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New tool reveals mutations that cause HIV-drug resistance

Protease inhibitor drugs are one of the major weapons in the fight against HIV, the virus that causes AIDS, but their effectiveness is limited as the virus mutates and develops resistance to the drugs over time.

11 Jul 2011

AIDS Healthcare Foundation rolls out new national ad campaign

As part of its ongoing advocacy efforts to spur President Obama and his administration to do more on AIDS, AIDS Healthcare Foundation is rolling out a new national ad campaign headlined 'What has the President done about AIDS?' The first leg of the campaign, a series of pointed online text and banner ads on Politico.com's Playbook and Pulse websites started running Monday July 4th on Mike Allen's Politico Playbook and will run through Friday July 15th on Politico's Pulse.

11 Jul 2011

Researchers discover how genetic mutations cause rare human diseases

Researchers at the University of California, San Francisco and in Michigan, North Carolina and Spain have discovered how genetic mutations cause a number of rare human diseases, which include Meckel syndrome, Joubert syndrome and several other disorders.

11 Jul 2011

Scientists convert brain cells into cardiomyocytes

For the past decade, researchers have tried to reprogram the identity of all kinds of cell types. Heart cells are one of the most sought-after cells in regenerative medicine because researchers anticipate that they may help to repair injured hearts by replacing lost tissue.

11 Jul 2011

New genetic clues about ankylosing spondylitis

A study involving over 5,000 people living with the joint disorder ankylosing spondylitis has identified a series of genetic variants associated with increased susceptibility to the condition as well as providing new clues to how the condition may be treated in the future.

11 Jul 2011

Research targets malignant glioma stem cells

Cleveland Clinic researchers have identified a cellular pathway that cancer stem cells use to promote tumor growth in malignant glioma, an aggressive brain tumor.

11 Jul 2011

As Boehner rejects major debt deal, Dems raise Medicare questions

News outlets covered the fallout of House Speaker John Boehner's Saturday announcement. On Sunday talk shows, Democrats insisted the President is "still committed" to solving the deficit problem.

11 Jul 2011

Body builders using greyhound injections to increase muscle mass

According to reports many body builders are injecting drugs meant for greyhounds in the mistaken belief it will help them build bigger muscles faster. L-carnitine is found in supplements sold for human consumption but these users are buying an injectable form from pet shops which experts say can increase the risk of heart attacks. L-carnitine is a quaternary ammonium compound biosynthesized from the amino acids lysine and methionine.

10 Jul 2011

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

Quality Of Care And Patient Outcomes In Critical Access Rural Hospitals -- This study looks at the quality of care provided by patterns of care at "critical access hospitals," a federal designation for hospitals that serve rural populations and thus have been granted special incentives under Medicare.

8 Jul 2011

U.S. leading fight against NTDs

Bernard Pecoul, executive director of the Drugs for Neglected Diseases initiative, and Peter Hotez, president of the Sabin Vaccine Institute and editor-in-chief of PLoS Neglected Tropical Diseases, write in this PLoS "Speaking of Medicine" blog post that the first-ever neglected tropical diseases (NTDs) meeting of the International Society for Infectious Diseases, which is taking place this weekend in Boston, "offers an opportunity for U.S. policy-makers...

8 Jul 2011

Mass administration of common anti-parasitic is possible new tool in fight against malaria

Ivermectin - an inexpensive, common medication already being used in Africa to treat roundworms that cause river blindness and parasites that cause elephantitis - could also be used to kill mosquitoes carrying malaria parasites, potentially "provid[ing] another useful weapon in the armory against a disease that kills around 800,000 a year, most of them small children and pregnant women," the Guardian's "Global Health Blog" reports (Boseley, 7/6).

8 Jul 2011

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Onconova Therapeutics, Inc., and SymBio Pharmaceuticals Limited announced today that they will collaborate to develop and commercialize rigosertib in Japan and Korea. Onconova is conducting late-stage clinical trials with rigosertib (ON 01910.Na) in the U.S., Europe and India for the treatment of Myelodysplastic Syndromes (MDS) and solid tumors.

8 Jul 2011

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

A discovery by University of Alabama at Birmingham researchers about a how a common cell pathway that helps regulate cell survival and production is turned on could lead to new treatments for autoimmune diseases and cancer.

8 Jul 2011

India will continue to produce generic HIV drugs, Commerce and Industry Minister says

"India will not compromise on drug licensing norms and [will] continue to produce generic drugs for free treatment to HIV-positive patients, Commerce and Industry Minister Anand Sharma said" on Wednesday, the IANS/Times of India reports.

8 Jul 2011

Cloud computing technology shortens development time for new antibiotics

IBM today announced researchers from science and technology university ETH Zurich and CloudBroker, a high-performance cloud computing company, have partnered with IBM to use cloud computing technology to conduct cutting-edge research focused on developing new antibiotics to fight disease.

8 Jul 2011

EU countries should pool funding to create 'prize' for bringing new antibiotics to market, report says

"European policy makers were urged Wednesday to find viable financial incentives to get drug companies to discover new antibiotics, because the lack of fresh supplies poses acute dangers to health care and efforts against infectious diseases," according to a report by the Office of Health Economics and funded by GlaxoSmithKline, Dow Jones/Wall Street Journal reports.

8 Jul 2011

Scientists discover mechanism that enables developing cancer cells to sustain abnormal growth

Scripps Research Institute scientists have discovered a basic mechanism that can enable developing cancer cells to sustain abnormal growth. The finding is expected to lead to the targeting of this mechanism with drugs and diagnostic techniques.

8 Jul 2011

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

Identifying a suitable donor for leukemia and lymphoma patients who need bone marrow transplants may be far easier now that results of two clinical trials show transplant results with half-matched bone marrow or umbilical cord blood are comparable to fully matched tissue, thanks in large part to the availability of effective antirejection drugs and special post-transplant chemotherapy.

8 Jul 2011

New strategy may combat age-associated infertility and birth defects

A strategy that has been shown to reduce age-related health problems in several animal studies may also combat a major cause of age-associated infertility and birth defects.

8 Jul 2011

New technique shields patients from toxic parts of antibiotic drug

A new technique which targets antibiotic-resistant bacteria and shields patients from the toxic parts of an antibiotic drug has been developed by Cardiff University scientists.

8 Jul 2011

Drugs News and Research

New tool reveals mutations that cause HIV-drug resistance

AIDS Healthcare Foundation rolls out new national ad campaign

Researchers discover how genetic mutations cause rare human diseases

Scientists convert brain cells into cardiomyocytes

New genetic clues about ankylosing spondylitis

Research targets malignant glioma stem cells

As Boehner rejects major debt deal, Dems raise Medicare questions

Body builders using greyhound injections to increase muscle mass

Research roundup: Rural hospitals have poorer quality; Cost-effective migraine relief; Doctors still take Medicare

U.S. leading fight against NTDs

Mass administration of common anti-parasitic is possible new tool in fight against malaria

Onconova, SymBio enter commercialization collaboration for rigosertib in Japan and Korea

Common cell pathway could lead to new treatments for autoimmune diseases and cancer

India will continue to produce generic HIV drugs, Commerce and Industry Minister says

Cloud computing technology shortens development time for new antibiotics

EU countries should pool funding to create 'prize' for bringing new antibiotics to market, report says

Scientists discover mechanism that enables developing cancer cells to sustain abnormal growth

Transplants with half-matched bone marrow or cord blood are comparable to fully matched tissue

New strategy may combat age-associated infertility and birth defects

New technique shields patients from toxic parts of antibiotic drug

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