Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

New app helps patients with alcohol-related liver disease recover, saves lives

A mobile phone app which helps patients with alcohol-related liver disease to stay sober could help save hundreds of lives every year, according to researchers from UCL and the Royal Free Hospital who developed the app.

5 Jan 2024

Gut microbes revealed as key players in liver disease solutions

In the editorial published on 4 September 2023, in the "gut-liver axis" special issue of the journal Hepatobiliary & Pancreatic Diseases International, Dr. Jian-Gao Fan and Dr. Lu Jiang from Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine provided a comprehensive elucidation of the pivotal role of gut microbiota in various liver diseases.

4 Jan 2024

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Chronic liver disease, a growing threat to global health, often progresses silently in its early stages.

4 Jan 2024

Exploring the global health challenge of hepatitis D

Review explores the global impact of the hepatitis D virus (HDV) on public health, detailing its transmission, clinical course, diagnosis, and treatment options.

2 Jan 2024

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

Very early in the COVID-19 pandemic clinical trials in patients hospitalized with COVID-19 confirmed that corticosteroids like dexamethasone reduced mortality, but they were harmful when applied at the first COVID-19 symptoms, due to the weakening of innate antiviral immunity, leading to delayed viral clearance and adverse outcomes in severe viral pneumonias.

28 Dec 2023

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Research pioneer Dr. Daniel Drucker has much to be proud of, as the GLP-1-based diabetes drugs hailing from his early research are named 2023 breakthrough of the year by the Science Magazine.

18 Dec 2023

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Researchers investigated associations between alcohol consumption behaviors, diabetes mellitus, genetic predispositions, and ARLD incidence in 312,59 active drinkers from the United Kingdom Biobank.

18 Dec 2023

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Science has named the development of glucagon like peptide-1 (GLP-1) agonists and this year's discovery that these drugs can blunt obesity-associated health problems as its 2023 Breakthrough of The Year.

15 Dec 2023

Study points to binge drinking and genetics as key factors in liver disease

Those who binge drink and have a certain genetic makeup are six times more likely to develop alcohol-related cirrhosis, according to new research from UCL, the Royal Free Hospital, the University of Oxford and the University of Cambridge.

14 Dec 2023

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Study in the International Journal of Obesity reveals that BMAL1 deletion in mice protects against obesity and non-alcoholic fatty liver disease caused by a high-fat diet, highlighting its potential as a therapeutic target.

13 Dec 2023

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

The current class of anti-obesity drugs is proving remarkably effective at removing excess pounds. However, a phase 3 randomized clinical trial led by researchers at Weill Cornell Medicine and NewYork-Presbyterian found that people who stopped taking the medication regained much of that weight within a year.

11 Dec 2023

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by excessive hepatic lipid accumulation, poses a high prevalence and can progress to cirrhosis and liver cancer.

11 Dec 2023

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

The associations between meat and fish consumption and the risk of non-alcoholic fatty liver disease (NAFLD).

11 Dec 2023

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Using machine learning, researchers successfully distinguished factors of healthy aging from chronic disease risks by analyzing health data across various ages, finding key markers like neutrophil counts and alkaline phosphatase levels as early indicators of healthy aging.

10 Dec 2023

Study explores the intricate gut-brain-liver connection and its impact on health

Study reviews the gut-brain-liver axis, revealing the complex interplay between these organs in health and disease and the implications for therapeutic interventions, focusing on how gut microbiota affects liver and brain health.

10 Dec 2023

Study identifies new target for fatty liver disease treatment

The global rise in obesity and diabetes is leading to an epidemic in fatty liver disease affecting 20-30 per cent of the world's population.

7 Dec 2023

Novel stem cell treatment could revolutionize liver disease management

Mortality related to end stage liver disease is ranked as the 12th most common cause of death in the U.S. Liver transplantation remains the only treatment for end stage liver disease, but there is a critical shortage of organ donors, necessitating a dire need for new forms of treatment.

7 Dec 2023

New insights into the cellular programs that promote resolution of inflammation during aging

Aging is associated with chronic, nonresolving inflammation, or "inflammaging," that can lead to tissue dysfunction.

6 Dec 2023

Ethnic disparities in COVID-19 mortality rates among hospitalized patients in California

The association between race and outcomes in Coronavirus Disease-2019 (COVID-19) hospitalizations in California.

6 Dec 2023

Sympathetic nervous system and immune interplay: Key to metabolic regulation

A review in Advanced Science explores the interaction between the immune system and the sympathetic nervous system in regulating vital metabolic organs like the pancreas, liver, and adipose tissues. This comprehensive analysis provides insights into the neuroimmune relationships affecting metabolism, offering potential new therapeutic strategies for metabolic diseases.

5 Dec 2023

Liver Disease News and Research

Further Reading

New app helps patients with alcohol-related liver disease recover, saves lives

Gut microbes revealed as key players in liver disease solutions

CLivD score shows promise in early detection of steatotic liver disease and advanced fibrosis

Exploring the global health challenge of hepatitis D

New non-steroidal anti-inflammatory can inhibit the cytokine storm and preserve innate immunity

From diabetes drug to anti-inflammation powerhouse: The unexpected evolution of GLP-1

Study shows synergistic effects of genetic factors, binge drinking, and diabetes in alcohol-related cirrhosis

Science’s Breakthrough of the Year: GLP-1 agonists can blunt obesity-associated health problems

Study points to binge drinking and genetics as key factors in liver disease

Study finds key gene deletion shields mice from diet-induced obesity and liver disease

Tirzepatide maintains weight loss and improves cardiometabolic health in SURMOUNT-4 trial

Intestine epithelium-derived exosomes serve as novel mediator in regulating hepatic lipid metabolism

Is there an association between meat and fish consumption and non-alcoholic fatty liver disease?

Machine learning reveals key markers for healthy aging, separate from chronic disease risks

Study explores the intricate gut-brain-liver connection and its impact on health

Study identifies new target for fatty liver disease treatment

Novel stem cell treatment could revolutionize liver disease management

New insights into the cellular programs that promote resolution of inflammation during aging

Ethnic disparities in COVID-19 mortality rates among hospitalized patients in California

Sympathetic nervous system and immune interplay: Key to metabolic regulation

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