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Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

A self-amplifying replicon RNA vaccine against SARS-CoV-2 can elicit durable and protective immunity in pigtail macaques, even after neutralizing antibody responses have waned to undetectable levels.

23 Apr 2023

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Researchers explored the protective systemic and mucosal immunity provided by a single dose of a live-attenuated SARS-CoV-2 vaccine candidate.

20 Apr 2023

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Researchers designed a novel messenger ribonucleic acid (mRNA) vaccine component designated BNT162b4.

17 Apr 2023

Pregnant women show unique immune response to COVID-19

Researchers compare the adaptive, innate, and humoral immune responses between pregnant and non-pregnant women with COVID-19.

16 Apr 2023

Antibody response to SARS-CoV-2 is stronger and more durable in infants and young children

Researchers evaluated humoral responses to severe acute respiratory syndrome coronavirus 2 in infants.

15 Apr 2023

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Researchers developed a novel intranasal vaccine candidate for coronavirus disease 2019 (COVID-19).

14 Apr 2023

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Researchers report on the benefits of consuming dietary phenols and their relationship with the intestinal microbiome.

10 Apr 2023

Antepartum vs. postpartum vaccination: which provides the most protection against SARS-CoV-2 in breastfed infants?

Researchers evaluated the efficacy of transplacental transfer of antibodies against SARS-CoV-2 to infants.

10 Apr 2023

Impact of maternal COVID-19 on neonatal brain development

Researchers described two coronavirus disease 2019 (COVID-19) -infected neonate cases.

10 Apr 2023

Air pollution lowers COVID-19 vaccine immune response

In a recent study published in the journal Environmental Health Perspectives, researchers performed a population-level cohort study in Catalonia, Spain, to evaluate the association between exposure to air pollution for a prolonged duration and coronavirus disease 2019 (COVID-19) vaccine-induced antibody response.

9 Apr 2023

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Researchers assess the role of the live-attenuated vaccine sCPD9 in inducing systemic and mucosal immunity against SARS-CoV-2 variants.

6 Apr 2023

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Since the beginning of the COVID-19 pandemic, researchers have been working on mucosal vaccines that can be administered through the nose.

4 Apr 2023

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

In a recent study, researchers assessed serological and mucosal immunity among three differing cohorts.

4 Apr 2023

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

Researchers conduct a cross-sectional survey to estimate SARS-CoV-2 antibodies in children.

3 Apr 2023

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

Researchers reviewed the existing knowledge on the mechanisms through which DNA tumor viruses evade the antiviral immunity mediated through mis-incorporated uracil (U).

3 Apr 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

Study details bacterial agents in 418 ticks extracted from humans in France

In a recent study published in the journal Emerging Infectious Diseases, researchers analyzed ticks that bit humans between January 2014 and March 2021 in France for the presence of bacterial pathogens.

27 Mar 2023

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

In a recent study posted to the medRxiv* preprint server, researchers examined associations between coronavirus disease 2019 (COVID-19) outcomes and mucosal antibody responses against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and viral RNA levels in pregnant individuals.

22 Mar 2023

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Researchers assess SARS-CoV-2 spike protein-specific immunological memory among unvaccinated and vaccinated convalescents.

22 Mar 2023

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

Memory B cells play a critical role to provide long-term immunity after a vaccination or infection. In a study published in the journal Immunity, researchers describe a distinct and novel subset of memory B cells that predict long-lived antibody responses to influenza vaccination in humans.

22 Mar 2023

Immunoglobulin News and Research

Novel self-amplifying RNA vaccine confers durable protection against COVID-19, reduces viral shedding in primate study

Protective mucosal and systemic immunity provided by a single-dose novel live-attenuated intranasal SARS-CoV-2 vaccine candidate

Vaccine component BNT162b4 enhances T-cell immunity against SARS-CoV-2 variants for reduced COVID-19 disease severity

Pregnant women show unique immune response to COVID-19

Antibody response to SARS-CoV-2 is stronger and more durable in infants and young children

Study develops a novel intranasal influenza virus-vectored vaccine for SARS-CoV-2

Antioxidant-rich phenolic compounds: A key to disease prevention, gut health, and brain homeostasis

Antepartum vs. postpartum vaccination: which provides the most protection against SARS-CoV-2 in breastfed infants?

Impact of maternal COVID-19 on neonatal brain development

Air pollution lowers COVID-19 vaccine immune response

Nasal SARS-CoV-2 vaccine outperforms existing vaccines in preclinical trial

Live attenuated nasal vaccine elicits superior immunity to SARS-CoV-2 variants in hamsters

Pre-existing immunity shapes mucosal SARS-CoV-2-specific antibody responses

Pediatric SARS-CoV-2 seroprevalence higher than official case reports

What is currently known about the mechanisms by which DNA tumor viruses evade uracil-mediated antiviral immunity?

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Study details bacterial agents in 418 ticks extracted from humans in France

Dampened mucosal response against SARS-CoV-2 in pregnant individuals

SARS-CoV-2 infection enhances vaccine-induced immunological memory against spike protein

Novel subset of memory B cells predicts long-lived antibody responses to influenza vaccination

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