Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

New target for diagnosis and treatment of ovarian cancer

An RNA-binding protein that is overproduced in ovarian cancer may present a new target for diagnosis or treatment of ovarian and other cancers, according to researchers at the University of Illinois at Chicago.

10 Apr 2007

Scientists identify protein key to breast cancer spread

(PHILADELPHIA) Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread.

10 Apr 2007

Scientists link treatment-induced growth factor to cancer spread

In advanced cancer, anti-tumor therapies often work only partially or not at all, and tumors progress following treatment.

7 Apr 2007

TGF-beta inhibitors stop tumors spreading to new sites

For several types of cancer, persistently high levels of the soluble factor TGF-beta in the blood after surgery, chemotherapy, or radiation therapy correlate with increased risk of early metastasis and a poor prognosis.

7 Apr 2007

New role for sugars on proteins

In a ground-breaking study published in the top journal, Cell, Dr. James Dennis, senior investigator at the Samuel Lunenfeld Research Institute at Mount Sinai Hospital, has discovered a new role for sugars on proteins.

7 Apr 2007

RF ablation used to treat early-stage, inoperable cancer

Lung cancer patients who are not candidates for surgery now have another safe and effective treatment option: radiofrequency (RF) ablation, according to a new study published in the April issue of the journal Radiology.

31 Mar 2007

New dimension to understanding of p53 protein

The p53 protein routinely shuts down damaged cells and is one of our main lines of defence against cancer. Scientists at Karolinska Institutet in Sweden now present new findings on how p53 carries out this all-important function.

21 Mar 2007

Inflammation plays key role in the metastasis of prostate cancer

Many would assume that "mounting an immune response" or "having your body fight the cancer" is a good thing.

19 Mar 2007

Obesity at the time of prostate-cancer diagnosis dramatically increases the risk of dying from the disease

Obese men who are diagnosed with prostate cancer have more than two-and-a-half times the risk of dying from the disease as compared to men of normal weight at the time of diagnosis, according to a study by researchers at Fred Hutchinson Cancer Research Center.

15 Mar 2007

Life expectancy doubled for advanced prostate cancer patients

After being diagnosed with aggressive prostate cancer, many men are told that their disease is untreatable and that less aggressive treatment is best.

11 Mar 2007

Improvement of cancer-targeting therapy, using nanocarriers for intractable solid tumors by inhibition of TGF-beta signaling

Administering a small amount of a potent but potentially toxic anticancer agent along with nanoparticles loaded with a second anticancer agent produced a dramatic inhibition of tumor growth in normally intractable cancers. These findings suggest a new approach to treating malignancies such as pancreatic cancer and diffuse gastric cancer.

5 Mar 2007

Sunitinib halts progress of metastatic kidney cancer

Research has shown the efficacy of a pharmaceutical drug known as sunitinib which halts progress of metastatic kidney cancer.

1 Mar 2007

Quantum dots detect metastatic lesions

By injecting quantum dots into tumors, investigators at Carnegie Mellon University have been able to image sentinel lymph nodes in animals using near-infrared light. These results could lead to a simple, non-invasive method for detecting metastasis.

26 Feb 2007

Research defines the cancer role for protein Gab-2

A protein known for its ability to "bridge" interactions between other cellular proteins may spur metastasis in breast cancer, the disease's deadliest stage, a study from Burnham Institute for Medical Research has found.

22 Feb 2007

Why are African American women more likely than White women to die from breast cancer?

Why are African American women 1.5 to 2.2 times more likely than White women to die from breast cancer, despite their lower incidence of the disease? Is it solely because they have less access to medical care? Maybe not, according to a new analysis that will appear in an upcoming issue of the International Journal of Surgery.

22 Feb 2007

Cancer cells 100 times more likely to genetically mutate

When cells become cancerous, they also become 100 times more likely to genetically mutate than regular cells, researchers have found. The findings may explain why cells in a tumor have so many genetic mutations, but could also be bad news for cancer treatments that target a particular gene controlling cancer malignancy.

20 Feb 2007

Noscapine effective against prostate cancer

A presentation made at the 17th International Prostate Cancer Update Conference in Vail, Colorado, has shown noscapine to be effective against prostate cancer.

18 Feb 2007

Watercress shows anti-cancer potential

Eating watercress daily can significantly reduce DNA damage to blood cells, which is considered to be an important trigger in the development of cancer, University of Ulster scientists revealed.

18 Feb 2007

FDA clears MammaPrint test for marketing

The Food and Drug Administration (FDA) has cleared for marketing a test that determines the likelihood of breast cancer returning within five to 10 years after a woman's initial cancer. It is the first cleared molecular test that profiles genetic activity.

6 Feb 2007

Researchers identify human pancreatic cancer stem cells

Researchers at the University of Michigan Medical Center have, for the first time, identified human pancreatic cancer stem cells. Their work indicates that these cells are likely responsible for the aggressive tumor growth, progression, and metastasis that define this deadly cancer.

1 Feb 2007