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New urine-based test improves identification of high-grade prostate cancer

Researchers at the University of Michigan Rogel Cancer Center have developed a new urine-based test that addresses a major problem in prostate cancer: how to separate the slow-growing form of the disease unlikely to cause harm from more aggressive cancer that needs immediate treatment.

18 Apr 2024

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting.

18 Apr 2024

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person's quality of life.

18 Apr 2024

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Researchers have discovered toxic protein particles, shaped like umbrellas, that soil bacteria known as Streptomyces secrete to squelch competitors, especially others of their own species.

17 Apr 2024

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

In an ambitious new study, a research team that included scientists from Yale set out to uncover potential treatments for patients with rare neuroendocrine tumors of the cervix (NETc) by understanding the molecular basis of the aggressive disease.

17 Apr 2024

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

17 Apr 2024

Study identifies genomic variant linked to unique human skull base morphology

Humans, Homo sapiens, have unique features compared with other closely related hominin species and primates, including the shape of the base of the skull.

17 Apr 2024

Vitamin D deficiency persists despite easy access, review suggests need for tailored supplements

Researchers in a study published in the journal Nutrients delve into the pervasive issue of vitamin D deficiency and its link to various health conditions, advocating for precision nutrition and personalized supplementation to enhance vitamin D intake and effectiveness.

17 Apr 2024

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Study reveals molecular changes in brain cells with Lewy bodies

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson's disease and some dementias.

16 Apr 2024

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Antisense oligonucleotides (ASOs) are next-generation drugs that can treat disease by blocking the transfer of harmful messages from our genes.

16 Apr 2024

Study reveals human gut plasmid with biomarker potential

A component of the human intestinal flora that has been little studied to date is the focus of a new study.

16 Apr 2024

Placental IGFBP1: A key factor in development of gestational diabetes

A new study led by the Harvard Pilgrim Health Care Institute has identified that a deficit in the placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low IGFBP1 circulating levels are associated with insulin resistance during pregnancy, highlighting a potential risk factor for the development of gestational diabetes.

16 Apr 2024

Pitt researchers uncover mechanisms behind uveal melanoma resistance

New research from the University of Pittsburgh explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy, which involves growing a patient's T cells outside the body before reinfusing them, can successfully treat this rare and aggressive cancer.

16 Apr 2024

Arabica coffee's genetic legacy unveiled

The key to growing coffee plants that can better resist climate change in the decades to come may lie in the ancient past.

15 Apr 2024

New class of AI tackles complex diseases by incorporating scientific knowledge

Mayo Clinic researchers recently invented a new class of artificial intelligence (AI) algorithms called hypothesis-driven AI that are a significant departure from traditional AI models which learn solely from data.

15 Apr 2024

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Bacterial infections pose significant challenges to agriculture and medicine, especially as cases of antibiotic-resistant bacteria continue to rise.

15 Apr 2024

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

A new study conducted by researchers at Tampere University and Tampere University Hospital revealed how aberrant epigenetic regulation contributes to the development of atypical teratoid/rhabdoid (AT/RT) tumors, which are aggressive brain tumors that mainly affect young children.

15 Apr 2024

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

How muscle changes with aging, and tries to fight its effects, is now better understood at the cellular and molecular level with the first comprehensive atlas of aging muscles in humans.

15 Apr 2024

Tiny DNA circles are key drivers of cancer formation, study suggests

Tiny circles of DNA that defy the accepted laws of genetics are key drivers of cancer formation, according to an international study led by researchers at Stanford Medicine.

15 Apr 2024

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Genes News and Research

New urine-based test improves identification of high-grade prostate cancer

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

Study pinpoints 95 locations in the genome associated with risk of developing PTSD

Novel antibacterial discovery: Umbrella toxin particles secreted by Streptomyces

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

Discovery of DNA repair mechanism advances understanding of how human cells stay healthy

Study identifies genomic variant linked to unique human skull base morphology

Vitamin D deficiency persists despite easy access, review suggests need for tailored supplements

Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Study reveals molecular changes in brain cells with Lewy bodies

Study reveals novel approach to promote efficient uptake of ASOs into cancer cells

Study reveals human gut plasmid with biomarker potential

Placental IGFBP1: A key factor in development of gestational diabetes

Pitt researchers uncover mechanisms behind uveal melanoma resistance

Arabica coffee's genetic legacy unveiled

New class of AI tackles complex diseases by incorporating scientific knowledge

Texas A&M scientists elucidate how phages disarm antibiotic-resistant bacteria

Study reveals how aberrant epigenetic regulation contributes to aggressive pediatric brain tumors

First comprehensive atlas sheds new light on processes underlying age-related muscle changes

Tiny DNA circles are key drivers of cancer formation, study suggests

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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