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Study reveals causes of community-acquired pneumonia in children

Study reveals causes of community-acquired pneumonia in children

With the chill of winter comes a spike in community-acquired pneumonia (CAP), which spreads more easily as people retreat indoors and come into close contact. The lung infection triggers persistent coughing, chest pain, fever, and difficulty breathing, and is particularly hard on the very young and the very old. In fact, pneumonia is the leading cause of hospitalization among U.S. children, with estimated medical costs of $1 billion annually. [More]
MRIGlobal awarded contract to develop Sample-to-Sequence system for diagnosis of infectious diseases

MRIGlobal awarded contract to develop Sample-to-Sequence system for diagnosis of infectious diseases

MRIGlobal today announced that it has been awarded a $14.8 million contract to develop an end-to-end next generation sequencing system for clinical diagnosis of infectious diseases. [More]
Researchers explore influence of host organisms on bacterial metabolism

Researchers explore influence of host organisms on bacterial metabolism

Monika Ehling-Schulz's group from the Institute of Microbiology, together with Mathias Müller's group at the Institute of Animal Breeding and Genetics studied the influence of host organisms on bacterial metabolism. The researchers infected three different lineages of mice with the bacteria Listeria monocytogenes. The mouse strains showed significant differences in their response to the infection and in the severity of the clinical symptoms. [More]
Ready to reconstitute BPW adds convenient option to support high throughput Salmonella testing in chocolate production

Ready to reconstitute BPW adds convenient option to support high throughput Salmonella testing in chocolate production

The discovery of Salmonella in one batch of a particular chocolate product, which prompted a recent recall, is a reminder of the importance of this pathogen in confectionery products. [More]
IDRI Announces $4M BARDA Cooperative Agreement To Establish Adjuvant Hub

IDRI Announces $4M BARDA Cooperative Agreement To Establish Adjuvant Hub

The international outbreak of Ebola in 2014 serves as a reminder for the need to be proactive in preparing for the rapid spread of any newly emerging or re-emerging infectious disease. IDRI today announces it has received $4 million in funding from the Biomedical Advanced Research and Development Authority, part of the U.S. Department of Health and Human Services, to develop an adjuvant manufacturing hub with both preclinical and clinical expertise to facilitate pandemic influenza preparedness in developing countries. [More]
Weill Cornell receives NIH grant to study TB-causing bacteria

Weill Cornell receives NIH grant to study TB-causing bacteria

In an effort to stop tuberculosis (TB) from becoming progressively less treatable worldwide, the National Institutes of Health has awarded Weill Cornell Medical College more than $6.2 million in first-year funding to support a research collaboration among six institutions in close alliance with voluntary pharmaceutical partners. [More]
Researchers report first evidence of Seoul hantavirus in wild rats in the Netherlands

Researchers report first evidence of Seoul hantavirus in wild rats in the Netherlands

In a paper just published in the peer reviewed journal Infection, Ecology & Epidemiology, researchers report discovering the first evidence of Seoul hantavirus (SEOV) in the wild rat population in the Netherlands. The discovery comes on the heels of similar ones in France, Belgium and the United Kingdom in recent years, and has some researchers concerned about the potential spread of the virus to humans. [More]
Climate change causes emergence of more infectious diseases

Climate change causes emergence of more infectious diseases

The appearance of infectious diseases in new places and new hosts, such as West Nile virus and Ebola, is a predictable result of climate change, says a noted zoologist affiliated with the Harold W. Manter Laboratory of Parasitology at the University of Nebraska-Lincoln. [More]
New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

New antibody shows promise in increasing survival for patients suffering from influenza, pneumonia

Scientists from NTU Singapore, the world's No. 1 young university, have developed an antibody which boosts the survival chances for patients suffering from influenza and pneumonia. [More]
Great Basin Scientific begins clinical trial for Shiga toxin-producing E. coli diagnostic test

Great Basin Scientific begins clinical trial for Shiga toxin-producing E. coli diagnostic test

Great Basin Scientific, Inc., today announced it has initiated a clinical trial for its Shiga toxin-producing E. coli (STEC) diagnostic test. [More]
SIB Swiss Institute of Bioinformatics designated as FAO Reference Centre for bioinformatics

SIB Swiss Institute of Bioinformatics designated as FAO Reference Centre for bioinformatics

The Food and Agriculture Organization of the United Nations (FAO) has appointed SIB Swiss Institute of Bioinformatics as the FAO Reference Centre for bioinformatics. [More]
Oral pathogen protects different tumor cells from being killed by immune cells

Oral pathogen protects different tumor cells from being killed by immune cells

Bacteria that are commonly found in the mouth are often abundant in patients with colon cancer, but the potential role these microbes play in tumor development has not been clear. A study published by Cell Press February 18th in the journal Immunity reveals that the oral pathogen Fusobacterium nucleatum protects a variety of tumor cells from being killed by immune cells. [More]
Standard cleaning procedures in retail delis may not eradicate Listeria pathogen, study shows

Standard cleaning procedures in retail delis may not eradicate Listeria pathogen, study shows

Purdue University research shows that standard cleaning procedures in retail delis may not eradicate Listeria monocytogenes bacteria, which can cause a potentially fatal disease in people with vulnerable immune systems. [More]
Experimental Ebola virus medication shows promise in monkeys

Experimental Ebola virus medication shows promise in monkeys

An experimental medication that targets a protein in Ebola virus called VP24 protected 75% of a group of monkeys that were studied from Ebola virus infection, according to new research conducted by the U.S. Army, in collaboration with Sarepta Therapeutics, Inc. [More]
Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics reports positive results from SYN-004 Phase 1b trial to prevent C. difficile infection

Synthetic Biologics, Inc., a developer of pathogen-specific therapies for serious infections and diseases, with a focus on protecting the microbiome, today announced positive topline safety and tolerability results from a Phase 1b clinical trial of SYN-004, the Company's investigational oral beta-lactamase enzyme designed to protect the microbiome and prevent Clostridium difficile (C. difficile) infection, antibiotic-associated diarrhea and secondary antibiotic-resistant infections in patients receiving intravenous (IV) beta-lactam antibiotic therapy. [More]
University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

University of Tokyo researchers reveal how TLR9 binds to pathogen DNA

University of Tokyo researchers have elucidated how Toll-like receptor 9 (TLR9) binds to pathogen DNA, activating the innate immune system. This discovery is vital for the design of new antiviral, antibacterial, allergy and other drugs targeting TLR9. [More]
IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

IU researchers awarded NIH grant to develop new weapon to fight against antibiotic-resistant bacteria

The alarming increase of antibiotic-resistant bacteria poses health and economic threats worldwide, with more than 2 million Americans infected by the bacteria each year. Now, a team of Indiana University chemists and biologists has been awarded a major grant to develop and use a chemical tagging method to better understand how bacteria build their cell wall, which is still the best target for new antibiotics. [More]
Scientists sequence genetic code of roundworm that causes disease in humans, animals

Scientists sequence genetic code of roundworm that causes disease in humans, animals

For the first time, scientists have sequenced the genetic code of Toxocara canis, a roundworm that causes disease in humans and animals, which paves the way for new drugs, vaccines and diagnostic tests. [More]
Researchers document pathological progress of multiple sclerosis

Researchers document pathological progress of multiple sclerosis

The Centre for Brain Research at the MedUni Vienna is regarded as a world leader in researching the mechanisms involved with multiple sclerosis (MS). Now, in a paper published in the highly respected journal Lancet Neurology, an international team of researchers from Edinburgh, Cleveland and Vienna, under the leadership of Hans Lassmann, Head of the Department of Neuroimmunology at the MedUni Vienna, has for the first time documented the pathological progress of the disease from its early to late stage and also shown that inflammatory and neurodegenerative processes have a role to play. [More]
Investigators develop microbiome map of New York City subway system

Investigators develop microbiome map of New York City subway system

The microbes that call the New York City subway system home are mostly harmless, but include samples of disease-causing bacteria that are resistant to drugs -- and even DNA fragments associated with anthrax and Bubonic plague -- according to a citywide microbiome map published today by Weill Cornell Medical College investigators. [More]