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Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Stem cells are different from all other cells in our body because they retain the remarkable genetic plasticity to self-renew indefinitely as well as develop into cell types with more specialized functions. However, this remarkable self-renewal capacity comes with a price, as stem cells can become seeds of cancer.

15 Apr 2013

Chronic daily pain continues to be burden for limb-injured veterans, says pain management expert

Veterans who sustained major limb injuries during combat reported little improvement in symptoms of depression, anxiety, post-traumatic stress disorder and other mental-health problems up to 2 years post injury, according to research presented today.

15 Apr 2013

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division.

15 Apr 2013

Matrix-Bio, Quest Diagnostics enter global licensing agreement for metabolomic biomarkers

Matrix-Bio, Inc., a diagnostics company that uses metabolite profiling to detect cancer and other diseases, has signed an exclusive global licensing and marketing agreement for metabolomic biomarkers with Quest Diagnostics, the world's leading provider of diagnostic information services. Under the agreement, Quest Diagnostics will have the rights to use the biomarkers for the future, potential development of a clinical lab-developed test to aid in the detection of breast cancer recurrence.

From Quest Diagnostics 12 Apr 2013

Study reveals inner workings of master regulator that controls diverse functions

New discoveries by a team of scientists at LSU Health Sciences Center New Orleans for the first time reveal the inner workings of a master regulator that controls functions as diverse as the ability of nerve cells to "rewire" themselves in response to external stimuli and the mechanism by which certain viruses hijack normal cellular processes to facilitate their replication that can ultimately lead to cancer. The research will be published in the April 12, 2013 issue of the Journal of Biological Chemistry.

12 Apr 2013

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Researchers have been able to reconstruct the genome sequence of an outbreak strain of Shiga-toxigenic Escherichia coli (STEC), which caused over 50 deaths in Germany, using an approach known as metagenomics which bypasses the need for growing bacteria in the lab.

12 Apr 2013

Researchers identify new potential therapeutic target for lowering cholesterol

Researchers at the University of Michigan have identified a new potential therapeutic target for lowering cholesterol that could be an alternative or complementary therapy to statins.

12 Apr 2013

Study sheds light on role of microglia during progression of Alzheimer's disease

The plaque deposits in the brain of Alzheimer's patients are surrounded by the brain's own immune cells, the microglia. This was already recognized by Alois Alzheimer more than one hundred years ago. But until today it still remains unclear what role microglia play in Alzheimer's disease.

12 Apr 2013

Sanofi launches large-scale production of artemisinin for malaria

Twelve years after a breakthrough discovery in his University of California, Berkeley, laboratory, professor of chemical engineering Jay Keasling is seeing his dream come true.

12 Apr 2013

Salk neuroscientists propose how visual system automatically adapts to new environments

The irony of getting away to a remote place is you usually have to fight traffic to get there. After hours of dodging dangerous drivers, you finally arrive at that quiet mountain retreat, stare at the gentle waters of a pristine lake, and congratulate your tired self on having "turned off your brain."

12 Apr 2013

Australian, Singapore researchers join hands to combat disease-causing bugs

The fight against a number of significant infectious diseases in the Asia-Pacific region has been given a boost through a new research collaboration between the National Health and Medical Research Council in Australia and the Agency for Science, Technology and Research in Singapore.

12 Apr 2013

New research shows safety can be improved for people participating in medical experiments

In almost 90 per cent of cases, novel drugs tested on humans by pharmaceutical companies do not work as intended and must be scrapped. Often the drugs do not work, while at worst, test subjects die. New research from the University of Southern Denmark now shows that this number can be reduced.

12 Apr 2013

Newly characterized adenoviruses can cause severe human infections

The ongoing dance between a virus and its host distinctly shapes how the virus evolves. While human adenoviruses typically cause mild infections, recent reports have described newly characterized adenoviruses that can cause severe, sometime fatal, human infections.

12 Apr 2013

Researchers identify defective gene responsible for isolated congenital asplenia

The spleen is rarely noticed, until it is missing. In children born without this organ, that doesn't happen until they become sick with life-threatening bacterial infections.

12 Apr 2013

Research on soy-based treatment for colorectal cancer presented at AACR annual meeting

Research on a soy-based treatment for colorectal cancer, a promising agent in ovarian cancer, and a new drug target for advanced prostate cancer was presented at the American Association for Cancer Research 2013 Annual Meeting.

12 Apr 2013

Brains of different people respond in same way to music, Stanford study says

Do the brains of different people listening to the same piece of music actually respond in the same way? An imaging study by Stanford University School of Medicine scientists says the answer is yes, which may in part explain why music plays such a big role in our social existence.

12 Apr 2013

Illuminating deep mysteries of brain

Researchers at the University of Illinois at Urbana-Champaign and Washington University in St. Louis developed ultrathin, flexible optoelectronic devices - including LEDs the size of individual neurons - that are lighting the way for neuroscientists in the field of optogenetics and beyond.

12 Apr 2013

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

One of the main obstacles that stands in the way of using human hematopoietic stem cells (hHSCs) to treat a variety of diseases is the difficulty growing them in culture—they quickly die or differentiate into other cell types. A series of experiments that demonstrate the successful use of fat cells as part of a feeder layer to support prolonged growth of hHSCs in culture is reported in an article in BioResearch Open Access, a bimonthly peer-reviewed open access journal from Mary Ann Liebert, Inc., publishers.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Updated clinical data from phase I study of Ensituximab presented at AACR meeting

Precision Biologics announced today that in conjunction with researchers from Precsion Biologics , Johns Hopkins Medical Center and Duke University Medical Center presented updated clinical data from the phase I study of Ensituximab, a novel therapeutic antibody to treat pancreas and colorectal cancers

11 Apr 2013

Laboratory News and Research

Scientists use mouse model to identify novel cell surface marker on mammary gland stem cells

Chronic daily pain continues to be burden for limb-injured veterans, says pain management expert

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

Matrix-Bio, Quest Diagnostics enter global licensing agreement for metabolomic biomarkers

Study reveals inner workings of master regulator that controls diverse functions

Researchers use metagenomics to identify the cause of outbreaks of bacterial infection

Researchers identify new potential therapeutic target for lowering cholesterol

Study sheds light on role of microglia during progression of Alzheimer's disease

Sanofi launches large-scale production of artemisinin for malaria

Salk neuroscientists propose how visual system automatically adapts to new environments

Australian, Singapore researchers join hands to combat disease-causing bugs

New research shows safety can be improved for people participating in medical experiments

Newly characterized adenoviruses can cause severe human infections

Researchers identify defective gene responsible for isolated congenital asplenia

Research on soy-based treatment for colorectal cancer presented at AACR annual meeting

Brains of different people respond in same way to music, Stanford study says

Illuminating deep mysteries of brain

Study demonstrates successful use of fat cells to support prolonged growth of human hematopoietic stem cells

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Updated clinical data from phase I study of Ensituximab presented at AACR meeting

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