Acute Respiratory Distress Syndrome News and Research

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Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

A new study analyzed whether alveolar epithelial cell necrosis at an early stage SARS-CoV-2 infection and subsequent releases of damage-associated molecular patterns could aggravate COVID-19-associated acute respiratory distress syndrome.

27 Jan 2022

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

The analysis of more than 3,000 lung transplants in the U.S. between Aug. 1, 2020, and Sept. 30, 2021, showed that during the pandemic, 7% of the nation's lung transplants were performed to treat severe, irreversible lung damage caused by COVID-19. More than half of these patients needed ventilators or extracorporeal membrane oxygenation, or ECMO, before their transplant.

27 Jan 2022

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Researchers assess the probability of T-cell apoptosis in patients with severe COVID-19 who were admitted to the hospital.

26 Jan 2022

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

A new study looks at the molecular level inhibition of the protective CFTR gene by the SARS-CoV-2 spike protein.

25 Jan 2022

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Researchers published a study exploring the possibilities of predisposing men for a life-threatening disease course of COVID-19.

24 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

A new study discusses the activation of the complement system to determine its role in COVID-19-related deaths.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

New model to identify biological markers in patients with COVID-19 and other illnesses

Investigators who recently developed a mathematical model that indicated why treatment responses vary widely among individuals with COVID-19 have now used the model to identify biological markers related to these different responses.

17 Jan 2022

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Northwestern Medicine scientists developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which line blood vessel walls.

16 Jan 2022

Microbial characteristics of COVID-19

To better understand how the disease progresses, a recent paper in the journal Frontiers in Medicine discusses the role of the human microbiota in this condition.

13 Jan 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Addition of wound care nurse to prone-positioning team reduces the odds of pressure injuries in patients

The addition of a certified wound and skin care nurse to a multiprofessional prone-positioning team at Penn Medicine Princeton Health significantly reduced the odds of patients with COVID-19 developing pressure injuries, according to a study published in American Journal of Critical Care.

5 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

Acute Respiratory Distress Syndrome News and Research

Early-stage alveolar epithelial cell necrosis linked to COVID-19-induced acute respiratory distress syndrome

Cedars-Sinai experts conduct a national analysis on COVID-19 lung transplants

T-cell apoptosis linked to poor prognosis among COVID-19 patients

Spike-mediated CFTR inhibition accounts for airway inflammation in COVID-19

Exploring loss of Y chromosome in white blood cells as a risk-factor of life-threatening COVID-19 in men

Genetic marker linked to higher risk of death in COVID-19 patients

Direct effect of SARS-CoV-2 on the kidney

SARS-CoV-2 interacts with heparan sulfate to activate the alternative pathway

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

New model to identify biological markers in patients with COVID-19 and other illnesses

Genome editing in vascular endothelial cells made possible with a powerful new delivery system

Microbial characteristics of COVID-19

Role of leptin in immune modulation and pathophysiology of COVID-19

Addition of wound care nurse to prone-positioning team reduces the odds of pressure injuries in patients

Unique nanoparticle can deliver genome editing technology to endothelial cells

SARS-CoV-2 omicron variant may be less severe than the delta variant

An integrated computational methodology for COVID drug prioritization

Booster dose of mRNA vaccines found crucial in protecting against SARS-CoV-2 Omicron variants

Double-dose mRNA COVID vaccines effective among dialysis patients

Structural blueprint of nanoparticles developed to target neutrophils responsible for acute lung inflammation

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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