presence of the allergen β-Lactoglobulin (BLG) in the milk of goats and other ungulates restricts the consumption of goat's milk by humans. [More]
New drug treatment can override genetic fault that causes choroideremia

New drug treatment can override genetic fault that causes choroideremia

Researchers with funding from Fight for Sight have demonstrated that a new drug treatment for cystic fibrosis and Duchenne muscular dystrophy can override a genetic fault that causes choroideremia – a severe blinding disorder. [More]
Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Combination treatment produces better outcomes in erythropoietin-refractory MDS patients, study shows

Patients with myelodysplastic syndromes (MDS) suffer from a reduction in the number of different types of blood cells, including red blood cells leading to the development of anemia. [More]
Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Researchers develop portable sensor for fast, accurate assessment of blood's clotting ability

Case Western Reserve University researchers have developed a portable sensor that can assess the clotting ability of a person's blood 95 times faster than current methods—using only a single drop of blood. [More]
Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Hemophilia B patients produce near-normal levels of clotting factor IX after gene therapy, study shows

Researchers are reporting the highest and most sustained levels to date of the essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B. [More]
Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Clonal hematopoiesis may help predict cancer patients at risk for fatal form of leukemia

Patients successfully treated for breast, colon and other cancers can go on to develop an often-fatal form of leukemia, sometimes years after completion of treatment, due to a genetic mutation leading to secondary malignancies known as therapy-related myeloid neoplasms (t-MNs). [More]
Researchers assess scientific rigor in animal experimentation

Researchers assess scientific rigor in animal experimentation

The "reproducibility crisis" in biomedical research has led to questions about the scientific rigor in animal research, and thus the ethical justification of animal experiments. [More]
Study reveals new way to improve stability of common protein drugs

Study reveals new way to improve stability of common protein drugs

Gaining access to important biopharmaceuticals needed to treat illnesses and autoimmune diseases is one of the biggest obstacles developing countries face. [More]
Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Genetic differences between brain cancer cells and normal tissues could offer clues to tumor behavior

Two recently discovered genetic differences between brain cancer cells and normal tissue cells -- an altered gene and a snippet of noncoding genetic material -- could offer clues to tumor behavior and potential new targets for therapy, Johns Hopkins scientists report. [More]
Auditory deficits in people with schizophrenia linked to dysfunctional brain receptors

Auditory deficits in people with schizophrenia linked to dysfunctional brain receptors

The inability to hear subtle changes in pitch, a common and debilitating problem for people with schizophrenia, is due to dysfunctional N-methyl-D-aspartate (NMDA) brain receptors, according to a study by Columbia University Medical Center researchers. [More]
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