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Novel mechanism enhances the formation of hematopoietic stem cells

Hematopoietic stem cells can replenish all the different cell types of our blood system. For this reason, hematopoietic stem cells are the cells used in many blood diseases when patients need transplantations.

17 Nov 2020

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Managing the activity of the BCAP protein could help the body repair intestinal tissue from damage caused by inflammation, according to a new study led by experts at Cincinnati Children's.

17 Nov 2020

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

The Department for Health and Social Care Testing Innovation Fund has backed the Wellcome Sanger Institute and the COVID-19 Genomics UK Consortium in expanding whole genome sequencing of positive SARS-CoV-2 virus samples to map how COVID-19 spreads and evolves.

16 Nov 2020

COVID-19 outbreak on an American aircraft carrier: A case study in transmission

A new study showing the dynamics of infectious spread within close quarters of an aircraft carrier. The study presents a rich case study that may help us better understand the dynamics of SARS-CoV-2’s transmission and thereby fine-tune present policies that aim to prevent its spread.

16 Nov 2020

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Itraconazole is a broad-spectrum antifungal agent that has been shown to have some in vitro activity against SARS-CoV-2 by a team of Belgian and German researchers.

16 Nov 2020

Metabolic biomarkers could predict COVID-19 severity

A new study suggests that metabolic biomarkers could possibly predict the severity of COVID-19 in patients.

16 Nov 2020

Care pathways for pregnant women with COVID‐19

A recent review published in the journal Global Challenges in October 2020, sums up what is currently known about the treatment of COVID-19 during pregnancy and offers recommendations for how healthcare professions might better manage pregnant COVID-19 patients in the future.

16 Nov 2020

Xylitol and grapefruit seed extract nasal spray could help COVID-19 patients

United States based researchers have published a report exploring the potential role of Xylitol and Grapefruit seed extract (in the form of a nasal spray) in treating COVID-19.

16 Nov 2020

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

A new paper published in the journal Science of the Total Environment on November 10, 2020, discusses the reality of the virus’s wastewater transmission. Overall, the researchers found that wastewater transmission would have a disproportionate impact on countries with low development indices.

15 Nov 2020

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

Scientists in Taiwan recently published a report on their use of anti-neutrophil strategies to treat acute respiratory distress syndrome (ARDS) – a life-threatening condition that can arise in critical COVID-19 cases – in the journal Frontiers in Pediatrics.

15 Nov 2020

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

A new saliva-based test developed by a team at Johns Hopkins Bloomberg School of Public Health has been found to accurately detect the presence of antibodies to SARS-CoV-2, the virus that causes COVID-19, from small samples of saliva, according to a study led by Bloomberg School researchers.

15 Nov 2020

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

A recent study published in the International Journal of Infectious Diseases has explained the lower prevalence of coronavirus disease 2019 (COVID-19) in sub-Saharan Africa compared to that in the US, Europe, and Asia.

15 Nov 2020

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

With the coronavirus disease 2019 (COVID-19) pandemic infecting over 52.7 million people around the world, and killing over 1.2 million, a large amount of research has tried to better understand immune responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes COVID-19.

15 Nov 2020

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

A research team from the Engelhardt Institute of Molecular Biology in Russia have shown that Nsp1 – a non-structured protein present in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen – stimulates translation termination in the stop codon recognition stage. Studying and developing drugs that compete with Nsp1 for binding with the termination complex could therefore be a potential strategy for fighting against coronavirus disease 2019 (COVID-19).

15 Nov 2020

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

A recent study published in the journal Child Abuse and Neglect has reported that the number of child maltreatment reports and child welfare interventions decreased significantly in New York City during the initial phase of the coronavirus disease 2019 (COVID-19) pandemic.

12 Nov 2020

Hantavirus can also be transmitted by wild or domesticated rats

A group of researchers from Charité - Universitätsmedizin Berlin have confirmed Germany's first-ever case of animal-to-human transmission involving a specific species of virus known as the 'Seoul virus'.

12 Nov 2020

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

A new study published on the preprint server bioRxiv in November 2020 describes the virus's N protein as a promising epitope for serology.

12 Nov 2020

SARS-CoV-2-induces temporary loss of smell in mice

Now, a new study published on the preprint server bioRxiv in November 2020 presents the onset of olfactory dysfunction (loss of smell) in mice infected with the virus, examining this process at the cellular level. In doing so, this study throws more light on this curious symptom and COVID-19’s manifestations outside the lungs.

12 Nov 2020

Convalescent plasma in COVID-19 can be effective, especially early in disease

A team of researchers in the United States have conducted an extensive literature review looking at the usage of convalescent plasma from recovered COVID-19 patients to treat those with an impaired immune system. Their study, titled “Therapeutic use of convalescent plasma in COVID-19 patients with immunodeficiency: A systematic review,” has been released on medRxiv*, the preprint server.

12 Nov 2020

Common spike mutation may make SARS-CoV-2 more susceptible to a vaccine

A new study published in Science confirms that SARS-CoV-2 has mutated in a way that's enabled it to spread quickly around the world, but the spike mutation may also make the virus more susceptible to a vaccine.

12 Nov 2020

Pathogen News and Research

Novel mechanism enhances the formation of hematopoietic stem cells

Targeting BCAP with new drugs could benefit people with inflammatory bowel disease

Sanger Institute and COG-UK get £12.2M funding to build genomic surveillance system for COVID-19

COVID-19 outbreak on an American aircraft carrier: A case study in transmission

Antifungal agent Itraconazole inhibits SARS CoV-2 in vitro

Metabolic biomarkers could predict COVID-19 severity

Care pathways for pregnant women with COVID‐19

Xylitol and grapefruit seed extract nasal spray could help COVID-19 patients

Measures to prevent SARS-CoV-2 transmission through wastewater in poor regions

Drugs targeting neutrophils could reduce ARDS in severe COVID-19

New saliva-based test found to accurately detect the presence of SARS-CoV-2 antibodies

High prevalence of cross-reactive anti-SARS-CoV-2 antibodies in sub-Saharan Africa

SARS-CoV-2 immunity may last over six months through antibody evolution and B cell memory

Antimalarials could disrupt SARS-CoV-2’s Nsp1 translation termination

250,000 cases of child abuse or neglect may have gone unreported in U.S. COVID pandemic

Hantavirus can also be transmitted by wild or domesticated rats

Promising SARS-CoV-2 N epitope for more accurate diagnostic and surveillance antibody testing

SARS-CoV-2-induces temporary loss of smell in mice

Convalescent plasma in COVID-19 can be effective, especially early in disease

Common spike mutation may make SARS-CoV-2 more susceptible to a vaccine

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