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Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

A multi-institutional study has revealed that BRAF-positive metastatic malignant melanomas develop resistance to treatment with drugs targeting the BRAF/MEK growth pathway through a major change in metabolism.

11 Mar 2013

NCI-sponsored study to evaluate rosuvastatin for prevention of colon cancer

With March designated as Colorectal Cancer Awareness Month, the North Shore-LIJ Cancer Institute is enrolling people who were recently treated for colon cancer in a polyp prevention study. This National Cancer Institute (NCI)-sponsored study evaluates the cholesterol drug, rosuvastatin (Crestor), as a treatment to reduce the risk of colon cancer.

11 Mar 2013

Einstein researchers to develop drug-impregnated intravaginal ring for HIV prevention in women

Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded a $12 million grant from the National Institutes of Health (NIH) to develop a drug-impregnated intravaginal ring to prevent HIV infection in women.

11 Mar 2013

Drugs that combat ageing may be available within five years

Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher.

11 Mar 2013

New rapid laboratory test successful in identifying GBS colonization in pregnant women

A more rapid laboratory test for pregnant women to detect potentially deadly Group B strep (GBS) has been successful at identifying GBS colonization in six and a half hours, according to the results of a study from The University of Texas Health Science Center at Houston (UTHealth).

11 Mar 2013

Medication use and doctor visits drive up jaw necrosis-related costs

Long-term medication use and follow-up visits are the main drivers affecting costs associated with cancer-related bisphosphonate-associated osteonecrosis of the jaw, report researchers in Oral Diseases.

8 Mar 2013

Researchers uncover cellular-level detail of what happens when bone bears stress over time

From athletes to individuals suffering from osteoporosis, bone fractures are usually the result of tiny cracks accumulating over time -- invisible rivulets of damage that, when coalesced, lead to that painful break.

8 Mar 2013

Weill Cornell receives NIMH grant to discover novel biomarkers for chronic fatigue syndrome

Weill Cornell Medical College has been awarded more than $1.9 million by the National Institute of Mental Health of the National Institutes of Health to lead an innovative research study using advanced neuroimaging and clinical evaluations of patients with chronic fatigue syndrome (CFS).

8 Mar 2013

Chronic obstructive pulmonary disease (COPD) inflammatory subtypes: an interview with Dr Vanessa McDonald, University of Newcastle, Australia

COPD is defined as a preventable and treatable disease associated with significant extrapulmonary consequences that may contribute to severity. The pulmonary component of COPD is characterised by airflow limitation that is not fully reversible. The airflow limitation is usually progressive with an abnormal inflammatory response of the lungs to noxious particles (GOLD Strategy Document). Airflow obstruction in COPD is not highly variable and largely irreversible.

8 Mar 2013

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

In collaboration with colleagues at Cornell University, a team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has discovered cells with stem-cell properties in the ovary that can mutate to form tumors.

8 Mar 2013

Melittin-loaded nanoparticles can destroy human immunodeficiency virus

Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at Washington University School of Medicine in St. Louis have shown.

8 Mar 2013

Southeast Asia's commercial trade plays a central role in spread of amphibian pathogens

A team of scientists led by the Wildlife Conservation Society (WCS) and the National University of Singapore (NUS), revealed in a new study, for the first time, the presence of the pathogenic chytrid fungus (Batrachochytrium dendrobatidis) in amphibians sampled in Singapore. And the American bullfrog may be a central player in the spread of the disease.

8 Mar 2013

SRSF1 protein can prevent cancerous proliferation by stabilizing p53

Some cellular proteins have multiple, and occasionally opposing, functions. Professor Adrian Krainer and colleagues at Cold Spring Harbor Laboratory demonstrate in a paper published online today in Molecular Cell that the oncogenic protein SRSF1 can also trigger a stop in cell growth and prevent cancerous proliferation by stabilizing p53, the powerful tumor-suppressor protein.

8 Mar 2013

Rats sniff each other to signal a social hierarchy and prevent aggressive behavior

Sniffing, a common behavior in dogs, cats and other animals, has been observed to also serve as a method for rats to communicate-a fundamental discovery that may help scientists identify brain regions critical for interpreting communications cues and what brain malfunctions may cause some complex social disorders.

7 Mar 2013

Laboratory News and Research

Combining mitochondrial inhibitors could improve efficacy of BRAF inhibitors in melanoma

NCI-sponsored study to evaluate rosuvastatin for prevention of colon cancer

Einstein researchers to develop drug-impregnated intravaginal ring for HIV prevention in women

Drugs that combat ageing may be available within five years

New rapid laboratory test successful in identifying GBS colonization in pregnant women

Medication use and doctor visits drive up jaw necrosis-related costs

Researchers uncover cellular-level detail of what happens when bone bears stress over time

Weill Cornell receives NIMH grant to discover novel biomarkers for chronic fatigue syndrome

Chronic obstructive pulmonary disease (COPD) inflammatory subtypes: an interview with Dr Vanessa McDonald, University of Newcastle, Australia

Researchers discover ovarian stem-like epithelial cells that can mutate to form tumors

Melittin-loaded nanoparticles can destroy human immunodeficiency virus

Southeast Asia's commercial trade plays a central role in spread of amphibian pathogens

SRSF1 protein can prevent cancerous proliferation by stabilizing p53

Rats sniff each other to signal a social hierarchy and prevent aggressive behavior

Salk epigenetic findings may aid in crop production and study of human diseases

Analysis of anonymized web log data on drugs could be used as early warning system

Genomic analysis could illuminate more options in developing precise treatments for cancer

Study reveals increased dietary salt intake may lead to autoimmune disorders

UCLA scientists discover new genetic risk factor for Alzheimer's disease

Parietal brain cells sort visual information into categories: Study

Lab Diagnostics and Automation - Second Edition eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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