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The structure of AGT shows how one human protein reduces the potency of chemotherapy

The fine details of this x-ray structure may help scientists find ways to fight certain cancers, such as brain tumors, which express high levels of AGT making them resistant to chemotherapy.

9 Jul 2004

Anal cancer is on the rise in both sexes

Anal cancer is on the rise in both sexes, particularly among American men, and changing trends in sexual behavior — combined with current tobacco use and infection by a specific strain of the human papillomavirus — may help explain the increase.

9 Jul 2004

New leads for the discovery of anthrax antitoxins that could be used in conjunction with antibiotics to treat late-stage anthrax

A team of researchers led by The Burnham Institute’s Robert C. Liddington has determined the crystal structure of the binding complex between anthrax toxin and one of its host receptors.

8 Jul 2004

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined that a particular type of cellular stress called osmotic stress is of critical importance to cell growth and the body’s immune response against infection.

7 Jul 2004

Key proteins that regulate neurofibromatosis could be targets for new drugs

More than 100,000 Americans suffer from the painful and debilitating genetic disorder known as neurofibromatosis, or NF, which causes tumors to grow in various types of nerve tissue throughout the body.

7 Jul 2004

Research points to a possible way to design anthrax toxin molecules that selectively attack tumor cells

Scientists have determined a three-dimensional (3-D) molecular image of how anthrax toxin enters human cells, giving scientists more potential targets for blocking the toxin, the lethal part of anthrax bacteria.

5 Jul 2004

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

Scientists at The Scripps Research Institute have described the regulatory mechanism of an important human protein called Rac that controls a number of biological processes and is directly implicated in several human diseases.

2 Jul 2004

How DNA repair machinery detects and corrects errors in DNA replication

Biochemists at Duke University Medical Center have discovered key components that enable the cell's DNA repair machinery to adeptly launch its action in either direction along a DNA strand to strip out faulty DNA.

2 Jul 2004

Exelixis files new drug application for a proprietary novel anticancer compound

Exelixis, Inc. has submitted an investigational new drug application (IND) to the U.S. Food and Drug Administration (FDA) for XL999, a proprietary novel anticancer compound.

29 Jun 2004

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

Physicians may be able to make early decisions on the best treatment for breast cancer, thanks to research published in Breast Cancer Research today.

28 Jun 2004

50,000 people in the U.S. with cancer, multiple sclerosis, rheumatoid arthritis or hepatitis C will be eligible for a Medicare drug lottery

50,000 people or 10% of the 500,000 people in the U.S with cancer, multiple sclerosis, rheumatoid arthritis or hepatitis C will be eligible for a Medicare drug lottery for coverage of life saving drugs.

26 Jun 2004

First-ever microfluidic BioMEMS device to study the mechanisms of cell migration and deformation

Cancer cells have the ability to invade blood vessels and find their way into the bloodstream. Once there, these infected cells can easily travel to other parts of the body and attack healthy organs.

25 Jun 2004

Ingredient of human breast milk may be a new treatment for warts

New Swedish research suggests that HAMLET or "Human-lactalbumin made lethal to tumor cells" an ingredient of human breast milk may be a new treatment for warts.

24 Jun 2004

Microchip to track genetic signature of cancer and normal tissue

MicroRNAs (miRNAs), tiny pieces of genetic material that can serve as stop signs for gene expression and protein synthesis, are thought to be important in the development of cancer.

23 Jun 2004

Partial breast radiation procedure may benefit cancer patients

Some women with breast cancer who prefer breast conserving surgery consisting of lumpectomy and radiation may choose a procedure that delivers radiation to the malignant tumor and not to the entire breast

23 Jun 2004

Prostate and kidney cancer can be detected in urine

Bladder cancer is the fourth most common male cancer in the Western world. There will be more than 44,6000 new cases of bladder cancer diagnosed in U.S. men this year and more than 15,600 new cases diagnosed in women As many as 25 percent of these cancers are diagnosed after the disease is advanced, leading to a poor prognosis.

23 Jun 2004

Discovery of a gene-expression signature common to distinct types of cancer

Researchers at the University of Michigan, Johns Hopkins and the Institute of Bioinformatics in India have discovered a gene-expression "signature" common to distinct types of cancer

23 Jun 2004

Cognitive decline can occur before chemotherapy treatment

In a series of studies in breast cancer patients, researchers at The University of Texas M. D. Anderson Cancer Center have confirmed the presence of “chemobrain” after chemotherapy treatment – but they also discovered that a significant portion of patients have cognitive declines even before chemotherapy.

21 Jun 2004

Early patient response to Forteo in postmenopausal women with osteoporosis

Changes in markers of bone remodeling after one month of treatment with FORTEO® (teriparatide [rDNA origin] injection) may provide important early evidence of treatment response, according to new data presented today at the 86th Annual Meeting of The Endocrine Society (ENDO).

17 Jun 2004

Xenobiotic gets patent approval for toxin detection

XDS consultant (and former XDS laboratory director) Michael Chu and President George Clark combined their research skills to develop a rapid and relatively inexpensive methodology to quantify TEQs (Toxic Equivalence -- measures of toxicity adopted by the World Health Organization) for individual toxic chemical groups.

17 Jun 2004

Tumor News and Research

The structure of AGT shows how one human protein reduces the potency of chemotherapy

Anal cancer is on the rise in both sexes

New leads for the discovery of anthrax antitoxins that could be used in conjunction with antibiotics to treat late-stage anthrax

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Key proteins that regulate neurofibromatosis could be targets for new drugs

Research points to a possible way to design anthrax toxin molecules that selectively attack tumor cells

Protein called Rac controls a number of biological processes and is directly implicated in several human diseases

How DNA repair machinery detects and corrects errors in DNA replication

Exelixis files new drug application for a proprietary novel anticancer compound

A gene involved in the adhesion of cells is less active in breast tumors with a poor prognosis than those that are less aggressive

50,000 people in the U.S. with cancer, multiple sclerosis, rheumatoid arthritis or hepatitis C will be eligible for a Medicare drug lottery

First-ever microfluidic BioMEMS device to study the mechanisms of cell migration and deformation

Ingredient of human breast milk may be a new treatment for warts

Microchip to track genetic signature of cancer and normal tissue

Partial breast radiation procedure may benefit cancer patients

Prostate and kidney cancer can be detected in urine

Discovery of a gene-expression signature common to distinct types of cancer

Cognitive decline can occur before chemotherapy treatment

Early patient response to Forteo in postmenopausal women with osteoporosis

Xenobiotic gets patent approval for toxin detection

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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