Bioinformatics News and Research

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Bioinformatics is the application of information techniques for the storage, retrieval, and analysis of large quantities of biological data.

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

DePaul University and Rosalind Franklin University of Science and Medicine are funding three faculty research projects that bring together artificial intelligence, biomedical discovery and health care.

27 Jan 2023

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

26 Jan 2023

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Mount Sinai researchers have been awarded $12 million over five years by the National Institutes of Health to create a center to elucidate novel causes of, and contributing factors to, food allergies and atopic dermatitis.

25 Jan 2023

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

In this interview, News Medical spoke to Kate Lawrenson, Ph.D., about their latest research which detailed the molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

19 Jan 2023

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Researchers developed a computational workflow based on molecular dynamic (MD) simulations and artificial neural network (ANN) to assess the SARS-CoV-2 spike (S) protein receptor-binding domain (RBD)-human angiotensin-converting enzyme 2 (hACE2) binding affinities of SARS-CoV-2 variants.

17 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Drug combination elicits efficacious anti-tumor immunity against immunotherapy-resistant cancers

Immunotherapy is a way of treating cancer by reprogramming the patient's immune system to attack their tumor.

10 Jan 2023

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

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From MGI 10 Jan 2023

Study offers novel insights into the elongation dynamics of eukaryotic cells

Life depends on the precise functioning of several proteins synthesized in cells by ribosomes. This diverse set of proteins, known as a proteome, is maintained by the robust translation elongation of amino acid sequences taking place in the ribosomes.

5 Jan 2023

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

4 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

If your alertness and reaction time is see-sawing more than usual, you may be more at risk of a viral illness.

3 Jan 2023

Discovery could pave the way for developing therapies to treat nonalcoholic steatohepatitis

UT Southwestern immunologists have uncovered a key pathogenic event prompted by obesity that can trigger severe forms of nonalcoholic fatty liver disease and potential liver failure.

27 Dec 2022

New methods can advance the development of rapid diagnostics for many infectious diseases

Two companion studies report new artificial intelligence approaches for identification of molecular "fingerprints" for specific infections. The methods, used here to derive a fingerprint for COVID-19, can advance the development of rapid diagnostics for many infectious diseases.

21 Dec 2022

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

The most comprehensive lung cell atlas to date, from the Wellcome Sanger Institute and collaborators, has revealed 11 new lung cell types and offers detailed insight into an immune process involved in fighting lung infections.

21 Dec 2022

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Cleft lip and palate are among the most common congenital malformations, which are mainly due to genetic causes.

16 Dec 2022

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Researchers from the Department of Clinical Oncology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) discovered a novel subtype of Epstein-Barr Virus (EBV)-positive nasopharyngeal carcinoma (NPC) and EBV-associated immunosuppression in the tumor microenvironment (TME).

16 Dec 2022

Next-generation sequencing could change research on sexual assault cases

In this interview, Alexis Garloff talks to NewsMedical about her next-generation sequencing research and the possible applications in forensics, particularly in sexual assault cases.

From Verogen, Inc. 16 Dec 2022

Ceramide blockers prevent the loss of muscle mass during aging in mice

During aging, mice, like humans, become inactive and lose muscle mass and strength. A team of scientists led by Johan Auwerx at EPFL have now discovered that when mice age, their muscles become packed with ceramides.

16 Dec 2022

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, has published a report that was designed to assess clinical adoption, identify classification inconsistencies, and evaluate implementation barriers for the 2017 report, "Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer: A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists.

15 Dec 2022

Bioinformatics News and Research

Further Reading

DePaul and Rosalind Franklin fund research projects that bring together AI, biomedical discovery and health care

Scientists use next-generation protein degradation technology to study CTCF's role in transcription

Mount Sinai scientists earn $12 million to elucidate novel causes of food allergies and atopic dermatitis

Mapping Matters: new cellular atlas of endometriosis for better understanding of the disease

Exploring bioinformatics approach for evaluating binding affinities of probable COVID-19 therapeutic decoys

Machine learning tools help unravel why human accelerated regions evolved so quickly

Drug combination elicits efficacious anti-tumor immunity against immunotherapy-resistant cancers

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

Study offers novel insights into the elongation dynamics of eukaryotic cells

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Subtle variations in every day cognitive performance associated with susceptibility to viral illness

Discovery could pave the way for developing therapies to treat nonalcoholic steatohepatitis

New methods can advance the development of rapid diagnostics for many infectious diseases

Comprehensive lung cell atlas offers insights into an unexpected immune niche in the airways

New mutations near known genes could contribute to the increase in cleft lip and palate risk

Study reveals subtypes and EBV-associated regulatory epigenome reprogramming in nasopharyngeal carcinoma

Next-generation sequencing could change research on sexual assault cases

Ceramide blockers prevent the loss of muscle mass during aging in mice

Assessing clinical adoption of 2017 guidelines for interpretation and reporting of sequence variants in cancer

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