Pancreas News and Research

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The pancreas is a gland organ in the digestive and endocrine system of vertebrates. It is both an endocrine gland producing several important hormones, including insulin, glucagon, and somatostatin, as well as an exocrine gland, secreting pancreatic juice containing digestive enzymes that pass to the small intestine. These enzymes help in the further breakdown of the carbohydrates, protein, and fat in the chyme.

Oral medications may control symptoms of Type II diabetes in children just as well as insulin injections

According to the medical records of 26 children diagnosed with the disease, oral medications reduced levels of a compound in the blood called hemoglobin A1C by an average of 2 percentage points.

15 Aug 2005

DNA chip technology helps with discovery of new type 2 diabetes gene

In a new study appearing in the August 12 issue of the journal Cell, the investigators first identified genes that were altered in their level of expression in islets isolated from people with type 2 diabetes.

13 Aug 2005

Rochester Institute of Technology showcases landmark medical imaging project

Using revolutionary medical imaging technology, researchers at Rochester Institute of Technology are providing a better understanding of the human body and its many secrets.

11 Aug 2005

Placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases as embryonic stem cells

Routinely discarded as medical waste, placental tissue could feasibly provide an abundant source of cells with the same potential to treat diseases and regenerate tissues as their more controversial counterparts, embryonic stem cells, suggests a University of Pittsburgh study to be published in the journal Stem Cells and available now as an early online publication in Stem Cells Express.

10 Aug 2005

In vivo engineering of organs: The bone bioreactor

An international team of biomedical engineers has demonstrated for the first time that it is possible to grow healthy new bone reliably in one part of the body and use it to repair damaged bone at a different location.

25 Jul 2005

New research finds molecular link between obesity and diabetes

Researchers say they have discovered a molecular link between obesity and type 2 diabetes, and the link could be a potential target for new drugs to treat the disease.

21 Jul 2005

Protein found in fat cells is a newly discovered cause of insulin resistance

A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) has shown that a protein found in fat cells is a newly discovered cause of insulin resistance, establishing a previously unidentified molecular link between obesity and type 2 diabetes and offering a potential new target for the development of drugs to treat diabetes.

20 Jul 2005

Metformin should be in the first line of defense against type 2 diabetes

A new review of studies confirms that the drug metformin should be in the first line of defense against type 2 diabetes. Using metformin alone can improve control of blood glucose, while also reducing risk factors for heart disease such as excess body weight, cholesterol levels and hypertension, the review found.

20 Jul 2005

Insulin keeps fat in the liver under control

Insulin, a hormone long recognized as a generator of fat, also keeps fat in the liver under control, according to a new study in the July issue of Cell Metabolism.

19 Jul 2005

Functional analysis of human hematopoietic stem cell gene expression using zebrafish

What do you get when you mix RNA chips and zebrafish? A new two-stage method for studying human gene expression differs in human stem cells and progenitor cells, according to a new article in the open access journal PLoS Biology.

6 Jul 2005

Takeda Pharmaceuticals submits NDA for a new oral diabetes medication

Takeda Pharmaceuticals North America today announced that the company has submitted a New Drug Application (NDA) for a new oral medication that combines pioglitazone HCl and glimepiride, a sulfonylurea, to the United States Food and Drug Administration (FDA) for the treatment of type 2 diabetes.

30 Jun 2005

Experimental drug for diabetes looks promising

Encouraging results in a small study, with a new experimental treatment, promises help for certain diabetics to retain some ability to make their own insulin.

29 Jun 2005

Saturated fats combined with genetic trait may make people more susceptible to type 2 diabetes

A University of Alberta team of researchers has discovered an additional 2 million Canadians who have a high fat diet or are overweight may be at increased risk for developing type 2 diabetes if they carry a particular type of common specific genetic trait known as a polymorphism.

29 Jun 2005

Exercise helps find genetic regions linked to prediabetes

People's bodies respond to exercise in different ways, and their genetic makeup is partly responsible.

28 Jun 2005

New drug delays the onset of diabetes

New research has shown that an experimental drug, designed to reset the body's immune system, could delay the need for extra insulin in some people with recently diagnosed juvenile diabetes.

23 Jun 2005

Muraglitazar lowers blood glucose and helps dyslipidemia seen in diabetes

A novel compound provides long-term lowering of blood glucose levels and improves plasma lipids (fats) that are often a problem in people with type 2 diabetes -- all in a once-daily pill, according to a report presented today at the American Diabetes Association's 65th Annual Scientific Sessions.

12 Jun 2005

Genetic variations predispose Mexican Americans to insulin resistance

Although numerous studies have shown that low-grade inflammation is linked to heart disease and diabetes, more recent studies have shown that inflammation plays a role in insulin resistance, a syndrome that leads to diabetes and heart disease and affects about one in four adults in the United States.

12 Jun 2005

Lorus Therapeutics receives patent allowance to protect novel anticancer drug

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc. (GeneSense), has received notice from the European Patent Office of its intention to grant GeneSense's application for a patent of its novel antisense drug, GTI-2501.

9 Jun 2005

Three pancreatic islet cell transplants successfully treat type 1 diabetic woman

A Davidson woman has been successfully treated for her Type 1 diabetes through a procedure performed at Carolinas Medical Center. Paul F. Gores, M.D., has led a multi-disciplinary team through a series of three pancreatic islet cell transplants since the summer of 2003. The result is a patient who is now insulin-free.

8 Jun 2005

New gene shows way for autoimmune disease

A new gene suspected to contribute to autoimmune diseases such as type 1 diabetes and lupus - a condition in which the body’s own immune system attacks organs such as the kidneys and skin - has been discovered by Australian National University (ANU) immunologists.

30 May 2005