Renal Failure News and Research

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Renal failure or kidney failure is where the kidneys fail to function adequately. Renal failure is divided in acute and chronic forms; either form may be due to a large number of other medical problems.

Novel easy-to-use tool holds potential to revolutionize delirium care in ICU

Millions of intensive care unit patients in the United States experience delirium, an acute brain failure resulting in confusion and long-term memory problems.

14 Mar 2017

Study finds 78% postoperative stroke reduction with ‘no-touch’ beating heart bypass surgery

A landmark study led by Prof. Michael P. Vallely, MBBS, PhD, FRACS, of Sydney Heart and Lung Surgeons and the University of Sydney will be published in the February 28, 2017 issue of the Journal of the American College of Cardiology.

27 Feb 2017

Prolonged use of popular heartburn drugs linked to silent, gradual kidney damage

Taking popular heartburn drugs for prolonged periods has been linked to serious kidney problems, including kidney failure.

22 Feb 2017

Study shows physicians in pediatric ICUs do not use newest guidelines to diagnose AKI in children

A study by University at Buffalo researchers has shown that physicians in pediatric intensive care units are not using the newest guidelines to diagnose acute kidney injury (AKI) in critically ill children, a practice that could affect their patients' long-term health.

27 Oct 2016

IPC PAS researchers develop new polymer that may detect early stages of kidney disease

The advanced phase of acute kidney injury can be fatal in even one in two patients. Fortunately, now it will be possible to detect the disease in its initial stages, when treatment is still relatively simple and the prognosis good.

13 Oct 2016

Novel biomarkers enhance power to predict therapeutic efficacy in LN prognostic models

Results of preclinical studies by investigators at the Medical University of South Carolina reported in the August 2016 issue of Arthritis & Rheumatology demonstrate for the first time that including novel biomarkers in lupus nephritis (LN) prognostic models significantly increases their power to predict therapeutic efficacy.

12 Oct 2016

Non-contrast MRA can be viable diagnostic alternative for patients with chronic kidney disease

Patients with diabetes or renal failure are at high risk for deadly and debilitating vascular diseases, however, the most common imaging tool to evaluate the blood vessels uses a contrast agent that can further damage the kidneys.

30 Sep 2016

Clinical scientists find new way to treat hypertension

A team of clinical scientists at the University of Bristol have found a new way to treat high blood pressure (hypertension).

16 Sep 2016

Researchers identify potential new way of treating hypertension

Researchers eyeing first new anti-hypertensive drug treatment strategy in more than 15 years.

6 Sep 2016

Study provides key insights for effective treatment of individuals with HFpEF

The number of patients hospitalized with HFpEF is now comparable to those with traditional heart failure with a reduced ejection fraction (HFrEF) and is projected to exceed that of HFrEF within the next few years.

27 Jul 2016

Aggressive home blood pressure monitoring may contribute to rise in emergency department visits

Visits to emergency departments for patients with hypertension increased by 64 percent between 2002 and 2012 while hospitalizations for those visits declined by 28 percent.

7 Jul 2016

European Commission approves extended indication for Amgen's Kyprolis (carfilzomib) for the treatment of relapsed multiple myeloma patients

Amgen has announced that the European Commission (EC) has approved a variation to the marketing authorization for Kyprolis® (carfilzomib) to include use in combination with dexamethasone alone for adult patients with multiple myeloma who have received at least one prior therapy. The extended indication marks the second approval for Kyprolis by the EC in less than a year.

6 Jul 2016

First-line nivolumab promising in advanced NSCLC

Phase I results published in the Journal of Clinical Oncology suggest that nivolumab, either given alone or alongside platinum-based doublet chemotherapy, could have a role in the first-line treatment of advanced non-small-cell lung cancer.

5 Jul 2016

Study highlights need to improve end-of-life care for all patients with serious illnesses

Historically, efforts to improve end-of-life care have focused primarily on patients with cancer. But few studies have looked at the quality of end-of-life care for patients with other serious illnesses, such as lung, kidney or heart failure or dementia.

27 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

9 Jun 2016

Mortality risk proportional to PPM severity in aortic value surgery

Prosthesis-patient mismatch during surgical aortic valve replacement is associated with a perioperative mortality risk that increases with increasing PPM severity, study findings indicate.

3 Jun 2016

Chronic use of antacid drugs may speed up aging of blood vessels

Chronic use of some drugs for heartburn and gastroesophageal reflux (GERD) speeds up the aging of blood vessels, according to a published paper in Circulation Research, an American Heart Association journal.

11 May 2016

Long-term Warfarin use may increase dementia rates in AF patients

A new study of more than 10,000 patients treated long term with the blood thinner, Warfarin, reveals higher rates of dementia for patients with atrial fibrillation versus non-AF patients

5 May 2016

Long-term use of herbal remedies may not guarantee safety

Millions of people around the world use herbal health remedies, following a tradition that began millennia ago. Many believe that herbs are safe because they have been used for many years, but researchers from Baylor College of Medicine and Stony Brook University are raising awareness that long-term use of herbal remedies is no guarantee of their safety. The invited commentary appears in EMBO reports.

4 May 2016