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Discovering a new role for a protein that could cause breast cancer to spread to the lungs

In this interview, News-Medical speaks to Dr. Cristina Branco from Breast Cancer Now about the spread of breast cancer cells to the lungs.

12 Nov 2020

Disinfectants with "virucidal activity against enveloped viruses" effective against SARS-CoV-2

A recent study demonstrated that two commercially available surface disinfectant formulations and one hand disinfection formulation that claim "virucidal activity against enveloped viruses" are effective in inactivating the SARS-CoV-2 virus. Their study has been published on the preprint server bioRxiv.

11 Nov 2020

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

A new study in the preprint server bioRxiv published in November 2020 describes the discovery of acrylamide fragments that can effectively disable key enzymes in both the hand, foot and mouth virus and SARS-CoV-2 virus.

11 Nov 2020

Human coronaviruses cause processing body loss

Researchers continue to expand their knowledge of coronaviruses, including the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen. Now, a new study published on the preprint server bioRxiv in November 2020 describes a vital mechanism whereby the novel SARS-CoV-2 pathogen can restrict the human host response. In doing so, the study explores how this novel feature of SARS-CoV-2 works and how it results in a reshaping of the human host's immune response.

11 Nov 2020

Nafamostat mesylate initially reduces SARS-CoV-2 viral loads in hamsters, study finds

Researchers have found that nafamostat mesylate, when injected in the nasal cavity of Syrian hamsters, can decrease initial SARS-CoV-2 viral loads in their nose. However, this effect was temporary and further testing is required to determine clinically significant effects. The research group's findings are available on the preprint server bioRxiv*.

11 Nov 2020

Researchers use machine learning algorithm to identify common respiratory pathogens

The ongoing global pandemic has created an urgent need for rapid tests that can diagnose the presence of the SARS-CoV-2 virus, the pathogen that causes COVID-19, and distinguish it from other respiratory viruses.

11 Nov 2020

How SARS-CoV-2 blocks immune response

An international research team has confirmed the mechanism by which the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Their article titled, “SARS-CoV-2 Orf6 hijacks Nup98 to block STAT nuclear import and antagonize interferon signaling,” is published in the journal Proceedings of the National Academy of Sciences.

11 Nov 2020

Lessons from USS Theodore Roosevelt on limiting shipborne COVID-19 outbreaks

A new study published on the preprint server medRxiv* in November 2020 discusses such a scenario in terms of various possible approaches. It suggests that a viable strategy could be evacuating everyone from the ship and extensive surveillance testing.

10 Nov 2020

Endothelial cells resistant to SARS-CoV-2 infection

A team of scientists from Imperial College London has conducted a series of in vitro studies to investigate the susceptibility of endothelial cells to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, the causative pathogen of coronavirus disease 2019 (COVID-19).

10 Nov 2020

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

Over the next six years, research groups at Charité - Universitätsmedizin Berlin and Tel Aviv University will study how invasive fungal pathogens are able to evade treatments and develop tolerance to antifungal drugs.

10 Nov 2020

NAU researcher leads international effort to study and track brucellosis

Northern Arizona University researcher Jeff Foster is leading an international effort to study and track the spread of one of the most important infectious diseases in humans and livestock worldwide.

10 Nov 2020

Using wastewater epidemiology to monitor SARS-CoV-2 in Houston

Now, a team of researchers at Rice University, Baylor College of Medicine, and the Houston Health Department show SARS-CoV-2 RNA wastewater levels to be a strong predictive of trends in the nasal positivity rate two weeks in advance. This could help track the positivity rate for populations, speeding up the isolation and treatment of infected people.

9 Nov 2020

Effective surveillance of non-symptomatic hosts key to preventing local outbreaks during epidemics

A team of researchers in the UK and Israel have warned that during infectious disease epidemics such as coronavirus disease 2019 (COVID-19), effective surveillance of non-symptomatic hosts is essential to preventing local outbreaks.

9 Nov 2020

Translational study within SARS-CoV-2 infected cells opens up new therapeutic avenues

A recent study published on the preprint server bioRxiv in October 2020 shows what the protein translation process looks like in specific terms. In doing so, the study has provided new insights that might prove helpful in developing new therapies for COVID-19 patients.

9 Nov 2020

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

An international team of researchers has shown that a mutation within severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent responsible for the coronavirus disease 2019 (COVID-19) – enables the pathogen to evade antibody-mediated immunity while maintaining replication fitness and increasing viral loads.

9 Nov 2020

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

A team of researchers at the Biomedical Primate Research Centre based in the Netherlands have aimed to determine the effects of the SARS-CoV-2 pathogen on these monkeys and, subsequently, whether they make good animal models for future research in the area.

8 Nov 2020

Decreasing humidity in the winter is likely to lead to more COVID-19 cases

A team of researchers from the Center for Disease Dynamics, Economics & Policy, USA, and Johns Hopkins University, USA, found evidence to support the notion that increased humidity may have contributed to lesser cases in spring earlier this year (2020). However, as the winter season fast approaches, the researchers fear that the decreasing humidity is likely to lead to an increase in COVID-19 cases.

8 Nov 2020

Innate immunity key to limiting viral load in COVID-19 cases

As the coronavirus disease 2019 (COVID-19) pandemic continues to cause many difficulties for public health authorities, research is ongoing to understand how the virus can cause fatal effects on those infected and thereby suggest effective preventive and therapeutic measures against it.

8 Nov 2020

Second wave of COVID-19 in UK has reached “critical” stage, says study

The current paper reports the preliminary findings of the sixth round of the REal-time Assessment of Community Transmission-1 (REACT-1) study, which has traced the path of the outbreak in England since May this year (2020).

8 Nov 2020

Study opens a new avenue for prophylactic anti-malarial strategies

A new study led by Maria Manuel Mota, group leader at Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal), now shows that malaria parasites secrete the protein EXP2 that is required for their entry into hepatocytes.

6 Nov 2020

Pathogen News and Research

Discovering a new role for a protein that could cause breast cancer to spread to the lungs

Disinfectants with "virucidal activity against enveloped viruses" effective against SARS-CoV-2

Researchers identify acrylamides that inhibit SARS-CoV-2 main protease

Human coronaviruses cause processing body loss

Nafamostat mesylate initially reduces SARS-CoV-2 viral loads in hamsters, study finds

Researchers use machine learning algorithm to identify common respiratory pathogens

How SARS-CoV-2 blocks immune response

Lessons from USS Theodore Roosevelt on limiting shipborne COVID-19 outbreaks

Endothelial cells resistant to SARS-CoV-2 infection

ERC Synergy project explores causes of drug tolerance in intractable fungal infections

NAU researcher leads international effort to study and track brucellosis

Using wastewater epidemiology to monitor SARS-CoV-2 in Houston

Effective surveillance of non-symptomatic hosts key to preventing local outbreaks during epidemics

Translational study within SARS-CoV-2 infected cells opens up new therapeutic avenues

Immune-evading variants can emerge in SARS-CoV-2, researchers warn

Researchers compare rhesus and cynomolgus macaques for SARS-CoV-2 vaccine trials

Decreasing humidity in the winter is likely to lead to more COVID-19 cases

Innate immunity key to limiting viral load in COVID-19 cases

Second wave of COVID-19 in UK has reached “critical” stage, says study

Study opens a new avenue for prophylactic anti-malarial strategies

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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