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Researchers unveil new role of thymic dendritic cells in controlling T lymphocyte egress into the blood

A team of scientists led by Julie Saba, MD, PhD at UCSF Benioff Children's Hospital Oakland, has unveiled a novel role of thymic dendritic cells, which could result in new strategies to treat conditions such as autoimmune diseases, immune deficiencies, prematurity, infections, cancer, and the loss of immunity after bone marrow transplantation.

6 Dec 2016

Novel imaging agent can rapidly and accurately detect metastasis of prostate cancer

New research demonstrates that a novel imaging agent can quickly and accurately detect metastasis of prostate cancer, even in areas where detection has previously been difficult.

2 Dec 2016

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells.

1 Dec 2016

Novel imaging technique shows promise to detect, monitor and guide therapy for prostate cancer

An international group of researchers report success in mice of a method of using positron emission tomography scans to track, in real time, an antibody targeting a hormone receptor pathway specifically involved in prostate cancer.

1 Dec 2016

Study reveals why air pollutants cause some people to be at risk for atopic dermatitis

Tohoku University Graduate School of Medicine and Tohoku Medical Megabank Organization are pleased to announce the published results of a study into why air pollutants cause some people to be more susceptible to atopic dermatitis, a kind of skin inflammation.

29 Nov 2016

Japanese researchers discover new method for predicting congenital CMV infection in fetuses

Congenital cytomegalovirus (CMV) infection can cause serious complications such as hearing difficulties and mental retardation in affected infants.

25 Nov 2016

NTM lung infections

Nontuberculous mycobacteria are part of a group of bacteria called mycobacteria. The non-tuberculous mycobacteria are, as the name suggests, mycobacteria that are not tuberculosis. They're also not leprosy, but they are the other members of the bacteria group termed mycobacteria.

23 Nov 2016

Researchers uncover new clues that may help combat leukemia and other B cell cancers

When B lymphocytes (a type of white blood cell in the immune system geared for fighting diseases) turn cancerous, they become part of the problem, and need to be eliminated.

22 Nov 2016

Study shows new drug combination effective in treating precancerous skin lesions

A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from Washington University School of Medicine in St. Louis and Harvard Medical School, shows that the therapy activates the immune system's T cells, which then attack the abnormal skin cells.

21 Nov 2016

Most rapid diagnostic tests fail to detect P. falciparum malaria parasites in asymptomatic children

The Democratic Republic of the Congo has one of the highest rates of people living with malaria. Rapid diagnostic tests (RDTs) account for more than 70 percent of diagnostic testing for malaria in Africa.

17 Nov 2016

Veterans Affairs researchers discover alleles of certain genes that offer protection from GWI

Veterans Affairs researchers have found that certain forms, or alleles, of a gene known to play a key role in the immune system appear to offer protection from Gulf War illness (GWI). Further, they discovered how such protection is manifested in the brain.

17 Nov 2016

Crowdsourcing new prediction tool for better prognosis of metastatic castration-resistant prostate cancer

Knowing the likely course of cancer can influence treatment decisions. Now a new prediction model published today in Lancet Oncology offers a more accurate prognosis for a patient's metastatic castration-resistant prostate cancer.

16 Nov 2016

New research shows how synthetic DNA vaccine approach protects against Zika virus infection

As the global spread of the Zika virus continues, efforts are underway to halt the disease's transmission.

10 Nov 2016

Vaccine-related rubella virus causes harm in some patients with primary immunodeficiency disorders

Some patients with rare primary immunodeficiency disorders may be at risk for infection by rubella virus, and possibly serious skin inflammation, after receiving the rubella vaccine, usually administered as part of the measles-mumps-rubella (MMR) vaccine.

7 Nov 2016

FDA approves expanded use of systemic therapy for treating chronic moderate-to-severe pediatric psoriasis

Amgen today announced that the U.S. Food and Drug Administration has approved the supplemental Biologics License Application for the expanded use of ENBREL (etanercept), making it the first and only systemic therapy to treat pediatric patients (ages 4-17) with chronic moderate-to-severe plaque psoriasis.

7 Nov 2016

TB bacteria can be divided into generalists and specialists, study finds

Tuberculosis (TB) is a major global public health problem. Treatment often takes many months and till this day there is no effective vaccine. Various TB bacterial strains exist globally, with different geographical spread. Only the so-called Lineage 4 occurs on all continents.

4 Nov 2016

Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Combination therapy utilizing two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side effects linked to an unexpected immune response.

4 Nov 2016

Study questions recommendation against PSA screening

Since the U.S Preventative Services Task Force recommended against prostate-specific antigen (PSA) screening for prostate cancer, there has been a significant decrease in the number of prostate biopsies and prostate cancer surgeries across the nation, report researchers.

3 Nov 2016

Fred Hutchinson opens first-of-its-kind clinic to provide new immunotherapies for cancer patients

Fred Hutchinson Cancer Research Center today announced the official opening of a first-of-its-kind clinic dedicated to providing innovative immunotherapies for cancer patients in clinical trials.

2 Nov 2016

Scientists discover previously unknown mechanism that prevents autoimmune disease

A previously unknown safety mechanism in our immune system keeps the body free from autoimmune diseases.

1 Nov 2016