Cardiomyopathy News and Research

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Cardiomyopathy is a group of diseases with primary, usually diffuse, involvement of the myocardium. The myocardial disease is not secondary to ischaemic, valvular, congenital or pericardial disease.

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

A previously healthy infant who suffered aborted sudden cardiac death was found to have a de novo genetic mutation in the SOS1 gene.

17 Aug 2021

Racial and ethnic disparities in maternal deaths in the U.S. may be larger than previously reported

Racial and ethnic disparities in maternal mortality — deaths related to pregnancy or childbirth — in the United States may be larger than previously reported, suggests a study funded by the National Institutes of Health.

12 Aug 2021

Cardioprotective role of HIF1α in COVID-19 patients

The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which first emerged in Wuhan, China, in late December 2019, has quickly become the most urgent issue facing scientists worldwide. It has been reported that the respiratory infection causes cardiac dysfunction in 25-55% patients, including hospitalized patients and non-critical patients.

10 Aug 2021

Genetic testing in ambulatory cardiology clinics can benefit many patients

A person's genetics may hold the key to early intervention in cardiovascular disease, leading to better outcomes in patient care.

9 Aug 2021

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Results of a compassionate-use study released in STEM CELLS Translational Medicine show promising results for treating muscular dystrophies with mesenchymal stem cells (MSCs) derived from Wharton's jelly (WJ), a substance found in the umbilical cord. Led by doctors at Klara Medical Center (KMC), Czestochowa, Poland, these WJ-MSC treatments resulted in significant improvement in several body muscles in most of the patients, with no serious side effects.

27 Jul 2021

Return to play can be managed for athletes with genetic heart diseases, study suggests

Receiving the diagnosis of a genetic heart disease such as long QT syndrome, which can cause sudden cardiac death, has long been a game-ender for young athletes. But a 20-year study at Mayo Clinic following such athletes who were allowed to return to play suggests that the risks can be managed through a shared decision-making process.

27 Jul 2021

3D-bioprinted cardiac patches show therapeutic, regenerative potential for treating ischemic cardiomyopathy

Cardiovascular diseases account for 32% of global deaths. Myocardial infarction, or heart attacks, play a large part in heart diseases and the necrosis of cardiac tissue after blood supply is decreased or stopped.

27 Jul 2021

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Hematopoietic cell transplantation (HCT) is a recognized treatment option for certain blood and bone marrow cancers as well as some autoimmune and hereditary disorders.

23 Jul 2021

Study could help improve care for irregular heartbeats in patients with hypertrophic cardiomyopathy

New research will help doctors identify, treat and prevent potentially dangerous irregular heartbeats in patients with hypertrophic cardiomyopathy (HCM), a common heart condition in which the heart thickens and strains to pump blood.

15 Jul 2021

Study highlights burden of methamphetamine-associated heart failure hospitalizations in California

Heart failure hospitalizations and costs related to methamphetamine use jumped sharply over a decade in California, according to new research published today in Circulation: Cardiovascular Quality and Outcomes, an American Heart Association journal.

14 Jul 2021

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Now, a new systematic review has been published in the journal Animals that focuses on the clinical symptoms in felines diagnosed with SARS-CoV-2 worldwide.

13 Jul 2021

Women at higher risk of post-COVID-19 syndrome

To better understand post-COVID sequelae, researchers at the University Hospital Basel and the University Hospital Zurich conducted a multicentre prospective observational cohort study.

8 Jul 2021

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

A recent study discusses the efficacy of an AI-enhanced ECG technique that has been used to diagnose left ventricular dysfunction in COVID-19 patients.

17 Jun 2021

Myocarditis after SARS-CoV-2 vaccine

A group of Italian researchers has published a study in the Canadian Journal of Cardiology (CJC), that explores a rare case of progressive dyspnea and constrictive retrosternal pain after a SARS-CoV-2 vaccine.

17 Jun 2021

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Severe childhood restrictive cardiomyopathy is a condition that causes the muscles in the walls of the heart to become stiff, so that the heart is unable to fill properly with blood.

17 Jun 2021

Cell therapy improves outcomes for heart failure patients, clinical trial shows

A clinical trial conducted at the University of Louisville has shown for the first time that heart failure treatments using cells derived from the patient's own bone marrow and heart resulted in improved quality of life and reduced major adverse cardiac events for patients after one year.

14 Jun 2021

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Diverse messenger RNAs are produced in cells by “alternative splicing.” The Leducq Foundation is now supporting a transatlantic network dedicated to investigating this process in heart muscle cells and how changes in this process contribute to disease. Professor Michael Gotthardt of the MDC and Professor Leslie Leinwand of the University of Colorado Boulder are coordinating the project.

14 Jun 2021

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

Researchers from the US recently conducted a study to examine the clinical course and echocardiographic and lab testing across clinically defined fulminant and non-fulminant COVID-19 myocarditis. This study is published on the preprint server, medRxiv.*

11 Jun 2021

New cell-penetrating peptide may protect against life-threatening microbial inflammation

A cell-penetrating peptide developed by researchers at Vanderbilt University Medical Center can prevent, in an animal model, the often-fatal septic shock that can result from bacterial and viral infections.

9 Jun 2021

Are women more likely to develop long COVID?

Researchers found different groups of symptoms persisting after coronavirus disease 2019 (COVID-19), with fatigue and higher IL-6 levels common in women. About 75% of the patients they treated were women, indicating a link between sex hormones and immune response.

8 Jun 2021

Cardiomyopathy News and Research

Further Reading

Infantile sudden death associated with a de novo genetic mutation in the SOS1 gene

Racial and ethnic disparities in maternal deaths in the U.S. may be larger than previously reported

Cardioprotective role of HIF1α in COVID-19 patients

Genetic testing in ambulatory cardiology clinics can benefit many patients

Umbilical cord-derived mesenchymal stem cells show promise to treat muscular dystrophies

Return to play can be managed for athletes with genetic heart diseases, study suggests

3D-bioprinted cardiac patches show therapeutic, regenerative potential for treating ischemic cardiomyopathy

Pre-transplant cardio-cerebrovascular diseases impact hematopoietic cell transplant outcomes

Study could help improve care for irregular heartbeats in patients with hypertrophic cardiomyopathy

Study highlights burden of methamphetamine-associated heart failure hospitalizations in California

Review details clinical signs of SARS-CoV-2 infection in domestic and wild cats

Women at higher risk of post-COVID-19 syndrome

AI ECG as a novel noninvasive approach to diagnosing cardiac injury in COVID-19 patients

Myocarditis after SARS-CoV-2 vaccine

New mouse model mimics human pathology of childhood restrictive cardiomyopathy

Cell therapy improves outcomes for heart failure patients, clinical trial shows

Leducq Foundation provides $7 million to support Cardiac Splicing as a Therapeutic Target project

Cross-sectional study explores differences in biomarkers in fulminant and non-fulminant COVID-19 myocarditis

New cell-penetrating peptide may protect against life-threatening microbial inflammation

Are women more likely to develop long COVID?

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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