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SH2-B enhances brain's leptin sensitivity - may lead to clues for treatment of obesity and diabetes

What do laboratory mice at the University of Michigan Medical School have in common with millions of overweight Americans? Like many of us, these mice just can't stop eating.

18 Aug 2005

Researchers find drug targets for treating metabolic syndrome

Ongoing studies by researchers at UT Southwestern Medical Center and other institutions have uncovered the biochemical basis of many of the factors contributing to what is known as the metabolic syndrome, suggesting potential new drug targets for treating the condition.

11 Aug 2005

Switching treatment to the drug anastrozole after two years of tamoxifen is beneficial for women with early breast cancer

Switching treatment to the drug anastrozole after two years of tamoxifen can improve eventfree survival for postmenopausal women with early breast cancer, concludes a study in this week’s issue of The Lancet.

4 Aug 2005

Pedometers motivate walkers

Need motivation to walk 10,000 steps? Get a pedometer, says University of Tennessee professor Dixie Lee Thompson.

2 Aug 2005

$New protective drugs called bisphosphonates reduce pain and fractures in metastatic breast cancer$

New protective drugs called bisphosphonates reduce pain and fractures in metastatic breast cancer

When breast cancer spreads to bones, relatively new protective drugs called bisphosphonates can reduce skeletal damage, says a new systematic review of previous studies. While the new treatment approach does not improve survival rates, it can minimize disabling fractures, spinal cord compression and pain.

19 Jul 2005

Potential use of NH neurotransmitters as novel source for psychiatric drugs

Physiologists and medical researchers have long recognized the important endocrine roles played by the pituitary hormones oxytocin (OT) and vasopressin (VP) on peripheral systems in lactation, uterine contraction and urine concentration.

19 Jul 2005

Infertility may be becoming more of a man's problem than a woman's problem

Until now, approximately 40% of infertility cases have been linked to medical problems in men and 40% to medical problems in women, with the remaining 20% due to joint problems.

27 Jun 2005

Minimally invasive approach to removing diseased thyroids

An incision about half the length used for traditional surgery works just as well in removing diseased thyroids, researchers have found.

27 Jun 2005

Scientists prove that human embryonic stem cells can develop in the laboratory into the early forms of cells that eventually become eggs or sperm

Their work opens up the possibility that eggs and sperm could be grown from stem cells and used for assisted reproduction, therapeutic cloning and the creation of more stem cells for further research and for the improved treatments for patients suffering from a range of diseases.

19 Jun 2005

IGF-based growth hormone dosing could become a novel paradigm in treating growth hormone deficiency

A randomized University of California - Los Angeles (UCLA) study found that a new dosing paradigm can improve height outcomes in the treatment of children who have short stature due to growth hormone deficiency and idiopathic short stature.

6 Jun 2005

Latest research on men's health issues, treatments and lifestyle practices

Today, leading researchers are gathering at the annual meeting of The Endocrine Society in San Diego to present the latest research on men's health issues, treatments and lifestyle practices. New findings could help doctors identify risks and treat men's conditions more effectively.

6 Jun 2005

Suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer

A modest suppression of growth hormone and related compounds beginning in early adulthood may delay the onset or progression of several types of cancer, researchers from Wake Forest University School of Medicine and other centers reported today at ENDO 2005, the annual meeting of the Endocrine Society, in San Diego.

5 Jun 2005

Toxic chemicals that poisoned your great-grandparents may also damage your health

New U.S. research is suggesting that chemicals can change the way genes work and that toxic chemicals that poisoned your great-grandparents may also damage your health.

5 Jun 2005

Role of toxins in inherited disease

A disease you are suffering today could be a result of your great-grandmother being exposed to an environmental toxin during pregnancy.

3 Jun 2005

Babies show effects of mothers stress from 9/11 trauma

Pregnant women present during the September 11 World Trade Center collapse have passed on markers of Post Traumatic Stress Disorder (PTSD) to their unborn babies through transgenerational transmission. The findings strengthen the evidence for in utero or early life risk factors for the later development of adult mental or physical disorders.

3 May 2005

Body's 24-hour internal clock linked to obesity and diabetes

Obesity and diabetes in both adults and children are rising at alarming rates and a wide range of culprits -- super-sized food portions, lack of exercise due to television, computers, suburban sprawl and loss of gym classes, high-fat and fast foods, sugar-laden drinks and psychological trauma -- have been blamed.

21 Apr 2005

Babies who gain weight rapidly during their very first week of life may be more likely to be overweight as young adults

Researchers from The Children's Hospital of Philadelphia, the University of Pennsylvania and the University of Iowa studied 653 adults, ranging in age from 20 to 32. The subjects, all of whom were white, had been measured as newborns while participating in infant formula studies in Iowa. Those who had gained weight more rapidly during their first week were significantly more likely to be overweight decades later.

19 Apr 2005

Polycystic ovary syndrome increases chance of developing cardiovascular disease

Women who suffer from polycystic ovary syndrome (PCOS), one of the most common causes of female infertility in the U.S., have an increased chance of developing cardiovascular disease, according to a new study published this month in The Journal of Clinical Endocrinology & Metabolism, published by The Endocrine Society.

6 Apr 2005

Alcohol consumption by women who are breast feeding reduces their milk supply

Scientific researchers have turned folklore on its head by showing that alcohol consumption by women who are breast feeding reduces their milk supply, rather than boosting it.