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Technology used for screening liquids can be adapted to provide rapid COVID-19 testing

Loughborough University researchers are hoping a technology they developed to quickly screen liquids for microorganisms can be adapted to provide rapid testing for Covid-19.

24 Nov 2020

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Researchers in New York, USA, have found an association of mortality with an early humoral response to SARS-CoV-2 infection within the first few days after onset of symptoms (DAOS), using a highly sensitive and automated testing-on-a-probe (TOP) biosensor assays for SARS-CoV-2.

24 Nov 2020

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

Avacta Group plc, the developer of innovative cancer therapies and diagnostics based on its proprietary Affimer® and pre|CISION™ platforms, is pleased to announce significant progress in the development of a highly scalable manufacturing process for a lateral flow SARS-CoV-2 antigen test being carried out with BBI Solutions, and that the lateral flow test has very good analytical sensitivity with laboratory samples.

From Avacta Life Sciences Ltd. 24 Nov 2020

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Wastewater surveillance has been reported to be a feasible and efficient way to monitor the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the current COVID-19 pandemic. A recent study draws attention to the need to freeze wastewater samples if the analysis is carried out later rather than immediately.

24 Nov 2020

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Researchers have developed a fluorescent reporter gene-bearing recombinant form of SARS-CoV-2, which is capable of replication.

23 Nov 2020

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

A startling new case study of Chicago, led by a team of researchers at Northwestern University in Illinois, USA, suggests a 16-fold higher incidence of SARS-CoV-2 infection than previously thought. This is judging from seroprevalence (antibody presence blood testing) figures, rather than the number of RT-PCR-positives reported there (via swab sample testing of symptomatic patients).

23 Nov 2020

Speed of test results and frequency of testing are paramount for effective COVID-19 surveillance

For COVID-19 Surveillance, Test Frequency and Turnaround Time Are Paramount, Modeling Suggests Speed of test results and frequency of testing are paramount for effective COVID-19 surveillance, suggests a new study that modeled trade-offs in test sensitivity, test frequency, and sample-to-answer reporting time, in select scenarios.

23 Nov 2020

SARS-Cov-2 antibodies are detected up to 3 months after infection, shows study

A new study in health care workers led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation and the Hospital Clínic of Barcelona, shows that IgA and IgM antibodies to SARS-CoV-2 decay quickly, while IgG antibody levels are maintained for at least three months after infection.

23 Nov 2020

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

A recent study conducted by a team of international scientists has revealed that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative pathogen of coronavirus disease 2019 (COVID-19), suppresses the expression and function of human angiotensin-converting enzyme 2 (ACE2) and induces the expression of interferon-stimulated genes at the initial phase of infection. The study is currently available on the bioRxiv* preprint server.

20 Nov 2020

Texas Heart Institute to participate in a study to treat ARDS in hospitalized COVID-19 patients

Texas Heart Institute has been selected as one of up to 60 sites in the world to participate in an international investigative study seeking to aid COVID-19 patients who develop acute respiratory distress syndrome (ARDS).

19 Nov 2020

Build-up of cellular 'trash' in the brain can cause neurodegeneration, death

A little mess never killed anyone, right? Wrong. Researchers at Tokyo Medical and Dental University (TMDU) have recently shown that a build-up of cellular "trash" in the brain can actually cause neurodegeneration, and even death.

19 Nov 2020

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Researchers from the United States and The Netherlands have conducted a pre-clinical study supporting the initiation of a Phase 3 trial to test a two-dose regimen of the Janssen Ad26.COV2.S vaccine candidate among adult and elderly individuals.

19 Nov 2020

Seroprevalence meta-analysis predicts 643 million already infected by SARS-CoV-2 globally

A recent systematic review and meta-analysis conducted by a team of international scientists reveal low seroprevalence of anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies in the general population.

19 Nov 2020

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

In a recent study, a team of researchers at Northwestern University, USA, had found that nearly 20 percent seroprevalence in the United States metropolitan site, Chicago, over the summer, during a period when lockdown restrictions were eased. They found that three-quarters of seropositive individuals retained detectable antibodies for at least 120 days or four months.

19 Nov 2020

Genetic variations of SARS-CoV-2 transmission in cats

Using cats as an animal model to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission, researchers have determined the virus has a narrow transmission bottleneck.

19 Nov 2020

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

Researchers at Montana State University have validated and compared two methods for inactivating the causative agent of coronavirus disease 2019 (COVID-19) that would enable the virus to be studied at a lower biosafety level (BSL) than the one currently required.

18 Nov 2020

SARS-CoV-2 was circulating in Italy before China recognized its existence

This study, published in the Tumori Journal, sheds light on the possibility that the virus had been spreading in Italy well before the outbreak was officially reported in Wuhan, China.

17 Nov 2020

New multiplex assay can be used for epidemiological surveillance, management of COVID-19

Scientists from Northwell Health Laboratories have developed a new diagnostic multiplex assay that can be used for epidemiological surveillance and clinical management of COVID-19.

17 Nov 2020

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Adding another piece to the puzzle that is coronavirus disease 2019 (COVID-19) serology, a new study published on the preprint server medRxiv* in November 2020 suggests that males have stronger but more transient anti-severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protective immunity than females.

17 Nov 2020

Widespread COVID-19 testing may be possible with new dried blood tests

Researchers have developed dried blood spot sample testing that could be instrumental in preventing the spread of SARS- CoV-2.

17 Nov 2020

Assay News and Research

Technology used for screening liquids can be adapted to provide rapid COVID-19 testing

Biosensor assay SARS-CoV-2 antibody test may predict COVID-19 severity in patients

Avacta Group announces significant progress in the development of SARS-CoV-2 rapid antigen test

SARS-CoV-2 RNA best preserved in wastewater under freezing conditions

Researchers develop recombinant SARS-CoV-2 model to aid vaccine and antiviral research

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

Speed of test results and frequency of testing are paramount for effective COVID-19 surveillance

SARS-Cov-2 antibodies are detected up to 3 months after infection, shows study

SARS-CoV-2 suppresses ACE2 activity in COVID-19 patients

Texas Heart Institute to participate in a study to treat ARDS in hospitalized COVID-19 patients

Build-up of cellular 'trash' in the brain can cause neurodegeneration, death

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Seroprevalence meta-analysis predicts 643 million already infected by SARS-CoV-2 globally

Detectable SARS-CoV-2 antibodies 120 days post-infection in Chicago case study

Genetic variations of SARS-CoV-2 transmission in cats

Optimizing SARS-COV-2 inactivation for COVID-19 research at lower biosafety levels

SARS-CoV-2 was circulating in Italy before China recognized its existence

New multiplex assay can be used for epidemiological surveillance, management of COVID-19

Males may have higher but more transient SARS-CoV-2 immunity than females post-infection

Widespread COVID-19 testing may be possible with new dried blood tests

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