Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Exosome Diagnostics today announced the initial close of its Series B financing round with the raising of $27 million. Proceeds will be used to advance development of the Company's proprietary platform technology and commercial programs for non-invasive, fluid-based molecular diagnostics in oncology, neurodegenerative diseases and other clinical areas.

11 Mar 2014

Plaque in brain could guide treatment decisions for patients at risk for Alzheimer's

Brain imaging using radioactive dye can detect early evidence of Alzheimer's disease that may predict future cognitive decline among adults with mild or no cognitive impairment, according to a 36-month follow-up study led by Duke Medicine.

11 Mar 2014

Almac establishes regional hubs in Singapore and Japan to conduct clinical trials in Asia

Almac today announced the expansion of its clinical services and technologies capabilities to include on-the-ground leadership as well as technical, project and operational resources in Asia.

11 Mar 2014

Sugars attached to proteins can be used to detect ovarian cancer, say researchers

The hunt is on to find biomarkers that detect cancer, but it's a challenging process. Early successes often are followed by heartbreaking failures. But now, researchers at UC Davis have verified that glycans (sugars attached to proteins) can be used to detect ovarian cancer. The study was published online in the journal Cancer Epidemiology, Biomarkers & Prevention.

11 Mar 2014

Scientists discover new protein that drive metastasis of cancer cells

An international team of researchers led by scientists at The Wistar Institute have discovered and defined LIMD2, a protein that can drive metastasis, the process where tumors spread throughout the body.

11 Mar 2014

Nerve growth factor may be dynamic marker of OAB pathophysiology

Urine levels of nerve growth factor fluctuate in line with changes in bladder pathophysiology, a 5-year study of people with overactive bladder has found.

10 Mar 2014

Trophos' olesoxime shows beneficial effect on maintaining motor function in SMA patients

Trophos today announces that top-line results from a pivotal clinical trial of its lead product candidate olesoxime in spinal muscular atrophy (SMA) show a beneficial effect on the maintenance of motor function in SMA patients. If approved, olesoxime could be the first treatment specifically developed for SMA patients.

10 Mar 2014

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Edison Pharmaceuticals today announced the initiation of a phase 2B/3 study entitled, "A Phase 2B/3 Open-label Study of EPI-743 in Children with Leigh Syndrome" to be conducted in conjunction with Dainippon Sumitomo Pharma Co, Ltd.

10 Mar 2014

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Three longtime allies have joined forces to create the new Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence.

7 Mar 2014

Boston Heart Diagnostics announces commercial launch of FDA-cleared MPO test

Boston Heart Diagnostics Corporation, a pioneer in integrating next-generation diagnostics into personalized nutrition and lifestyle programs for patients with or at risk for heart disease, announced the commercial launch of an FDA-cleared MPO (myeloperoxidase) test, a key biomarker for inflammation. Studies show that MPO levels are useful predictors of near-term (one to six months) risk of heart attack or stroke.

6 Mar 2014

Scientists develop reliable way of detecting prostate and bladder cancers

A new licence announced today between the University of Surrey and Randox, will bring to market a new test that will help with the early detection of prostate and bladder cancers.

From Randox Laboratories Ltd. 6 Mar 2014

Curie-Cancer, DNA Therapeutics renew partnership to identify new class of cancer drugs

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and DNA Therapeutics, a biopharmaceutical company that is developing a new class of cancer drugs, are renewing their partnership.

5 Mar 2014

Bruker launches new, improved customer-driven products at Pittcon 2014

At Pittcon 2014, Bruker today announced new product introductions and enhancements for improved performance and customer experience in research, industrial and applied markets.

4 Mar 2014

New research project explores link between pitch count and throwing arm injuries

The correlation between pitch count and throwing arm injuries has been a hot-button issue in baseball for years and now is the focus of a pioneering study by the Mercyhurst University Department of Sports Medicine, UPMC Hamot and Shriners Hospitals for Children - Erie.

4 Mar 2014

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

A team of researchers from National University of Singapore (NUS) have created the first two-photon, small molecule fluorogenic probe that can serve as a useful tool for the rapid assessment of an individual's potential risk for Parkinson's disease.

3 Mar 2014

Atopix presents positive results of Phase IIb asthma study at AAAAI meeting

Atopix Therapeutics Ltd ("Atopix"), a biopharmaceutical company developing innovative CRTH2 antagonists for allergic disease, announced the results of a Phase IIb asthma study with their lead compound OC459 at the American Academy of Allergy, Asthma and Immunology (AAAAI) Annual Meeting , San Diego, California, USA on March 1st.

3 Mar 2014

Biomarker News and Research

Further Reading

Exosome Diagnostics closes Series B financing round with the raising of $27 million

Plaque in brain could guide treatment decisions for patients at risk for Alzheimer's

Almac establishes regional hubs in Singapore and Japan to conduct clinical trials in Asia

Sugars attached to proteins can be used to detect ovarian cancer, say researchers

Scientists discover new protein that drive metastasis of cancer cells

Nerve growth factor may be dynamic marker of OAB pathophysiology

Trophos' olesoxime shows beneficial effect on maintaining motor function in SMA patients

Edison Pharmaceuticals initiates Phase 2B/3 study of EPI-743 in children with Leigh syndrome

Longtime allies team up to create Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence

Boston Heart Diagnostics announces commercial launch of FDA-cleared MPO test

Scientists develop reliable way of detecting prostate and bladder cancers

Curie-Cancer, DNA Therapeutics renew partnership to identify new class of cancer drugs

Bruker launches new, improved customer-driven products at Pittcon 2014

New research project explores link between pitch count and throwing arm injuries

New molecule fluorogenic probe for rapid assessment of individual's risk for Parkinson's disease

Atopix presents positive results of Phase IIb asthma study at AAAAI meeting

PerkinElmer launches Lamina slide scanner for clearer visualization of protein biomarker in tissue

Phase III studies show tiotropium delivered via Respimat inhaler proves effective in asthma patients

BDNF abnormalities may predict bipolar disorder

FSU researchers study smart technology that can search for autism, communication delays in infants

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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