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Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

Genkyotex, the leading developer of selective NOX enzyme inhibitors, announced today the initiation of a multinational Phase II clinical study of GKT137831 in patients with diabetic nephropathy.

5 Nov 2013

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

AMP will host its largest ever annual meeting next week with an expected attendance of more than 1,700 molecular diagnostic professionals plus 1,300 representatives from more than 180 exhibiting companies. With more than 25 hours of educational sessions and 350 poster presentations, the AMP 2013 Annual Meeting is the premier source for educational information on all things molecular.

5 Nov 2013

Research findings could offer new insights into how defective cells can multiply in diseases

A rudimentary form of life that is found in some of the harshest environments on earth is able to sidestep normal replication processes and reproduce by the back door, researchers at The University of Nottingham have found.

5 Nov 2013

Offspring born to stressed mothers show stress-induced changes

Children of survivors of extremely stressful life events face adjustment challenges of their own, as has been most carefully studied among the children of Nazi Death Camp survivors. This "intergenerational" transmission of stress response has been studied predominately from the psychological perspective. However, recent research points to biological contributions as well.

5 Nov 2013

Researchers identify factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet (LMU) in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

5 Nov 2013

Computer-aided image analysis provides "second opinion" to identify breast tumor

Researchers at the University of Chicago are developing computer-aided diagnosis (CADx) and quantitative image analysis (QIA) methods for mammograms, ultrasounds and magnetic resonance images (MRIs) to identify specific tumor characteristics, including size, shape and sharpness, said lead researcher Maryellen Giger, A.N. Pritzker Professor of Radiology/Medical Physics and director of the Imaging Research Institute at the University of Chicago.

5 Nov 2013

CHEO-led study confirms validity, reliability of quality of life measurement tool for thalassemia major

A CHEO-led multi-site North American study, headed by Dr. Robert Klaassen, lead investigator at CHEO and associate professor in the University of Ottawa's Department of Pediatrics, has confirmed the validity and reliability of a quality of life measurement tool for children and adults with thalassemia major.

5 Nov 2013

Researchers find crucial step in determining normal aging

For the first time in a large study sample, the decline in brain function in normal aging is conclusively shown to be influenced by genes, say researchers from the Texas Biomedical Research Institute in San Antonio and Yale University.

4 Nov 2013

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

Scientists of the University of Ulm and Columbia University have discovered a diagnostic algorithm to distinguish two subtypes of malignant melanoma. Desmoplastic and spindle cell melanoma may look alike - they often resemble little scars or retractions of the skin - but differ in prognosis and therapeutic options.

4 Nov 2013

Researchers study quality, effectiveness and safety of generic drugs used to treat depression

Researchers at Washington University School of Medicine in St. Louis are studying the quality, effectiveness and safety of generic drugs used to treat depression.

4 Nov 2013

Gene sequencing reveals mutations in estrogen receptor

Researchers at the University of Michigan Comprehensive Cancer Center have identified a type of mutation that develops after breast cancer patients take anti-estrogen therapies. The mutations explain one reason why patients often become resistant to this therapy.

4 Nov 2013

Scientists find key gene that activates muscle growth

For decades, scientists have searched for treatments for myopathies - genetic muscular diseases such as muscular dystrophy and ALS, also called Lou Gehrig's disease.

4 Nov 2013

LMU researchers identify a factor that promotes metastasis of colon tumors

Tumors become highly malignant when they acquire the ability to colonize other tissues and form metastases. Researchers at Ludwig-Maximilians-Universitaet in Munich have identified a factor that promotes metastasis of colon tumors - and presents a possible target for therapy.

4 Nov 2013

Boehringer Ingelheim's Phase II trial of interferon-free hepatitis C treatment shows promising results

Interim data presented today show that all patients (13/13) who reached their 4-week post-treatment follow-up have undetectable levels of hepatitis C virus (SVR4) after completing a 12-week regimen of faldaprevir, deleobuvir, PPI-668 and ribavirin.

4 Nov 2013

Professor receives March of Dimes Agnes Higgins Award for research on maternal-fetal nutrition

A researcher who showed that what a woman consumes during pregnancy may increase her baby's risk of developing a birth defect will receive the March of Dimes Agnes Higgins Award for outstanding achievements in the field of maternal-fetal nutrition.

4 Nov 2013

McMaster University researchers discover how metformin drug works on fat in the liver

About 120 million people around the world with Type 2 diabetes - and two million in Canada - take the drug metformin to control their disease.

4 Nov 2013

Scientists find surprising degree of variation among genomes of individual neurons

It was once thought that each cell in a person's body possesses the same DNA code and that the particular way the genome is read imparts cell function and defines the individual. For many cell types in our bodies, however, that is an oversimplification.

4 Nov 2013

Array BioPharma reports net loss of $0.13 per share for first quarter of fiscal 2014

Array BioPharma Inc. today reported results for the first quarter of its fiscal year ending June 30, 2014.

31 Oct 2013

Scientists uncover new mechanism through which gene expression is regulated

A new study by Weill Cornell Medical College scientists reveals a mechanism through which the expression of genes is controlled -- a finding that highlights genetic mutations that can impair the timing of gene expression.

31 Oct 2013

Scientists explain genetic and molecular basis of diabetes

In two comprehensive studies, scientists from Helmholtz Zentrum München, Ludwig-Maximilians-Universität München and Technische Universität München discovered new associations of two major type 2 diabetes risk genotypes and altered plasma concentrations of metabolic products.

31 Oct 2013

Genetic News and Research

Genkyotex announces initiation of GKT137831 Phase II study in patients with diabetic nephropathy

AMP 2013 to focus on genomics, proteomics, informatics, reimbursement and optimization of patient care

Research findings could offer new insights into how defective cells can multiply in diseases

Offspring born to stressed mothers show stress-induced changes

Researchers identify factor that promotes metastasis of colon tumors

Computer-aided image analysis provides "second opinion" to identify breast tumor

CHEO-led study confirms validity, reliability of quality of life measurement tool for thalassemia major

Researchers find crucial step in determining normal aging

Scientists identify new algorithm to distinguish two subtypes of malignant melanoma

Researchers study quality, effectiveness and safety of generic drugs used to treat depression

Gene sequencing reveals mutations in estrogen receptor

Scientists find key gene that activates muscle growth

LMU researchers identify a factor that promotes metastasis of colon tumors

Boehringer Ingelheim's Phase II trial of interferon-free hepatitis C treatment shows promising results

Professor receives March of Dimes Agnes Higgins Award for research on maternal-fetal nutrition

McMaster University researchers discover how metformin drug works on fat in the liver

Scientists find surprising degree of variation among genomes of individual neurons

Array BioPharma reports net loss of $0.13 per share for first quarter of fiscal 2014

Scientists uncover new mechanism through which gene expression is regulated

Scientists explain genetic and molecular basis of diabetes

Sequencing & Genomics: Elevating Science and Healthcare eBook

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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