Genetic News and Research

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Cancer imaging centers receive £35M grant to develop cutting edge imaging technologies

Cancer imaging is set to get a major boost from a -35 million nationwide initiative to develop cutting edge imaging technologies for basic and clinical cancer research.

25 Oct 2013

Gene-diet interaction may shed light on increased risk of colorectal cancer linked with meat consumption

A newly discovered potential gene-diet interaction for colorectal cancer was reported today (Thursday, Oct. 24) at the American Society of Human Genetics 2013 meeting in Boston.

25 Oct 2013

Whitehead Institute scientists identify novel Parkinson's disease drug target

Using a discovery platform whose components range from yeast cells to human stem cells, Whitehead Institute scientists have identified a novel Parkinson's disease drug target and a compound capable of repairing neurons derived from Parkinson's patients.

25 Oct 2013

New report explains occurrence of breast cancer in women with normal BRCA genes

Since 1994, many thousands of women with breast cancer from families severely affected with the disease have been tested for inherited mutations in BRCA1 and BRCA2. The vast majority of those patients were told that their gene sequences were normal.

25 Oct 2013

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

An international team of scientists has identified an association between heritable, rare mutations in the RINT1 gene and increased risk of early onset breast cancer, according to research reported today (Oct. 24) at the American Society of Human Genetics 2013 annual meeting in Boston.

25 Oct 2013

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

A common genetic variant that affects 1 in 3 people significantly increases the risk of colorectal cancer from the consumption of red meat and processed meat, according to a study presented today at the annual American Society of Human Genetics 2013 meeting, the largest gathering of human geneticists in the world.

25 Oct 2013

Researchers discover novel genetic cause of severe obesity

Researchers from the University of Cambridge have discovered a novel genetic cause of severe obesity which, although relatively rare, demonstrates for the first time that genes can reduce basal metabolic rate - how the body burns calories.

25 Oct 2013

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

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24 Oct 2013

Mckesson's $8.3B Celesio Deal Builds Drug Warehousing Powerhouse

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24 Oct 2013

Biolinerx Inks In-License Agreement With Israeli Institutions For Type 1 Diabetes Treatment

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24 Oct 2013

Study reveals that parental panic disorder affects children

Children of parents with anxiety disorders are more likely to develop anxiety disorders than children of normal controls . This familial aggregation is due to genetic and environmental influences, whereas it can be assumed that shared environmental influences have the greatest effects during childhood, decreasing with age.

24 Oct 2013

Alexion Pharma's replacement therapy gets FDA Breakthrough Therapy designation for MoCD Type A

Alexion Pharma International Sàrl, a subsidiary of Alexion Pharmaceuticals, Inc., today announced that the U.S. Food and Drug Administration has granted a Breakthrough Therapy designation to cyclic pyranopterin monophosphate (cPMP, or ALXN1101), an enzyme co-factor replacement therapy for the treatment of patients with molybdenum cofactor deficiency type A, a severe and life-threatening, ultra-rare, genetic metabolic disorder that causes catastrophic and irreversible neurologic damage within the first weeks of life.

24 Oct 2013

Researchers develop new interactive software game to help children with peanut allergies

Elizabeth McQuaid, Ph.D., a staff psychologist from the Bradley Hasbro Children's Research Center, is leading a research team testing a new interactive software game developed to help children with peanut allergies better manage allergy symptoms, social situations and proper food avoidance.

24 Oct 2013

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

Parkinson's disease continues to puzzle physicians and biologists alike - even though it is well-established that symptoms like muscle tremors, rigidity, and, during the final stages, immobility can all be traced back to the death of a certain type of brain cell called a dopaminergic neuron. The underlying cause of this cellular death is a complex web of interrelated genetic molecular processes as well as external factors, most of the details of which are well-known. But how the various factors correlate and influence each other continues to elude the scientific community.

24 Oct 2013

New Centre for Stratified Medicine opened in Ireland

The University of Ulster has opened a new Centre for Stratified Medicine. The only Centre of its kind in Ireland, £11.5m research facility in Derry~Londonderry puts the University at the forefront of medical research into chronic degenerative diseases.

24 Oct 2013

Scientists find disparities in regulation of transposons between humans and non-human primate cells

Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells, a type of cell that has the ability to form any other cell or tissue in the body.

24 Oct 2013

Older people with diabetes more likely to develop cognitive deterioration and Alzheimer's disease

Diabetes and dementia are rising dramatically in the United States and worldwide. In the last few years, epidemiological data has accrued showing that older people with diabetes are significantly more likely to develop cognitive deterioration and increased susceptibility to onset of dementia related to Alzheimer's disease.

24 Oct 2013

Researchers use nanopores to smuggle DNA or proteins across membranes

A living cell is built with barriers to keep things out - and researchers are constantly trying to find ways to smuggle molecules in.‬ ‪Professor Giovanni Maglia (Biochemistry, Molecular and Structural Biology, KU Leuven) and his team have engineered a biological nanopore that acts as a selective revolving door through a cell's lipid membrane. The nanopore could potentially be used in gene therapy and targeted drug delivery.‬‬‬‬‬‬‬

24 Oct 2013

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Acute dendritic leukaemia is a rare type of leukaemia, but one with the worst prognosis-the average patient survival rate is just 12-14 months-that is difficult to treat. Juan Cruz Cigudosa's team, from the Spanish National Cancer Research Centre's Molecular Cytogenetics Group, has for the first time sequenced the exome -the coding, or protein-generating, regions of the genome- of dendritic cell leukaemia.

24 Oct 2013

Specific antibody patterns predict schizophrenia risk

The presence of antibodies to multiple foods and infectious agents is a risk marker for new-onset schizophrenia, a case-control study suggests.

23 Oct 2013

Genetic News and Research

Cancer imaging centers receive £35M grant to develop cutting edge imaging technologies

Gene-diet interaction may shed light on increased risk of colorectal cancer linked with meat consumption

Whitehead Institute scientists identify novel Parkinson's disease drug target

New report explains occurrence of breast cancer in women with normal BRCA genes

Scientists identify link between rare mutations in RINT1 gene and early onset breast cancer risk

Study identifies gene that raises risk for colorectal cancer from eating red or processed meat

Researchers discover novel genetic cause of severe obesity

DSM, Sanquin Make Factor IX-Recovering Mab Manufacturing Deal

Mckesson's $8.3B Celesio Deal Builds Drug Warehousing Powerhouse

Biolinerx Inks In-License Agreement With Israeli Institutions For Type 1 Diabetes Treatment

Study reveals that parental panic disorder affects children

Alexion Pharma's replacement therapy gets FDA Breakthrough Therapy designation for MoCD Type A

Researchers develop new interactive software game to help children with peanut allergies

LCSB researchers publish current knowledge about the genetic, molecular causes of PD

New Centre for Stratified Medicine opened in Ireland

Scientists find disparities in regulation of transposons between humans and non-human primate cells

Older people with diabetes more likely to develop cognitive deterioration and Alzheimer's disease

Researchers use nanopores to smuggle DNA or proteins across membranes

Study uncovers new genetic pathways that could revolutionise acute dendritic leukaemia treatment

Specific antibody patterns predict schizophrenia risk

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