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Study reveals crucial role of histone deacetylases in type 2 diabetes

A uniquely collaborative study by researchers at the Salk Institute for Biological Studies uncovered a novel mechanism that turns up glucose production in the liver when blood sugar levels drop, pointing towards a new class of drugs for the treatment of metabolic disease.

16 May 2011

Scientists discover new class of compounds that selectively block 'serine hydrolases'

Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.

16 May 2011

Techulon receives U.S. patent protection for Glycofect Discovery and Therapeutic Delivery Platform

Techulon, Inc. announced today that its Glycofect Discovery and Therapeutic Delivery Platform has been awarded United States patent protection. The patented invention provides a new class of non-viral transfection vectors based on synthetic carbohydrate containing polyamides that can be used for both in vivo and in vitro applications.

16 May 2011

Teva signs definitive agreement to acquire Taiyo

Teva Pharmaceutical Industries Ltd. announced today that it has signed a definitive agreement to acquire 57% of the shares in privately-held Taiyo Pharmaceutical Industry Co. Ltd. for $460 million in cash paid to private shareholders.

16 May 2011

Obese men may face high risk of prostate cancer progression

Even when treated with hormone therapy to suppress tumor growth, obese men face an elevated risk of their prostate cancer worsening, researchers at Duke University Medical Center have found.

16 May 2011

Merck receives FDA approval for Victrelis to treat chronic hepatitis C

The U.S. Food and Drug Administration today approved Victrelis (boceprevir) to treat certain adults with chronic hepatitis C. Victrelis is used for patients who still have some liver function, and who either have not been previously treated with drug therapy for their hepatitis C or who have failed such treatment.

16 May 2011

AIDS spread prevention by vaccine and anti HIV drugs

A latest vaccine against HIV/AIDS has shown to be effective in monkeys and has protected macaques the most widespread primate genus, against the monkey equivalent of HIV, Simian immunodeficiency virus (SIV). This could provide a fresh approach to an HIV vaccine, a study suggests. US researchers say the vaccine offered protection to 13 of 24 Rhesus macaques treated in the experiment. In 12 of the monkeys, the vaccine was still effective 12 months later.

15 May 2011

Genetic link for depression found: Study

Researchers have for the first time confirmed a specific genetic link to depression, according to new evidence published in the American Journal of Psychiatry on Monday. This finding was made independently by research teams in the UK and US, is expected to lead to a better biological understanding of the condition and eventually to more effective antidepressants.

15 May 2011

Evidence of damaged baby brains & inadequate anesthetic induced sleep: Conference updates

According to new studies commonly used anesthetics may be causing brain damage in people, especially babies who receive them while their brains are still developing.

15 May 2011

Early treatment of HIV makes infection transmission less likely: Study

“It's a game-changer,” Michel Sidibe, executive director of UNAIDS, said. “I am completely amazed.” It was noted that anti-HIV drugs called antiretroviral drugs can suppress HIV in an infected patient and also help to prevent its spread through intercourse, he said. He predicted a rethink of the strategies that have evolved since the first cases of AIDS were recorded in June 1981. “The implications are multiple,” said Mr Sidibe. “However, money will be the major challenge.”

15 May 2011

Scientists 'tinker' with HIV drug chemistry hoping to reduce costs

The Clinton Health Access Initiative, founded by former President Bill Clinton, with funding from the Bill & Melinda Gates Foundation and the U.K. government, has hired former pharmaceutical company scientists "to tinker with the chemistry used to synthesize a key [HIV] drug, tenofovir" in an effort to reduce "the cost of manufacturing," the Wall Street Journal reports.

13 May 2011

Supreme Court of Canada opens hearings on safe drug injection facility

The Supreme Court of Canada on Thursday began hearing the Canadian government's case against Insite, a Vancouver-based legal injection site where people can obtain clean needles and syringes to inject their own drugs under a nurse's supervision, the Canadian Press reports. Proponents of the program say it "prevents overdose deaths, reduces the spread of HIV and hepatitis, and curbs crime and open drug use".

13 May 2011

Medical Facilities first quarter revenue increases to $51.7 million

Medical Facilities Corporation, today reported its financial results for the three-month period ended March 31, 2011.

13 May 2011

PCR testing for B. burgdorferi bacteria in joint fluid may confirm Lyme arthritis diagnosis

New research shows that polymerase chain reaction testing for Borrelia burgdorferi DNA—the spirochetal bacteria transmitted by deer ticks—in joint fluid may confirm the diagnosis of Lyme arthritis, but is not a reliable indicator for active joint infection in patients whose arthritis persists after antibiotic therapy. Findings of this study are published in Arthritis & Rheumatism, a journal of the American College of Rheumatology.

13 May 2011

Researchers uncover unexpected role of estrogen receptors in brain inflammation

Researchers have uncovered an unexpected role for estrogen receptors in the brain in keeping inflammation under control. The findings reported in the May 13 issue of the Cell Press journal Cell may have important implications for the treatment of multiple sclerosis (MS) and many other neurodegenerative diseases.

13 May 2011

Tips for fighting drug-resistant superbugs

Superbug CRKP is just the latest in emerging strains of drug-resistant bacteria. While new drugs to combat these stealthy microbes like MRSA and CRKP remain in development what can we do to prevent catching and spreading these dangerous bugs?.

13 May 2011

UCSD scientists discover steroid hormone that inhibits brain inflammation

Researchers at the University of California, San Diego School of Medicine have discovered a steroid hormone that inhibits inflammation in the brain. The findings, to be published in the May 13 issue of the journal Cell, have implications for understanding the exaggerated inflammatory responses that are characteristic features of numerous neurodegenerative diseases.

13 May 2011

Rethink praises Ontario's decision to provide breast cancer patients with access to Herceptin

Today, Rethink Breast Cancer (Rethink) applauds the Ontario government's decision to provide breast cancer patients with tumours less than or equal to 1 cm access to the revolutionary drug Herceptin under the new Evidence Building Program.

13 May 2011

Gene manipulation can improve survival rates during sepsis infection

Sepsis is a major killer in hospital intensive care units. Researchers at Case Western Reserve University School of Medicine have found that manipulating a genetic factor that can launch or throttle the body's defenses can improve survival rates during bacterial infection.

13 May 2011

TFAH applauds HHS for new strategic approach to prevent viral hepatitis

The Trust for America's Health applauds the U.S. Department of Health and Human Services for unveiling a new strategic approach to dealing with the silent epidemic of viral hepatitis today.

13 May 2011